Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Cynthia Roberts"'
Autor:
Louise Pellegrino Gomes Esporcatte, Marcella Q. Salomão, Bernardo T. Lopes, Paolo Vinciguerra, Riccardo Vinciguerra, Cynthia Roberts, Ahmed Elsheikh, Daniel G. Dawson, Renato Ambrósio
Publikováno v:
Eye and Vision, Vol 7, Iss 1, Pp 1-12 (2020)
Abstract Corneal biomechanics has been a hot topic for research in contemporary ophthalmology due to its prospective applications in diagnosis, management, and treatment of several clinical conditions, including glaucoma, elective keratorefractive su
Externí odkaz:
https://doaj.org/article/f80ba9bf0a77498cb7fe4d9db863dabf
Autor:
Cynthia Roberts, Ruizhuo Ning, Poornima Venkat, Alex Zacharek, Michael Chopp, Tao Yan, Xinchun Ye, Jieli Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 11, Pp 22221-22232 (2013)
Objective: White matter remodeling plays an important role in neurological recovery after stroke. Bone marrow stromal cells (BMSCs) and Niaspan, an agent which increases high density lipoprotein (HDL), each induces neurorestorative effects and promot
Externí odkaz:
https://doaj.org/article/5fd6105acd3441c6938c4b221302d35c
Autor:
Tao Yan, Michael Chopp, Xinchun Ye, Zhongwu Liu, Alex Zacharek, Yisheng Cui, Cynthia Roberts, Ben Buller, Jieli Chen
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 1, Pp 157-164 (2012)
Background and objective: We investigated axonal plasticity in the bilateral motor cortices and the long term therapeutic effect of Niaspan on axonal remodeling after stroke in type-1 diabetic (T1DM) rats. Experimental approaches: T1DM was induced in
Externí odkaz:
https://doaj.org/article/bef88a91f6ec445197eb26335623008b
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 1, Pp 285-292 (2011)
We investigated the changes and the molecular mechanisms of cerebral vascular damage after stroke in type-2 diabetic (T2DM) mice. Adult male db/db T2DM and wild-type (WT) mice were subjected to transient middle cerebral artery occlusion (MCAo) and sa
Externí odkaz:
https://doaj.org/article/fb0a29a9cbe346fa92107c3e033997ae
Autor:
Amjad Shehadah, Jieli Chen, Alex Zacharek, Yisheng Cui, Madalina Ion, Cynthia Roberts, Alissa Kapke, Michael Chopp
Publikováno v:
Neurobiology of Disease, Vol 40, Iss 1, Pp 277-283 (2010)
Introduction: Niaspan, an extended-release formulation of Niacin (vitamin B3), has been widely used to increase high density lipoprotein (HDL) cholesterol and to prevent cardiovascular diseases and stroke. In this study, we tested whether Niaspan adm
Externí odkaz:
https://doaj.org/article/2249fc92c7b641a98b456d04f358527e
Autor:
Xu Cui, Michael Chopp, Alex Zacharek, Cynthia Roberts, Mei Lu, Smita Savant-Bhonsale, Jieli Chen
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 1, Pp 35-41 (2009)
We investigated the additive therapeutic effect of the combination treatment of stroke with sub-therapeutic doses of Simvastatin, a HMG-CoA reductase inhibitor, and bone marrow stromal cells (BMSCs). Rats were administered Simvastatin (0.5 mg/kg), BM
Externí odkaz:
https://doaj.org/article/1da9fda9355b4967b17f5d13122a86c6
Autor:
Jing Zhang, Jieli Chen, Yi Li, Xu Cui, Xuguang Zheng, Cynthia Roberts, Mei Lu, Stanton B. Elias, Michael Chopp
Publikováno v:
Neurobiology of Disease, Vol 32, Iss 2, Pp 273-280 (2008)
We investigated the treatment of experimental autoimmune encephalomyelitis (EAE) in mice with Niaspan, an agent used to elevate high-density lipoprotein (HDL). EAE mice were treated with Niaspan starting on the immunization or clinical onset day. Neu
Externí odkaz:
https://doaj.org/article/d8c6a1e199354461b8baedec29ec72b7
Autor:
Rui Lan Zhang, Michael Chopp, Cynthia Roberts, Xianshuang Liu, Min Wei, Siamak P Nejad-Davarani, Xinli Wang, Zheng Gang Zhang
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113972 (2014)
The unique cellular and vascular architecture of the adult ventricular-subventricular zone (V/SVZ) neurogenic niche plays an important role in regulating neural stem cell function. However, the in vivo identification of neural stem cells and their re
Externí odkaz:
https://doaj.org/article/697a7a08747a4be0b8d699e4ecf5347d
Autor:
Amjad Shehadah, Jieli Chen, Ajai Pal, Shuyang He, Andrew Zeitlin, Xu Cui, Alex Zacharek, Yisheng Cui, Cynthia Roberts, Mei Lu, Robert Hariri, Michael Chopp
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86621 (2014)
BACKGROUND: Human Placenta-Derived Adherent Cells (PDAC®) are a novel mesenchymal-like cell population derived from normal human placental tissue. PDA-001 is a clinical formulation of PDAC® developed for intravenous administration. In this study, w
Externí odkaz:
https://doaj.org/article/f3cff44801a14990840d2ca65773fe18
Autor:
Jieli Chen M.D., Amjad Shehadah, Ajai Pal, Alex Zacharek, Xu Cui, Yisheng Cui, Cynthia Roberts, Mei Lu, Andrew Zeitlin, Robert Hariri, Michael Chopp
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Human placenta-derived adherent (PDA001) cells are mesenchymal-like stem cells isolated from postpartum human placenta. In this study, we tested whether intravenously infused PDA001 improves neurological functional recovery after stroke in rats. In a
Externí odkaz:
https://doaj.org/article/acbe7e72ec5940bd89fd312b39161fdb