Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cynthia L. Perreault"'
Autor:
Pamela S. Douglas, Thomas G. Hampton, Kerry E. Travers, Ian I Joffe, James P. Morgan, Cynthia L. Perreault-Micale, Sarah E. Katz
Publikováno v:
Journal of the American College of Cardiology. 34(7):2111-2119
OBJECTIVES We sought to evaluate in vivo and in vitro left ventricular (LV) geometry and function in streptozotocin-induced diabetic rats and the possible role of the nitric oxide (NO) pathway. BACKGROUND Diabetes results in cardiac dysfunction; howe
Publikováno v:
Journal of Muscle Research and Cell Motility. 17:533-542
ATPase activities of molluscan adductor muscle myosins show both muscle and species specific differences: ATPase activity of catch muscle myosin is lower than that of phasic muscle myosin; a 4-5-fold difference exists between the activities of phasic
Publikováno v:
European Journal of Pharmacology. 264:437-443
Endothelin is a potent vasoconstrictor and a positive inotropic agent in myocardium. Endothelin has been reported to increase myocardial contractility with little or no increase in intracellular Ca2+, thus apparently enhancing myofilament responsiven
Publikováno v:
Cardiovascular Research. 27:262-268
Objective: Cocaine produces both vascular and myocardial effects that can lead to serious cardiovascular complications in man. Tissue catecholamine stores are known to be depleted in the advanced stages of heart failure. The effects of cocaine on car
Autor:
Malcolm F. Sim, Ian M. Hunneyball, Evan Loh, James P. Morgan, Nancy L. Hague, Cynthia L. Perreault
Publikováno v:
British Journal of Pharmacology. 106:511-516
1. In right ventricular papillary muscles from control ferrets, flosequinan (10(-7)-10(-4) M) produced a concentration-dependent positive inotropic effect (10(-5) M = 153 +/- 24, 10(-4) M = 198 +/- 44% increase in isometric tension; control tension =
Autor:
Maria Del Carmen Garcia, H. Gonzalez-Serratos, J. P. Morgan, Cynthia L. Perreault, Monika Rozycka
Publikováno v:
Journal of Muscle Research and Cell Motility. 12:412-424
In fatigued muscles the T-system is swollen; thus the action potential may fail to travel along the T-system or the T-tubule terminal cisternae signal may fail to bring about TC Ca2+ release. This would lead to a decrease in the number of myofibrils
Publikováno v:
American Heart Journal. 121:961-968
Changes in cytoplasmic levels of free-ionized calcium regulate the contraction and relaxation of cardiac and vascular smooth muscle. Aside from changing the intrinsic rate of energy use within the cell, an intervention that alters the strength of con
Publikováno v:
British Journal of Pharmacology. 101:679-685
1. When ferret right ventricular papillary muscles were stimulated with threshold punctate pulses (0.33 Hz; 30 degrees C), cocaine, 10(-5) M, increased peak tension development from 815 +/- 120 to 1125 +/- 180 mg (P less than 0.05) and increased the
Autor:
David Allen, Susan Duty, H?kan Westerblad, H. Gonzalez-Serratos, Monika Rozycka, J. P. Morgan, Cynthia L. Perreault
Publikováno v:
Journal of Muscle Research and Cell Motility. 14:543-545
Publikováno v:
European journal of pharmacology. 399(2-3)
Phospholipase A 2 plays a crucial role in the release of arachidonic acid (AA) from membrane phospholipids and in myocardial injury during ischemia and reperfusion. Mepacrine, a phospholipase A 2 inhibitor, has been shown to protect the heart from is