Výsledky vyhledávání - "Cynthia Sawyez"

Akademický článek

N-acetyl-L-cysteine treatment reduces beta-cell oxidative stress and pancreatic stellate cell activity in a high fat diet-induced diabetic mouse model

Autor: Meg Schuurman, Madison Wallace, Gurleen Sahi, Malina Barillaro, Siyi Zhang, Mushfiqur Rahman, Cynthia Sawyez, Nica Borradaile, Rennian Wang

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

Obesity plays a major role in type II diabetes (T2DM) progression because it applies metabolic and oxidative stress resulting in dysfunctional beta-cells and activation of intra-islet pancreatic stellate cells (PaSCs) which cause islet fibrosis. Admi

Externí odkaz: https://doaj.org/article/8011e86d23284919a5c7b83b87ddba31

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Abstract 70: PPARdelta Agonist GW1516 Attenuates Diet-Induced Dyslipidemia, Insulin Resistance and Aortic Inflammation in Ldlr -/- Mice

Autor: Lazar Bojic, Dawn Telford, Brian Sutherland, Cynthia Sawyez, Jane Edwards, Murray Huff

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 32

Objective: The peroxisome proliferator-activated receptor (PPAR) delta has been implicated in systemic lipid homeostasis and inflammation. However, the role of PPARdelta agonists as anti-atherogenic agents remains unclear. In the present study, we us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8bccac475d509cdc34457aa8f489f16a
https://doi.org/10.1161/atvb.32.suppl_1.a70

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