Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Cynthia L. Henry"'
Autor:
Noah Tu, Kennan C. Marsh, Karl W. Mollison, Rolf Wagner, Gin C. Hsieh, Cynthia L. Henry, Merrill Nuss, Jay R. Luly, Denise Wilcox, Nwe Y. Bamaung, Benjamin C. Lane, Richard P. Carlson, Yung-Wu Chen, Thomas A. Fey, Luping Liu, Paul E. Wiedeman, Yat-Sun Or, James M. Trevillyan, George W. Carter, Peer B. Jacobson, Teresa A. Rosenberg, Stevan W. Djuric
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:5340-5343
The synthesis and biological activities of rapamycin (I) analogs modified at the C-40 position are reported. Emphasis placed on compounds that potentially have an improved safety profile on account of their shorter in vivo half-life when compared wit
Autor:
Karl W. Mollison, Thomas A. Fey, Donna M. Gauvin, Michael P. Sheets, Morey L. Smith, Melissa Pong, Ruth Krause, Loan Miller, Yat Sun Or, Megumi Kawai, Rolf Wagner, Paul E. Wiedeman, Richard F. Clark, Indrani W. K. Gunawardana, Teresa A. Rhoades, Cynthia L. Henry, Noah P. Tu, Nwe Y. BaMaung, Hana Kopecka, Luping Liu, Qinghua Xie, Benjamin C. Lane, James M. Trevillyan, Kennan Marsh, George W. Carter, Yung-Wu Chen, Gin C. Hsieh, Jay R. Luly
Publikováno v:
Current Pharmaceutical Design. 4:367-379
Abstract: Drug therapy for the major inflammatory skin diseases, which include atopic dermatitis, psoriasis and allergic contact dermatitis, is often inadequate due to poor efficacy, toxicity, or both. Much research has focused on the macrolactam T c
Autor:
Cynthia L. Henry, Marvin M. Hansen, Benjamin Alan Anderson, Jeffrey Thomas Vicenzi, Milton J. Zmijewski, Harkness Allen Robert
Publikováno v:
Journal of the American Chemical Society. 117:12358-12359