Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Cynthia Loomis"'
Autor:
Kristen L Lokken-Toyli, Surya D Aggarwal, Gavyn Chern Wei Bee, Wouter A A de Steenhuijsen Piters, Cindy Wu, Kenny Zhi Ming Chen, Cynthia Loomis, Debby Bogaert, Jeffrey N Weiser
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1012111 (2024)
Infants are highly susceptible to invasive respiratory and gastrointestinal infections. To elucidate the age-dependent mechanism(s) that drive bacterial spread from the mucosa, we developed an infant mouse model using the prevalent pediatric respirat
Externí odkaz:
https://doaj.org/article/db147eb912cc4567a3877fe5b6dfb2b6
Autor:
Rachel A. Prescott, Alec P. Pankow, Maren de Vries, Keaton M. Crosse, Roosheel S. Patel, Mark Alu, Cynthia Loomis, Victor Torres, Sergei Koralov, Ellie Ivanova, Meike Dittmann, Brad R. Rosenberg
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background The airway epithelium is composed of diverse cell types with specialized functions that mediate homeostasis and protect against respiratory pathogens. Human airway epithelial (HAE) cultures at air–liquid interface are a physiolo
Externí odkaz:
https://doaj.org/article/373f7a744e00421f9130874a55811427
Autor:
Maria G. Noval, Sophie N. Spector, Eric Bartnicki, Franco Izzo, Navneet Narula, Stephen T. Yeung, Payal Damani-Yokota, M. Zahidunnabi Dewan, Valeria Mezzano, Bruno A. Rodriguez-Rodriguez, Cynthia Loomis, Kamal M. Khanna, Kenneth A. Stapleford
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Chikungunya virus (CHIKV) infection has been associated with severe cardiac manifestations, yet, how CHIKV infection leads to heart disease remains unknown. Here, we leveraged both mouse models and human primary cardiac cells to define the m
Externí odkaz:
https://doaj.org/article/b75528f8101343d58a26fa2361f3e424
Autor:
Gregor Werba, Daniel Weissinger, Emily A. Kawaler, Ende Zhao, Despoina Kalfakakou, Surajit Dhara, Lidong Wang, Heather B. Lim, Grace Oh, Xiaohong Jing, Nina Beri, Lauren Khanna, Tamas Gonda, Paul Oberstein, Cristina Hajdu, Cynthia Loomis, Adriana Heguy, Mara H. Sherman, Amanda W. Lund, Theodore H. Welling, Igor Dolgalev, Aristotelis Tsirigos, Diane M. Simeone
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC) is a complex ecosystem that drives tumor progression; however, in-depth single cell characterization of the PDAC TME and its role in response to therapy is lacking.
Externí odkaz:
https://doaj.org/article/3a27bc68fbda40dca2027e7c95c28684
Autor:
Gregor Werba, Daniel Weissinger, Emily A. Kawaler, Ende Zhao, Despoina Kalfakakou, Surajit Dhara, Lidong Wang, Heather B. Lim, Grace Oh, Xiaohong Jing, Nina Beri, Lauren Khanna, Tamas Gonda, Paul Oberstein, Cristina Hajdu, Cynthia Loomis, Adriana Heguy, Mara H. Sherman, Amanda W. Lund, Theodore H. Welling, Igor Dolgalev, Aristotelis Tsirigos, Diane M. Simeone
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/fbf64e220d324d00ad2d20768841c89d
Autor:
Iris Scherwitzl, Silvana Opp, Alicia M. Hurtado, Christine Pampeno, Cynthia Loomis, Kasthuri Kannan, Minjun Yu, Daniel Meruelo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss , Pp 431-447 (2020)
Despite remarkable responses to cancer immunotherapy in a subset of patients, many patients remain resistant to therapies. It is now clear that elevated levels of tumor-infiltrating T cells as well as a systemic anti-tumor immune response are require
Externí odkaz:
https://doaj.org/article/75e61f4504cb4aaab669a71983399df6
Autor:
Alexandria J Hammond, Ulrike Binsker, Surya D Aggarwal, Mila Brum Ortigoza, Cynthia Loomis, Jeffrey N Weiser
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009158 (2021)
Binding of Streptococcus pneumoniae (Spn) to nasal mucus leads to entrapment and clearance via mucociliary activity during colonization. To identify Spn factors allowing for evasion of mucus binding, we used a solid-phase adherence assay with immobil
Externí odkaz:
https://doaj.org/article/d230cce3a6e3483ea2fe0a28d2481612
Autor:
Elham Vali-Betts, Kevin J Krause, Alanna Dubrovsky, Kristin Olson, John Paul Graff, Anupam Mitra, Ananya Datta-Mitra, Kenneth Beck, Aristotelis Tsirigos, Cynthia Loomis, Antonio Galvao Neto, Esther Adler, Hooman H Rashidi
Publikováno v:
Journal of Pathology Informatics, Vol 12, Iss 1, Pp 5-5 (2021)
Aims: Histology, the microscopic study of normal tissues, is a crucial element of most medical curricula. Learning tools focused on histology are very important to learners who seek diagnostic competency within this important diagnostic arena. Recent
Externí odkaz:
https://doaj.org/article/6c14c16e2ba54b69a13a0fb1dd43a478
Autor:
Daniel B. Rifkin, Michael Cammer, Cynthia Loomis, Kyuichi Kadota, Kotaro Shibahara, Victoria Fang, Masahito Horiguchi, Mitsuhiko Ota
PDF file - 185KB, A. Survival, B. Weight, C. Organ Weight/Body Weight, D. Spleen, E. Total TGFbeta1 Level (pg/ml), F. Active TGFbeta1 Level (pg/ml).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0556ec20a93fe31477ed0e90b6161e5
https://doi.org/10.1158/0008-5472.22401576.v1
https://doi.org/10.1158/0008-5472.22401576.v1
Autor:
Daniel B. Rifkin, Michael Cammer, Cynthia Loomis, Kyuichi Kadota, Kotaro Shibahara, Victoria Fang, Masahito Horiguchi, Mitsuhiko Ota
The contributions of TGF-β signaling to cancer are complex but involve the inflammatory microenvironment as well as cancer cells themselves. In mice encoding a TGF-β mutant that precludes its binding to the latent TGF-β binding protein (Tgfb1−/C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f50ae90b95b69c904bac4ec84d3bff79
https://doi.org/10.1158/0008-5472.c.6505887
https://doi.org/10.1158/0008-5472.c.6505887