Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Cynthia R Clark"'
1
Akademický článek
Genetic ablation of serotonin receptor 2B improves aortic valve hemodynamics of Notch1 heterozygous mice in a high-cholesterol diet model.
Autor: J Ethan Joll, Cynthia R Clark, Christine S Peters, Michael A Raddatz, Matthew R Bersi, W David Merryman
Publikováno v: PLoS ONE, Vol 15, Iss 11, p e0238407 (2020)
Calcific aortic valve disease (CAVD) is a deadly disease that is rising in prevalence due to population aging. While the disease is complex and poorly understood, one well-documented driver of valvulopathy is serotonin agonism. Both serotonin overexp
Externí odkaz: https://doaj.org/article/c52a61d3d77848bf9fe6feea4c0dc816
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2
Akademický článek
Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 In Vitro.
Autor: Daniel M DeLaughter, Cynthia R Clark, Danos C Christodoulou, Christine E Seidman, H Scott Baldwin, J G Seidman, Joey V Barnett
Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0159710 (2016)
The epicardium plays an important role in coronary vessel formation and Tgfbr3-/- mice exhibit failed coronary vessel development associated with decreased epicardial cell invasion. Immortalized Tgfbr3-/- epicardial cells display the same defects. Tg
Externí odkaz: https://doaj.org/article/76025aade1e0440483e20299bab1fc46
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3
Genetic ablation of serotonin receptor 2B improves aortic valve hemodynamics of Notch1 heterozygous mice in a high-cholesterol diet model
Autor: Christine S. Peters, Matthew R. Bersi, Cynthia R. Clark, J. Ethan Joll, W. David Merryman, Michael A. Raddatz
Publikováno v: PLoS ONE
PLoS ONE, Vol 15, Iss 11, p e0238407 (2020)
Calcific aortic valve disease (CAVD) is a deadly disease that is rising in prevalence due to population aging. While the disease is complex and poorly understood, one well-documented driver of valvulopathy is serotonin agonism. Both serotonin overexp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d119a08cd2fed79be992a9aec93506b
http://europepmc.org/articles/PMC7688160
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4
Genetic ablation of serotonin receptor 2B improves aortic valve hemodynamics in a high-cholesterol diet mouse model
Autor: Christine S. Peters, W. David Merryman, Matthew R. Bersi, J. Ethan Joll, Michael A. Raddatz, Cynthia R. Clark
Calcific aortic valve disease (CAVD) is a deadly disease that is rising in prevalence due to population aging. While the disease is complex and poorly understood, one well-documented driver of valvulopathy is serotonin agonism. Both serotonin overexp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0752e18e8557fa8f72d398e4bf8fbfc
https://doi.org/10.1101/2020.08.18.255414
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5
Cadherin-11 blockade reduces inflammation-driven fibrotic remodeling and improves outcomes after myocardial infarction
Autor: Thomas Force, Susan M. Majka, Matthew R. Bersi, W. David Merryman, Lehanna H. Sanders, Qinkun Zhang, Antonis K. Hatzopoulos, Cynthia R. Clark, Alison K. Schroer, Hind Lal
BackgroundOver one million Americans experience myocardial infarction (MI) every year, and the resulting scar and subsequent cardiac fibrosis contribute to heart failure and death. A specialized cell-cell adhesion protein, cadherin-11 (CDH11), contri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c93ebdf75f6bdc4aedb9dd67bb3b25
https://europepmc.org/articles/PMC6795284/
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7
Targeting Cadherin-11 Prevents Notch1-Mediated Calcific Aortic Valve Disease
Autor: W. David Merryman, J. Caleb Snider, Cynthia R. Clark, Meghan A. Bowler
Publikováno v: Circulation. 135:2448-2450
Calcific aortic valve disease (CAVD) accounts for ≈15 000 patient deaths per year in the United States, and intervention occurs only when severe stenosis requires surgical replacement of the valve. Recently, it was discovered that long noncoding RN
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58c1f0041788dea69602fa0316cf72a
https://doi.org/10.1161/circulationaha.117.027771
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8
Common pathways regulate Type III TGFβ receptor–dependent cell invasion in epicardial and endocardial cells
Autor: Harold E. Olivey, W. David Merryman, Todd A. Townsend, David Z. Trykall, Charles C. Hong, Cynthia R. Clark, Joey V. Barnett, Julian A. Arrieta, Jamille Y. Robinson, Nora S. Sanchez
Epithelial-Mesenchymal Transformation (EMT) and the subsequent invasion of epicardial and endocardial cells during cardiac development is critical to the development of the coronary vessels and heart valves. The transformed cells give rise to cardiac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13387803e5291fe764775c67f4882779
https://europepmc.org/articles/PMC4827451/
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9
Feasibility of Using the Med-eMonitor System in the Treatment of Schizophrenia: A Pilot Study
Autor: Paul E. Ruskin, Bruce A. Kehr, Ramesh K. Thapar, Janie Deveau, Cynthia R. Clark, Manish Prasad, Joanne Fenton, Judy Van Der Wende
Publikováno v: Drug Information Journal. 37:283-291
Objective: To test the feasibility of using a computerized device called the Med-eMonitor for daily monitoring of medication compliance and symptoms; (o enhance medication and research protocol compliance: and to educate schizophrenic patients and th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33c3793cdd2a28282599553c0cfc9973
https://doi.org/10.1177/009286150303700304
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10
Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 In Vitro
Autor: H. Scott Baldwin, Danos C. Christodoulou, Christine E. Seidman, Jon G. Seidman, Daniel M. DeLaughter, Cynthia R. Clark, Joey V. Barnett
Publikováno v: PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0159710 (2016)
The epicardium plays an important role in coronary vessel formation and Tgfbr3-/- mice exhibit failed coronary vessel development associated with decreased epicardial cell invasion. Immortalized Tgfbr3-/- epicardial cells display the same defects. Tg
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92fd63af7094cbbe59d679074ef242d
https://doi.org/10.1371/journal.pone.0159710
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