Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Cynthia M, Hingtgen"'
Autor:
Staci Martin, Elizabeth K. Schorry, James H. Tonsgard, Heather L. Thompson, Pamela L. Wolters, Christopher J. Funes, Andrea Baldwin, Cynthia M. Hingtgen, Barbara Franklin, Stephanie Reeve, Taryn Allen, Taylor F. Smith, Kimberley S. Koetsier, Ana-Maria Vranceanu, Vanessa L. Merker, Carolina Barnett
Publikováno v:
Neurology
ObjectiveTo review and recommend patient-reported outcome (PRO) measures assessing multidimensional domains of quality of life (QoL) to use as clinical endpoints in medical and psychosocial trials for children and adults with neurofibromatosis (NF) t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ab0f25b7d57c1dabbd1583290477d2
https://doi.org/10.1212/wnl.0000000000012421
https://doi.org/10.1212/wnl.0000000000012421
Autor:
Pamela L, Wolters, Staci, Martin, Vanessa L, Merker, James H, Tonsgard, Sondra E, Solomon, Andrea, Baldwin, Amanda L, Bergner, Karin, Walsh, Heather L, Thompson, Kathy L, Gardner, Cynthia M, Hingtgen, Elizabeth, Schorry, William N, Dudley, Barbara, Franklin, Kaleb, Yohay
Publikováno v:
Neurology. 87:S4-S12
Objective: Tumors and other disease complications of neurofibromatosis (NF) can cause pain and negatively affect physical functioning. To document the clinical benefit of treatment in NF trials targeting these manifestations, patient-reported outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7083d532ffe74ab2b90a1a200417e1c
https://doi.org/10.1212/wnl.0000000000002927
https://doi.org/10.1212/wnl.0000000000002927
Autor:
Waylan K. Bessler, Brandon D. Downing, Kara N. Sarchet, Simon J. Conway, Lisa M. Kamendulis, Cynthia M. Hingtgen, Fang Li, D. Wade Clapp, Lucy C. Smiley, Daniel M. Hinds, Brian K. Stansfield, Jamie Case, David A. Ingram, Julie A. Mund, Matthew R. Distasi
Publikováno v:
Circulation. 129:1213-1224
Background— Neurofibromatosis type 1 (NF1) is a genetic disorder resulting from mutations in the NF1 tumor suppressor gene. Neurofibromin, the protein product of NF1 , functions as a negative regulator of Ras activity in circulating hematopoietic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8b99e31c23fc47cd080ce8366b0f2c
https://doi.org/10.1161/circulationaha.113.006320
https://doi.org/10.1161/circulationaha.113.006320
Publikováno v:
The Journal for Nurse Practitioners. 10:30-35
Von Recklinghausen or neurofibromatosis type 1 is an autosomal dominant condition that results in skin changes and noncancerous tumors along the nerves in the body. It is blind in regards to ethnicity, race, or sex. With a prevalence rate of 1 in 3,0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::235e1a93cd084bf4d935a007aaa7e38a
https://doi.org/10.1016/j.nurpra.2013.07.001
https://doi.org/10.1016/j.nurpra.2013.07.001
Autor:
James H. Tonsgard, Cynthia M. Hingtgen, Andrea Baldwin, Kathy Gardner, Elizabeth K. Schorry, Vanessa L. Merker, Pamela L. Wolters, Staci Martin
Publikováno v:
Neurology. 81:S6-S14
Objectives: Neurofibromatosis (NF) is a genetic disease with multiple clinical manifestations that can significantly impact quality of life (QOL). Clinical trials should include patient-reported outcomes (PROs) as endpoints to assess treatment effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc87b8c0851f1ab6fb1ccc9fee4da4cd
https://doi.org/10.1212/01.wnl.0000435747.02780.bf
https://doi.org/10.1212/01.wnl.0000435747.02780.bf
Publikováno v:
Neuroscience Letters. 496:70-74
Nerve growth factor (NGF) activates multiple downstream effectors, including Ras, phosphoinositide-3 kinase, and sphingomyelins. However, pathway mediating the NGF-induced augmentation of sensory neuronal excitability remains largely unknown. We prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2176110040b383996fdac66099367499
https://doi.org/10.1016/j.neulet.2011.03.083
https://doi.org/10.1016/j.neulet.2011.03.083
Autor:
Jill C. Fehrenbacher, Kellie A. Park, Cynthia M. Hingtgen, Djane B. Duarte, Eric L. Thompson, Michael R. Vasko
Publikováno v:
Neuroscience. 171:910-923
Nerve growth factor (NGF) can augment transmitter release in sensory neurons by acutely sensitizing sensory neurons and by increasing the expression of calcitonin gene-related peptide (CGRP) over time. The current study examined the intracellular sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94a29874366b24089c365a11fce36664
https://doi.org/10.1016/j.neuroscience.2010.09.027
https://doi.org/10.1016/j.neuroscience.2010.09.027
Publikováno v:
Neuroscience. 161:148-156
The glial cell line–derived neurotrophic factor (GDNF) family ligands (GFLs) are a group of peptides that have been implicated as important factors in inflammation, since they are released in increased amounts during inflammation and induce thermal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5960de2b1a6b6ccd081d73b6962da781
https://doi.org/10.1016/j.neuroscience.2009.03.006
https://doi.org/10.1016/j.neuroscience.2009.03.006
Autor:
Qiwei Zhang, Leslie A. Sitzman, Shanbao Cai, Cynthia M. Hingtgen, Mohammad Al-Hassani, Jeffrey B. Travers, Karen E. Pollok
Publikováno v:
Journal of Investigative Dermatology. 129(1):167-174
Ultraviolet B (UVB) radiation causes cutaneous inflammation. One important clinical consequence of UVB-induced inflammation is increased pain or hyperalgesia, which is likely mediated by enhanced sensitivity of cutaneous sensory neurons. Previous stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a5077708fc4c8ae6bae728ffe02202
Publikováno v:
The Laryngoscope. 117:917-922
Objective: Autologous muscle stem cell (myoblast) therapy may be an ideal treatment for vocal fold paralysis because of its technical ease (administered by injection), its potential to restore muscular defects and dynamic function, and its autologous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cddeb15a69104caaaa8648f575a60e
https://doi.org/10.1097/mlg.0b013e31803e8c8d
https://doi.org/10.1097/mlg.0b013e31803e8c8d