Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cynthia Sprenger"'
Autor:
Christine Henzler, Yingming Li, Rendong Yang, Terri McBride, Yeung Ho, Cynthia Sprenger, Gang Liu, Ilsa Coleman, Bryce Lakely, Rui Li, Shihong Ma, Sean R. Landman, Vipin Kumar, Tae Hyun Hwang, Ganesh V. Raj, Celestia S. Higano, Colm Morrissey, Peter S. Nelson, Stephen R. Plymate, Scott M. Dehm
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Castration-resistant prostate cancer frequently presents with persistent androgen receptor signalling. Here, the authors find that the androgen receptor is subject to genetic rearrangements, resulting in variants with ligand-independent activity.
Externí odkaz:
https://doaj.org/article/881742f5c87d4d33a058d2ab18e6588c
Autor:
Gang Liu, Cynthia Sprenger, Shihua Sun, Kathryn Soriano Epilepsia, Kathleen Haugk, Xiaotun Zhang, Ilsa Coleman, Peter S. Nelson, Stephen Plymate
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 9, Pp 1009-1017 (2013)
Androgen deprivation therapy remains the primary treatment modality for patients with metastatic prostate cancer but is uniformly marked by progression to castration-resistant prostate cancer (CRPC) after a period of regression. Continued activation
Externí odkaz:
https://doaj.org/article/ac1e20ccf5374f3582108d79ea40e1b9
Publikováno v:
Cell Reports Medicine. 3:100493
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e72fc34184bbde0dcb2dcafff1d6c12
https://doi.org/10.1016/j.xcrm.2021.100493
https://doi.org/10.1016/j.xcrm.2021.100493
Autor:
Adam, Sharp, Ilsa, Coleman, Wei, Yuan, Cynthia, Sprenger, David, Dolling, Daniel Nava, Rodrigues, Joshua W, Russo, Ines, Figueiredo, Claudia, Bertan, George, Seed, Ruth, Riisnaes, Takuma, Uo, Antje, Neeb, Jonathan, Welti, Colm, Morrissey, Suzanne, Carreira, Jun, Luo, Peter S, Nelson, Steven P, Balk, Lawrence D, True, Johann S, de Bono, Stephen R, Plymate
Publikováno v:
The Journal of Clinical Investigation
BACKGROUND. Liquid biopsies have demonstrated that the constitutively active androgen receptor splice variant-7 (AR-V7) associates with reduced response and overall survival from endocrine therapies in castration-resistant prostate cancer (CRPC). How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8aca6991993d1a2ca6b78a63c5e6a8c
https://pubmed.ncbi.nlm.nih.gov/30334814
https://pubmed.ncbi.nlm.nih.gov/30334814
Publikováno v:
Journal of Clinical Medicine. Jan2020, Vol. 9 Issue 1, p287-287. 1p.
Publikováno v:
Tenders Info Reports. 3/18/2020, pN.PAG-N.PAG. 1p.
Publikováno v:
Tenders Info Reports. 3/3/2020, pN.PAG-N.PAG. 1p.
Autor:
Damodarasamy, Mamatha, Vernon, Robert, Chan, Christina, Plymate, Stephen, Wight, Thomas, Reed, May
Publikováno v:
In Vitro Cellular & Developmental Biology Animal; Jan2015, Vol. 51 Issue 1, p50-58, 9p
Publikováno v:
Frontiers in Endocrinology; Dec2013, Vol. 4, p1-8, 8p
Autor:
Holly M. Nguyen, Eva Corey, Cynthia C. Sprenger, Kristine van Maltzan, Shihua Sun, Gang Liu, Stephen R. Plymate, Ulrike Weyer-Czernilofsky
Publikováno v:
Cancer Research. 77:1194-1194
Background: Recent data from multiple investigators have shown that an increase in constitutively active androgen receptor (AR) variants such as AR-V7 is associated with more aggressive prostate cancer and a significantly shortened overall survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::205dff2c42c1109c7339aa2c3aa40ed6
https://doi.org/10.1158/1538-7445.am2017-1194
https://doi.org/10.1158/1538-7445.am2017-1194