Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Cynthia M. Theodos"'
Autor:
Jay S. Markowitz, Michael J. Grusby, Richard G. Titus, Laurie H. Glimcher, Cynthia M. Theodos, Hrishekesh R. Chakkalath
Publikováno v:
Journal of Infectious Diseases. 171:1302-1308
Class II major histocompatibility complex (MHC)-deficient (H-2b) mice do not express I-A or I-E molecules and, as a result, do not develop CD4 cells. Thus, they represent the ideal model for examining the importance of CD4 cells and MHC class II mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59cb39bcf3c2d53d4ff27c7d42b1490c
https://doi.org/10.1093/infdis/171.5.1302
https://doi.org/10.1093/infdis/171.5.1302
Autor:
Anne E. Goldfeld, Erik K. Flemington, Cynthia M. Theodos, Richard G. Titus, Samuel H. Speck, Vicki A. Boussiotis, Jack L. Strominger
Publikováno v:
Proceedings of the National Academy of Sciences. 89:12198-12201
The human tumor necrosis factor alpha (TNF-alpha) gene encodes a cytokine whose activities have been implicated in many immunopathological processes, including the activation and differentiation of lymphocytes. Originally identified as a monocyte fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e427cca83427c8fdd9bbb1e887426445
https://doi.org/10.1073/pnas.89.24.12198
https://doi.org/10.1073/pnas.89.24.12198
Publikováno v:
Infection and Immunity. 59:2839-2842
Recombinant human tumor necrosis factor (TNF) and purified murine TNF were both able to activate macrophages to destroy intracellular Leishmania major in vitro. In addition, parasitizing macrophages with L. major markedly increased the ability of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2108b9885a6df0da6ce96ba96e95c079
https://doi.org/10.1128/iai.59.8.2839-2842.1991
https://doi.org/10.1128/iai.59.8.2839-2842.1991
Publikováno v:
Journal of clinical microbiology. 36(9)
Cryptosporidiosis is a serious disease in malnourished children and in people with malignancies or AIDS. Current rodent models for evaluating drug therapy against cryptosporidiosis have many limitations, including the need for a high inoculum, the ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2433882408cf1befd84c20ab533056b
https://pubmed.ncbi.nlm.nih.gov/9705383
https://pubmed.ncbi.nlm.nih.gov/9705383
Autor:
Jeffrey K. Griffiths, Saul Tzipori, Cynthia M. Theodos, Alexandra Fairfield, Jennifer D’Onfro
Publikováno v:
Antimicrobial agents and chemotherapy. 42(8)
Nitazoxanide (NTZ), a drug currently being tested in human clinical trials for efficacy against chronic cryptosporidiosis, was assessed in cell culture and in two animal models. The inhibitory activity of NTZ was compared with that of paromomycin (PR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4631acc0e1a2d5f762e4650faf700404
https://pubmed.ncbi.nlm.nih.gov/9687390
https://pubmed.ncbi.nlm.nih.gov/9687390
Publikováno v:
Infection and immunity. 65(11)
This study describes healing and nonhealing models of Cryptosporidium parvum infection with adult mice that have functional T and B lymphocytes. In our nonhealing model, mice on a C57BL/6 background which have a targeted disruption in the gamma inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b18d95b8be1f276fac61963796855a
https://pubmed.ncbi.nlm.nih.gov/9353062
https://pubmed.ncbi.nlm.nih.gov/9353062
Autor:
Anuraj H. Shankar, Andrew L. Glasebrook, Cynthia M. Theodos, William D. Roeder, Richard G. Titus
Publikováno v:
Parasite immunology. 16(11)
To assess the role of interleukin-1 (IL-1) in cutaneous leishmaniasis, Leishmania major-infected mice were treated with an anti-IL-1 receptor monoclonal antibody, LA-15.6. MoAb LA-15.6 prevents binding of IL-1 to both the T cell and B cell/macrophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28101acffd93a9febc58f6c68769d19e
https://pubmed.ncbi.nlm.nih.gov/7862463
https://pubmed.ncbi.nlm.nih.gov/7862463
Autor:
Richard G. Titus, Cynthia M. Theodos
Publikováno v:
Parasite immunology. 15(8)
Summary Previous work from our laboratory demonstrated that the infectivity of the protozoan parasite Leishmania major was enhanced in mice if the infecting inoculum contained salivary gland lysates from the sand fly vector Lutzomyia longipalpis. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69034b629eb8ae31bfe0e0effbad105d
https://pubmed.ncbi.nlm.nih.gov/8233563
https://pubmed.ncbi.nlm.nih.gov/8233563
Autor:
Paul B. Kimsey, Cynthia M. Theodos, Laura Povinelli, L R Hall, Anuraj H. Shankar, Richard G. Titus, Mary McGurn
Publikováno v:
Subcellular Biochemistry ISBN: 9781489916532
Members of the genus Leishmania are protozoan parasites that exist as flagellated promastigotes in the vector for the parasite, the phlebotomine sandfly. Man acquires the disease when bitten by an infected sandfly. The life cycle of Leishmania is sch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2582db16d18cb0b30913e89813d63400
https://doi.org/10.1007/978-1-4899-1651-8_4
https://doi.org/10.1007/978-1-4899-1651-8_4
