Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Cynthia Park"'
Autor:
Kevin Gaida, Xuxia Zhang, Robin Elliott, Benxian Liu, Andrea Itano, Cynthia Park, Justin K. Murray, Colin V. Gegg, Jennifer Aral, Les P. Miranda, Joseph G. McGivern, Hongyan Li, Anne Colombero, E. Allen Sickmier, Kevin Salyers, Michael Stenkilsson, Jonathan Werner, Steven Yu, Mark J. Rose, John K. Sullivan, Yi-Xin Qian, Peter Miu, Kristin L. Andrews
Publikováno v:
Journal of Medicinal Chemistry. 58:6784-6802
To realize the medicinal potential of peptide toxins, naturally occurring disulfide-rich peptides, as ion channel antagonists, more efficient pharmaceutical optimization technologies must be developed. Here, we show that the therapeutic properties of
Publikováno v:
Journal of chromatography. A. 1344
As the pace of drug discovery accelerates there is an increased focus on screening larger numbers of protein therapeutic candidates to identify those that are functionally superior and to assess manufacturability earlier in the process. Although ther
Autor:
Holland Levinson, Cynthia Park, Carol M. Worthman, Joy F. Stallings, Karen Mroz, Mary Ann Handel, Patricia A. Hunt, Renée LeMaire
Publikováno v:
Molecular Reproduction and Development. 49:101-111
Male mammals with two X chromosomes are sterile due to the demise of virtually all germ cells; however, the underlying reasons for the germ cell loss remain unclear. The use of a breeding scheme for the production of XXY male mice has allowed us to e
Publikováno v:
Molecular Reproduction and Development. 46:489-498
Topoisomerases are nuclear enzymes that remove torsional stress in DNA. Their function is important for replication, transcription, chromosome condensation, and chromosome segregation during mitosis and meiosis. The goal of this work is to analyze bo
Publikováno v:
Molecular reproduction and development. 49(1)
During the pachytene stage of meiotic prophase in male mammals, the X and Y chromosomes become transcriptionally inactive and establish a chromatin domain, the sex body, that is visually distinct from the transcriptionally active autosomes. We used o
Publikováno v:
Annals of the New York Academy of Sciences. 637
Autor:
Leszek Wojnowski, Mary Ann Handel, Andreas Zimmer, Willard F. Hollander, Ricardo Berna, Cynthia Park
Publikováno v:
Mammalian Genome. 9:905-906
Induced Premature G2/M-Phase Transition in Pachytene Spermatocytes Includes Events Unique to Meiosis
Publikováno v:
Developmental Biology. (2):557-567
Little is known about the control of events ending the lengthy prophase of meiosis I and leading to the G2/M-phase transition in mammalian spermatocytes, primarily because the relevant late pachytene, diplotene, and MI cells are present in low number
Autor:
Robert N. St. Clair, Cynthia Park
Publikováno v:
Linguistics. 12
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