Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cynthia R. C. Osborne"'
Autor:
Devchand Paul, Richard McGee, Svetislava J. Vukelja, Scot Sedlacek, Anita Duncan, Michael Kasper, Wally G. Meyer, Andrew B. Schneider, Cynthia R. C. Osborne, Frankie A. Holmes, Joyce A. O'Shaughnessy, Sharon Wilks
Publikováno v:
Breast Cancer Research and Treatment. 116:521-527
Tamoxifen significantly reduces the risk of developing breast cancer in women at increased-risk. The usefulness of tamoxifen has been limited by its side effect profile, especially its propensity to worsen vasomotor symptoms. Hormone therapy (HT) has
Autor:
Yong Lin, Ayman B. Ibrahim, Devchand Paul, Jay Andersen, Denise A. Yardley, Brooke R. Daniel, Foluso O. Ademuyiwa, Paul Richards, Anne Favret, James Reeves, Troy Guthrie, Sanjay P. Oommen, Lea Krekow, Hatem Soliman, Cynthia R. C. Osborne, Adam Brufsky, Janak K. Choksi, E. Claire Dees, Michael A. Danso, Jane Bromund
Publikováno v:
Clinical Breast Cancer. 16(6):471-479.e1
Background Use of antiangiogenic agents in treatment of metastatic breast cancer (MBC) remains controversial. We evaluated the efficacy and safety of ramucirumab and eribulin versus eribulin alone as third- to fifth-line therapy in women with advance
Autor:
Julie R. Nangia, Tao Wang, Mari Rude, Cynthia R. C. Osborne, Steven W. Papish, Jame Abraham, Frankie Ann Holmes, Michael A. Savin, Richard Paxman, Susan G. Hilsenbeck, C. Kent Osborne, Mothaffar F. Rimawi
Publikováno v:
Journal of Clinical Oncology. 34:TPS10144-TPS10144
Autor:
Lea Krekow, Maren K. Levin, Kristi McIntyre, Jeffrey S. Ross, Roman Yelensky, Cynthia R. C. Osborne, Gary A. Palmer, Ying Cao, Joyce O'Shaughnessy, Sohail Balasubramanian, Norma Alonzo Palma, Frankie A. Holmes, Kai Wang
Publikováno v:
Journal of Clinical Oncology. 32:625-625
625 Background: Understanding the molecular alterations in residual, treatment-refractory HER2-positive breast cancer (BC) following preoperative trastuzumab (H), lapatinib (L) or both (HL) in combination with chemotherapy may help identify patients
Autor:
Virginia Espina, Janine M. Mahoney, Yasir Nagarwala, Thomas Anderson, Lance A. Liotta, Allison Florance, Kristi McIntyre, Joyce A. O'Shaughnessy, Frankie A. Holmes, Michael A. Danso, Cynthia R. C. Osborne, Rosa I. Gallagher
Publikováno v:
Journal of Clinical Oncology. 29:506-506
506 Background: Extinction of HER2 signaling in HER2 driven BC may be curative. Alternative activation pathways (HER1, HER3) & mutated downstream signal transducers allow resistance to therapy. Study aim: molecularly characterize HER2+ BC before & af