Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Cynthia Tremblay"'
Autor:
Cristina R. Bosoi, Milène Vandal, Marine Tournissac, Manon Leclerc, Hortense Fanet, Patricia L. Mitchell, Mélanie Verreault, Jocelyn Trottier, Jessica Virgili, Cynthia Tremblay, H. Robert Lippman, Jasmohan S. Bajaj, Olivier Barbier, André Marette, Frédéric Calon
Publikováno v:
Hepatology Communications, Vol 5, Iss 3, Pp 446-460 (2021)
Obesity and diabetes are strongly associated not only with fatty liver but also cognitive dysfunction. Moreover, their presence, particularly in midlife, is recognized as a risk factor for Alzheimer’s disease (AD). AD, the most common cause of deme
Externí odkaz:
https://doaj.org/article/02298c17002c4c8fb6c74668f3e1bf85
Autor:
Loïka Maltais, Martin Montagne, Mikaël Bédard, Cynthia Tremblay, Laura Soucek, Pierre Lavigne
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174413 (2017)
It is classically recognized that the physiological and oncogenic functions of Myc proteins depend on specific DNA binding enabled by the dimerization of its C-terminal basic-region-Helix-Loop-Helix-Leucine Zipper (b-HLH-LZ) domain with that of Max.
Externí odkaz:
https://doaj.org/article/47ee33916a1247eab6532ff7bd65aafa
Autor:
Rubens Alexandre da Silva, Audrey-Ann Blais, Patrice Tremblay, Julie Bouchard, Sharlene Côté, Laury Guarnaccia, Léane Tremblay, Sandrine Laflamme-Thibault, Cynthia Tremblay
Publikováno v:
Physical & Occupational Therapy In Geriatrics. 39:370-386
Aims: The assessment of the risk of falling in geriatric rehabilitation is often using standardized functional tests, which may be more complex but less representative in older adults with a neuroc...
Autor:
Cynthia Tremblay, Patrick Delattre, Émilie Jolibois, Danny Létourneau, Olivier Boisvert, Martin Montagne, Pierre Lavigne
Publikováno v:
SSRN Electronic Journal.
Miz-1 (ZBTB17) is a poly-Zinc Finger BTB/POZ transcription factor with 12 consecutive C2H2 Zinc Fingers (ZFs). Miz-1 binds transcriptional start sites (TSS), through a consensus sequence, to regulate the expression of genes involved in the cell cycle
Autor:
Olivier Boisvert, Danny Létourneau, Patrick Delattre, Cynthia Tremblay, Émilie Jolibois, Martin Montagne, Pierre Lavigne
Publikováno v:
Structure. 30:623-636.e5
Miz-1 (ZBTB17) is a poly-zinc finger BTB/POZ transcription factor with 12 consecutive C2H2 zinc fingers (ZFs) that binds transcriptional start sites (TSSs) to regulate the expression of genes involved in cell development and proliferation. As of now,
Autor:
Mélanie Verreault, Olivier Barbier, Marine Tournissac, Milène Vandal, Cristina R. Bosoi, Manon Leclerc, Patricia L. Mitchell, André Marette, Frédéric Calon, Jessica Virgili, H. Robert Lippman, Jocelyn Trottier, Jasmohan S. Bajaj, Cynthia Tremblay, Hortense Fanet
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 5, Iss 3, Pp 446-460 (2021)
Hepatology Communications, Vol 5, Iss 3, Pp 446-460 (2021)
Long‐term high‐fat diet–induced changes in liver function impact peripheral AD features and should be considered during development of biomarkers or therapeutic targets.
Obesity and diabetes are strongly associated not only with fatty live
Obesity and diabetes are strongly associated not only with fatty live
Autor:
Erika Serrano del Pozo, Christopher Fiore, Miguel Ángel Morcillo Alonso, Loïka Maltais, Sílvia Casacuberta-Serra, Marie-Eve Beaulieu, Danny Létourneau, Laura Soucek, Génesis Martín, Peter B. Rahl, Laia Foradada, Marta Oteo, Sandra Martínez-Martín, Eduardo Romero Sanz, Jonathan Whitfield, Virginia Castillo Cano, Toni Jauset, Matthew G. Guenther, Martin Montagne, Cynthia Tremblay, Meritxell Sánchez-Hervás, Daniel Massó-Vallés, Pierre Lavigne, Mariano F. Zacarias-Fluck
Publikováno v:
Science Translational Medicine
Inhibiting MYC has long been considered unfeasible, although its key role in human cancers makes it a desirable target for therapeutic intervention. One reason for its perceived undruggability was the fear of catastrophic side effects in normal tissu
Autor:
Milène Vandal, Ariane Giguère-Rancourt, Marie-Thérèse Traversy, Cynthia Tremblay, Marine Tournissac, Frédéric Calon
Publikováno v:
Alzheimer's & Dementia. 12
Publikováno v:
Biochemical and biophysical research communications. 473(2)
Miz-1 is a BTB/POZ transcription factor that contains 13C2H2 Zinc Finger domains (ZF). Miz-1 transactivates and represses the transcription of a myriad of genes involved in many aspects of the biology of the cell. The detailed molecular interactions
Autor:
Christopher Fiore, Peter B. Rahl, Marta Oteo Vives, Matthew G. Guenther, Daniel Massó-Vallés, Miguel Ángel Morcillo Alonso, Martin Montagne, Sandra Martínez-Martín, Cynthia Tremblay, Pierre Lavigne, Jonathan Whitfield, Mariano F. Zacarias-Fluck, Marie-Eve Beaulieu, Laura Soucek, Loïka Maltais, Laia Foradada, Erika Serrano del Pozo, Toni Jauset, Silvia Casacuberta, Eduardo Romero Sanz
Publikováno v:
Cancer Research. 77:2167-2167
Deregulation of the MYC oncoprotein promotes tumorigenesis in most, if not all, cancers and is often associated with poor prognosis. However, targeting MYC has long been considered impossible based on the assumption that it would cause catastrophic s