Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Cynthia S. Smith"'
Autor:
Suramya Waidyanatha, Alfred F Fuciarelli, Steven W. Graves, S. Peter Hong, Cynthia S. Smith, Derrick J. Bates, Jerry D. Johnson
Publikováno v:
Xenobiotica. 43:1010-1017
1. Isoeugenol (IEG) has been tested for toxicity and carcinogenicity due to high potential for human exposure and the structural resemblance to known carcinogenic allylbenzenes. In order to support the interpretation of toxicity and carcinogenecity s
Autor:
Cynthia S. Smith, Derrick J. Bates, Suramya Waidyanatha, Jerry D. Johnson, Alfred F Fuciarelli, Steven W. Graves, S. Peter Hong
Publikováno v:
Xenobiotica. 43:293-302
1. Methyleugenol (MEG) has been used as a flavouring agent in food, as a fragrance in cosmetic products, and as an insect attractant. MEG was carcinogenic in both rats and mice following gavage administration. In this study we investigated plasma tox
Autor:
June K. Dunnick, Cynthia S. Smith, Tim Cristy, Steven W. Graves, Suramya Waidyanatha, Jerry D. Johnson, V.D. Godfrey-Robinson, Seongwon Hong
Publikováno v:
Toxicology Letters. 205:215-226
In the National Toxicology Program’s toxicity studies, rats were more sensitive than mice to Bis(2-chloroethoxy)methane (CEM) – induced cardiac toxicity following dermal application to male and female F344/N rats and B6C3F1 mice. Thiodiglycolic a
Autor:
Molly Vallant, Gary A. Boorman, Ruchir R. Shah, Scott S. Auerbach, Nigel J. Walker, Richard D. Irwin, Cynthia S. Smith, Deepak Mav
Publikováno v:
Toxicology and Applied Pharmacology. 243:300-314
Identification of carcinogenic activity is the primary goal of the 2-year bioassay. The expense of these studies limits the number of chemicals that can be studied and therefore chemicals need to be prioritized based on a variety of parameters. We ha
Autor:
Dama Logan, Brian Hefner, Cynthia S. Smith, J Diane Overstreet, Alice P Clark, Dean E. Gray, Joseph A Algaier, Dale Messer, Andrew Porter, Roger K Harris
Publikováno v:
Journal of AOAC INTERNATIONAL. 90:1203-1209
Advancements in automated high-performance thin-layer chromatography (HPTLC) have made it feasible to assess its use for the quantitative analysis of marker compounds in botanical preparations. We report here the findings of method comparisons for th
Autor:
Alice P Clark, Joseph W Algaier, Roger K Harris, Holly A Weber, Jill R Guthrie, Cynthia S. Smith, David Robaugh, Andrew E Hodges, Brandon M O'Brien
Publikováno v:
Journal of Agricultural and Food Chemistry. 55:148-156
The major constituents in grape seed and pine bark extracts are proanthocyanidins. To evaluate material available to consumers, select lots were analyzed using high-performance liquid chromatography, gas chromatography/mass spectrometry (GC/MS), liqu
Autor:
Marilyn J. Wolfe, Ronald Herbert, Naomi J. Bernheim, William E. Hawkins, Gary A. Boorman, Cynthia S. Smith, Micheal P. Jokinen, Grace E. Kissling
Publikováno v:
Toxicological Sciences. 92:143-156
There has been considerable interest in the use of small fish models for detecting potential environmental carcinogens. In this study, both guppies (Poecilia reticulata) and medaka (Oryzias latipes) were exposed in the aquaria water to three known ro
Autor:
Joseph W Algaier, J Diane Overstreet, Roger K Harris, Andrew Porter, Cynthia S. Smith, Dean E. Gray, Alice P Clark, Sherry Ferguson, Dale Messer
Publikováno v:
Journal of AOAC INTERNATIONAL. 88:1613-1620
We report here a liquid chromatography (LC) method with inline ultraviolet/evaporative light scattering (UV/ELS) detection for the simultaneous quantification of the terpenelactones and flavonol aglycones in a single sample of hydrolyzed Ginkgo bilob
Autor:
Yin-Fong Su, R. Bruce Westerberg, Daniel L. Morgan, Cynthia S. Smith, John C. Turnier, Jeffrey A. Dill
Publikováno v:
American Journal of Industrial Medicine. 46:554-569
Background During installation of cellulose insulation (CI) in new and older houses, significant quantities of airborne material are generated. This study characterized the chemical and physical properties, and potential acute pulmonary toxicity of C
Autor:
J Diane Overstreet, Cynthia S. Smith, Holly A Weber, Brandon M O'Brien, H Michael Molloy, Matthew K Zart, Roger K Harris, Leslie A Moody, Alice P Clark, Andrew E Hodges
Publikováno v:
Journal of Agricultural and Food Chemistry. 51:7352-7358
The characterization of herbal materials is a significant challenge to analytical chemists. Goldenseal (Hydrastis canadensis L.), which has been chosen for toxicity evaluation by NIEHS, is among the top 15 herbal supplements currently on the market a