Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Cynthia P. Breeden"'
Autor:
Cynthia P. Breeden, Jose L. Estrada, Andrew B. Adams, Alfred J. Tector, Luz M. Reyes, Christopher Burlak, Brendan P. Lovasik, Matthew Tector, David A. Faber, Rodrigo M. Vianna
Publikováno v:
Ann Surg
OBJECTIVE Pig-to-primate renal xenotransplantation is plagued by early antibody-mediated graft loss which precludes clinical application of renal xenotransplantation. We evaluated whether temporary complement inhibition with anti-C5 antibody Tesidolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168ea7cb013a0eaa3d4dd766a4e934de
https://doi.org/10.1097/sla.0000000000004996
https://doi.org/10.1097/sla.0000000000004996
Autor:
Elizabeth Strobert, Laura B. Higginbotham, Alfred Joseph Tector, Joseph M. Ladowski, Andrew B. Adams, Eric M. Walters, David V. Mathews, Alton B. Farris, Joe B. Jenkins, Gregory Martens, Cynthia P. Breeden, Christian P. Larsen, Allison Stephenson, Matthew Tector, Steven C. Kim
Publikováno v:
Am J Transplant
The shortage of available organs remains the greatest barrier to expanding access to transplantation. Despite advances in genetic editing and immunosuppression, survival in experimental models of kidney xenotransplantation has generally been limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b87a5734a4f63a76438da9209baf92
https://doi.org/10.1111/ajt.15329
https://doi.org/10.1111/ajt.15329
Autor:
Christian P. Larsen, Andrew B. Adams, Elizabeth A. Stobert, Laura B. Higginbotham, David V. Mathews, J. Yun Tso, Ying Dong, Joseph Jenkins, Cynthia P. Breeden, Steven C. Kim
Publikováno v:
Journal of Clinical Investigation. 128:4557-4572
Interrupting T cell costimulatory signals as a strategy to control undesired immune responses, such as occur in autoimmunity or transplantation, has the potential to alleviate many of the unwanted side effects associated with current immunosuppressiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5822ebd1e678f1abdd3dc49780864b8f
https://doi.org/10.1172/jci95914
https://doi.org/10.1172/jci95914
Autor:
Cynthia P. Breeden, Andrew B. Adams, Steven C. Kim, Abraham J. Matar, Brendan P. Lovasik, David A. Faber
Publikováno v:
Biology of Blood and Marrow Transplantation. 26:S259
Introduction Co-stimulation blockade (CoB) has emerged as a promising immunosuppression strategy and potential alternative to calcineurin inhibitors in solid organ transplantation. Despite recent advancements, CoB based regimens are hampered by incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfac94c1746d4c75f758779cd61057a5
https://doi.org/10.1016/j.bbmt.2019.12.454
https://doi.org/10.1016/j.bbmt.2019.12.454
Autor:
Maria E. Fuentes, Ying Dong, Christian P. Larsen, Cynthia P. Breeden, William H. Kitchens, Elizabeth Strobert, David V. Mathews, Mandy L. Ford, Andrew B. Adams
Publikováno v:
JCI Insight. 2
The potential of costimulation blockade to serve as a novel transplant immunosuppression strategy has been explored for over 20 years, culminating in the recent clinical approval of belatacept for renal transplant patients. Despite improving long-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb709b3bf1adf640d72fe8e923519f2
https://doi.org/10.1172/jci.insight.90317
https://doi.org/10.1172/jci.insight.90317
Fc-Silent Anti-CD154 Domain Antibody Effectively Prevents Nonhuman Primate Renal Allograft Rejection
Autor:
Christian P. Larsen, Anish Suri, Elizabeth Strobert, Aaron P. Yamniuk, Steven G. Nadler, Steven C. Kim, Thomas C. Pearson, Walter Wakwe, Cynthia P. Breeden, Robert Kuhn, Andrew B. Adams, Mandy L. Ford, Haiqing Wang, Joe B. Jenkins, Allison Stephenson, David V. Mathews, Karen Price, Suzanne J. Suchard, Laura B. Higginbotham, Alton B. Farris, Laura Price
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 17(5)
The advent of costimulation blockade provides the prospect for targeted therapy with improved graft survival in transplant patients. Perhaps the most effective costimulation blockade in experimental models is the use of reagents to block the CD40/CD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546e1839d6917c82f83978a0f72ad7e4
https://pubmed.ncbi.nlm.nih.gov/28141921
https://pubmed.ncbi.nlm.nih.gov/28141921
Autor:
Ying Dong, Joshua A. Albrecht, Jason Wang, Cynthia P. Breeden, Aron E. Lukacher, Alton B. Farris, Kenneth A. Newell
Publikováno v:
American Journal of Transplantation. 12:1419-1428
Nephropathy associated with BK polyomavirus (BKV) causes kidney allograft dysfunction and failure. Understanding the pathogenesis of polyomavirus-associated allograft nephropathy (PVAN) is hampered by the species specificity of Polyomaviridae family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf84b7ed91b70a4f2eb353915d5c88c5
https://doi.org/10.1111/j.1600-6143.2012.04005.x
https://doi.org/10.1111/j.1600-6143.2012.04005.x
Autor:
Alyson Swimm, Daniel Kalman, Jarad J. Wilson, Kenneth A. Newell, Aron E. Lukacher, Jun Wang, Ying Dong, Christopher D. Pack, Annette Hadley, Elizabeth L. Frost, Eugene Lin, Cynthia P. Breeden
Publikováno v:
Journal of Virology
Human polyomaviruses are associated with substantial morbidity in immunocompromised patients, including those with HIV/AIDS, recipients of bone marrow and kidney transplants, and individuals receiving immunomodulatory agents for autoimmune and inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0460e0f4478e5e79d19b8b4f1f6693d
Autor:
Joshua A. Albrecht, David V. Mathews, Andrew B. Adams, Steven C. Kim, Mandy L. Ford, Kenneth A. Newell, Jun Wang, Alton B. Farris, Aron E. Lukacher, Ying Dong, Cynthia P. Breeden
Publikováno v:
Transplantation Direct
Background The interplay between viral infection and alloimmunity is known to influence the fate of transplanted organs. Clarifying how local virus-associated inflammation/injury and antiviral immunity can alter host alloimmune responses in transplan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0672eca413f768a5d2c76908f863ed51
https://doi.org/10.1097/txd.0000000000000677
https://doi.org/10.1097/txd.0000000000000677
Autor:
Aneesh K. Mehta, Beth Begley, Prasad Mulupuri, Cynthia P. Breeden, Christian P. Larsen, Adam Popkowski, Rafi Ahmed, Tania Gourley
Publikováno v:
The FASEB Journal. 22:532-532
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::183be2190a24cbde9ff6d3e5a26d71f7
https://doi.org/10.1096/fasebj.22.2_supplement.532
https://doi.org/10.1096/fasebj.22.2_supplement.532