Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cyntia De Piano"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 65
Use of carbapenem antibiotics to treat infections caused by Enterobacterales expressing increasingly aggressive extended-spectrum β-lactamases (ESBL) has contributed to the emergence of carbapenem resistance. Enmetazobactam is a novel ESBL inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0712ced0caeec80e93d6ebb8bb1e27e3
https://doi.org/10.1128/aac.00926-21
https://doi.org/10.1128/aac.00926-21
Publikováno v:
Antimicrob Agents Chemother
The use of carbapenem antibiotics to treat infections caused by Enterobacterales expressing increasingly aggressive extended-spectrum β-lactamases (ESBLs) has contributed to the emergence of carbapenem resistance. Enmetazobactam is a novel ESBL inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9073effa67d4e7982a34d512e997e46c
https://pubmed.ncbi.nlm.nih.gov/34097479
https://pubmed.ncbi.nlm.nih.gov/34097479
Autor:
Nicolas Sprynski, Ian Morrissey, Clarisse Lozano, David T. Davies, Carole A. Sable, Marc Lemonnier, Thomas Valmont, Cyntia De Piano, Adeline Ledoux, Simon Leiris, Agustina Llanos, Martin Everett, Magdalena Zalacain
Publikováno v:
Antimicrobial Agents and Chemotherapy
The global dissemination of metallo-β-lactamase (MBL)-producing carbapenem-resistant Enterobacterales (CRE) is a serious public health concern. Specifically, NDM (New Delhi MBL) has been a major cause of carbapenem therapy failures in recent years,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92e14e96756e579cb8a4fd2e128fd2f
http://europepmc.org/articles/PMC8315971
http://europepmc.org/articles/PMC8315971
Autor:
David T, Davies, Simon, Leiris, Magdalena, Zalacain, Nicolas, Sprynski, Jérôme, Castandet, Justine, Bousquet, Clarisse, Lozano, Agustina, Llanos, Laethitia, Alibaud, Srinivas, Vasa, Ramesh, Pattipati, Ravindar, Valige, Bhaskar, Kummari, Srinivasu, Pothukanuri, Cyntia, De Piano, Ian, Morrissey, Kirsty, Holden, Peter, Warn, Francesca, Marcoccia, Manuela, Benvenuti, Cecilia, Pozzi, Giusy, Tassone, Stefano, Mangani, Jean-Denis, Docquier, David, Pallin, Richard, Elliot, Marc, Lemonnier, Martin, Everett
Publikováno v:
Journal of medicinal chemistry. 63(24)
The diazabicyclooctanes (DBOs) are a class of serine β-lactamase (SBL) inhibitors that use a strained urea moiety as the warhead to react with the active serine residue in the active site of SBLs. The first in-class drug, avibactam, as well as sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e07e1cd1c01e765679dc31f45fa020e
https://pubmed.ncbi.nlm.nih.gov/33306385
https://pubmed.ncbi.nlm.nih.gov/33306385
Autor:
Nicolas Sprynski, Simon Leiris, Kirsty Holden, Srinivasu Pothukanuri, Martin Everett, Agustina Llanos, Manuela Benvenuti, Srinivas Vasa, David T. Davies, Francesca Marcoccia, Richard Elliot, Magdalena Zalacain, Clarisse Lozano, Peter Warn, David Pallin, Cecilia Pozzi, Justine Bousquet, Ian Morrissey, Marc Lemonnier, Ravindar Valige, Bhaskar Kummari, G. Tassone, Jean Denis Docquier, Stefano Mangani, Jérôme Castandet, Ramesh Pattipati, Laethitia Alibaud, Cyntia De Piano
The diazabicyclooctanes (DBOs) are a class of serine β-lactamase (SBL) inhibitors that use a strained urea moiety as the warhead to react with the active serine residue in the active site of SBLs. The first in-class drug, avibactam, as well as sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d974eab718ab77cc1b0732365a12c9e0
http://hdl.handle.net/11365/1125122
http://hdl.handle.net/11365/1125122
Publikováno v:
IUBMB Life. 70:836-844
Bacterial persistence, the ability of bacteria to survive high concentrations of antibiotics for extended periods of time, is an important contributing factor to therapy failure and development of chronic and recurrent infections. Several recent stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc540004533b762369e965c13deb5c59
https://doi.org/10.1002/iub.1888
https://doi.org/10.1002/iub.1888
Autor:
Ian Morrissey, Cedric Charrier, Stephen Hawser, Anne Santerre Henriksen, Morton Alexander, Cyntia De Piano
Publikováno v:
Open Forum Infectious Diseases
Background Mecillinam is a unique amidinopenicillin antibiotic, being the first and the only compound in its class. In contrast to other beta-lactams, it has a unique mechanism of action whereby it exerts its antibacterial activity through binding to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fd3c9d572004c1af44db8692c613c1
https://doi.org/10.1093/ofid/ofaa439.1797
https://doi.org/10.1093/ofid/ofaa439.1797
Publikováno v:
Access Microbiology
In this pilot study, the in vitro antimicrobial activity of iclaprim, a diaminopyrimidine, tested in combination with other antimicrobials against recent and common Gram-positive and Gram-negative respiratory pathogens, was examined by the checkerboa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b9d067be13bd4a1775eec539a37aa3
https://doi.org/10.1099/acmi.0.000027
https://doi.org/10.1099/acmi.0.000027
Publikováno v:
IUBMB life. 70(9)
Bacterial persistence, the ability of bacteria to survive high concentrations of antibiotics for extended periods of time, is an important contributing factor to therapy failure and development of chronic and recurrent infections. Several recent stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92282ec75adb00a4ff1360c8451f5cf2
https://pubmed.ncbi.nlm.nih.gov/30092117
https://pubmed.ncbi.nlm.nih.gov/30092117
Autor:
John D. McKinney, Eleonora Simeoni, Alexandre de Titta, Melody A. Swartz, Neeraj Dhar, Jeffrey A. Hubbell, André J. van der Vlies, Miriella Pasquier, Marie Ballester, Chiara Nembrini, Cyntia De Piano
Publikováno v:
Vaccine
Vaccines that drive robust T-cell immunity against Mycobacterium tuberculosis (Mtb) are needed both for prophylactic and therapeutic purposes. We have recently developed a synthetic vaccine delivery platform with Pluronic-stabilized polypropylene sul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94df4720cdffeb948420cd82497d3a14
https://pubmed.ncbi.nlm.nih.gov/21787826
https://pubmed.ncbi.nlm.nih.gov/21787826