Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Cynthia M McMillen"'
Autor:
Trevor Griesman, Cynthia M McMillen, Seble Getenet Negatu, Jesse J Hulahan, Kanupriya Whig, Lenka Dohnalová, Mark Dittmar, Christoph A Thaiss, Kellie A Jurado, David C Schultz, Amy L Hartman, Sara Cherry
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012343 (2024)
Rift Valley fever virus (RVFV) is an encephalitic bunyavirus that can infect neurons in the brain. There are no approved therapeutics that can protect from RVFV encephalitis. Innate immunity, the first line of defense against infection, canonically a
Externí odkaz:
https://doaj.org/article/d221228f379b45f0b4778a0afb0e3282
Autor:
Douglas S Reed, Anita K McElroy, Dominique J Barbeau, Cynthia M McMillen, Natasha L Tilston-Lunel, Shamkumar Nambulli, Emily Cottle, Theron C Gilliland, Hasala Rannulu, Jeneveve Lundy, Emily L Olsen, Katherine J O'Malley, Mengying Xia, Amy L Hartman, Thomas C Luke, Kristi Egland, Christoph Bausch, Hua Wu, Eddie J Sullivan, William B Klimstra, W Paul Duprex
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0290909 (2024)
Since SARS-CoV-2 emerged in late 2019, it spread from China to the rest of the world. An initial concern was the potential for vaccine- or antibody-dependent enhancement (ADE) of disease as had been reported with other coronaviruses. To evaluate this
Externí odkaz:
https://doaj.org/article/e111baf91dfb4fc09c7205841d90cc09
Autor:
Cynthia M McMillen, Devin A Boyles, Stefan G Kostadinov, Ryan M Hoehl, Madeline M Schwarz, Joseph R Albe, Matthew J Demers, Amy L Hartman
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 10, p e0010898 (2022)
Rift Valley fever (RVF) is a disease of animals and humans associated with abortions in ruminants and late-gestation miscarriages in women. Here, we use a rat model of congenital RVF to identify tropisms, pathologies, and immune responses in the plac
Externí odkaz:
https://doaj.org/article/252dffdec9d24454814de48ee8408d52
Autor:
Henry Ma, Joseph R Albe, Theron Gilliland, Cynthia M McMillen, Christina L Gardner, Devin A Boyles, Emily L Cottle, Matthew D Dunn, Jeneveve D Lundy, Noah Salama, Katherine J O'Malley, Ivona Pandrea, Tobias Teichert, Stacey Barrick, William B Klimstra, Amy L Hartman, Douglas S Reed
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1009946 (2022)
Venezuelan equine encephalitis virus (VEEV) is a positively-stranded RNA arbovirus of the genus Alphavirus that causes encephalitis in humans. Cynomolgus macaques are a relevant model of the human disease caused by VEEV and are useful in exploring pa
Externí odkaz:
https://doaj.org/article/a9ae6f80485742ccbbc0ae30019f063d
Autor:
Joseph R Albe, Henry Ma, Theron H Gilliland, Cynthia M McMillen, Christina L Gardner, Devin A Boyles, Emily L Cottle, Matthew D Dunn, Jeneveve D Lundy, Katherine J O'Malley, Noah Salama, Aaron W Walters, Ivona Pandrea, Tobias Teichert, William B Klimstra, Douglas S Reed, Amy L Hartman
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009308 (2021)
Aerosol exposure to eastern equine encephalitis virus (EEEV) can trigger a lethal viral encephalitis in cynomolgus macaques which resembles severe human disease. Biomarkers indicative of central nervous system (CNS) infection by the virus and lethal
Externí odkaz:
https://doaj.org/article/148107b18d2d4b4295040268973f0ef0
Autor:
Amy L Hartman, Sham Nambulli, Cynthia M McMillen, Alexander G White, Natasha Louise Tilston-Lunel, Joseph R Albe, Emily Cottle, Matthew D Dunn, L James Frye, Theron H Gilliland, Emily L Olsen, Katherine J O'Malley, Madeline M Schwarz, Jaime A Tomko, Reagan C Walker, Mengying Xia, Matthew S Hartman, Edwin Klein, Charles A Scanga, JoAnne L Flynn, William B Klimstra, Anita K McElroy, Douglas S Reed, W Paul Duprex
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008903 (2020)
Vaccines are urgently needed to combat the global coronavirus disease 2019 (COVID-19) pandemic, and testing of candidate vaccines in an appropriate non-human primate (NHP) model is a critical step in the process. Infection of African green monkeys (A
Externí odkaz:
https://doaj.org/article/9af9b959abac4308b999b6e2d34961ea
Autor:
Joseph R Albe, Devin A Boyles, Aaron W Walters, Michael R Kujawa, Cynthia M McMillen, Douglas S Reed, Amy L Hartman
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007833 (2019)
Rift Valley fever virus (RVFV) causes severe disease in livestock concurrent with zoonotic transmission to humans. A subset of people infected with RVFV develop encephalitis, and significant gaps remain in our knowledge of how RVFV causes pathology i
Externí odkaz:
https://doaj.org/article/e0c25f150c4c4c20910536b32320f6cd
Autor:
John D Noti, Francoise M Blachere, Cynthia M McMillen, William G Lindsley, Michael L Kashon, Denzil R Slaughter, Donald H Beezhold
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57485 (2013)
BACKGROUND: The role of relative humidity in the aerosol transmission of influenza was examined in a simulated examination room containing coughing and breathing manikins. METHODS: Nebulized influenza was coughed into the examination room and Bioaero
Externí odkaz:
https://doaj.org/article/8d87c88f42dd4c349082866a78e07c2b
Autor:
Madeline M. Schwarz, Kaleigh A. Connors, Katherine A. Davoli, Cynthia M. McMillen, Joseph R. Albe, Ryan M. Hoehl, Matthew J. Demers, Safder S. Ganaie, David A. Price, Daisy W. Leung, Gaya K. Amarasinghe, Anita K. McElroy, Douglas S. Reed, Amy L. Hartman
Publikováno v:
Journal of virology. 96(20)
People infected with the mosquito-borne Rift Valley fever virus (RVFV) can suffer from eye-related problems resulting in ongoing vision issues or even permanent blindness. Despite ocular disease being the most frequently reported severe outcome, it i
Autor:
Cynthia M. McMillen, Devin A. Boyles, Stefan G. Kostadinov, Ryan M. Hoehl, Madeline M. Schwarz, Joseph R. Albe, Matthew J. Demers, Amy L. Hartman
Rift Valley fever (RVF) is a disease of animals and humans associated with abortions in ruminants and, more recently, late-gestation miscarriages in African women. Here, we use a rat model of congenital RVF to identify cellular tropism, pathology, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e01f781a370b3ba417fd9357e7ad963
https://doi.org/10.1101/2022.02.25.481831
https://doi.org/10.1101/2022.02.25.481831