Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Cynthia L David"'
Autor:
Monika Wysocka-Kapcinska, Beata Torocsik, Lilla Turiak, George Tsaprailis, Cynthia L David, Andrea M Hunt, Karoly Vekey, Vera Adam-Vizi, Roza Kucharczyk, Christos Chinopoulos
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74187 (2013)
The ADP/ATP carrier protein (AAC) expressed in Artemia franciscana is refractory to bongkrekate. We generated two strains of Saccharomyces cerevisiae where AAC1 and AAC3 were inactivated and the AAC2 isoform was replaced with Artemia AAC containing a
Externí odkaz:
https://doaj.org/article/f097ba8f46ff43ef9ec2d7360b8b2377
Autor:
Sini Sunny, Arun Jyothidasan, Cynthia L. David, Krishna Parsawar, Arul Veerappan, Dean P. Jones, Steven Pogwizd, Namakkal S. Rajasekaran
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Nuclear factor erythroid 2-related factor 2 (NRF2), a redox sensor, is vital for cellular redox homeostasis. We reported that transgenic mice expressing constitutively active Nrf2 (CaNrf2-TG) exhibit reductive stress (RS). In this study, we identifie
Externí odkaz:
https://doaj.org/article/6f46c3b363dc403288078fd580f7ae56
Autor:
Pamela A. Zobel-Thropp, Jennifer Mullins, Charles Kristensen, Brent A. Kronmiller, Cynthia L. David, Linda A. Breci, Greta J. Binford
Publikováno v:
Frontiers in Ecology and Evolution, Vol 7 (2019)
Pholcid spiders (Araneae: Pholcidae), officially “cellar spiders” but popularly known as “daddy long-legs,” are renown for the potential of deadly toxic venom, even though venom composition and potency has never formally been studied. Here we
Externí odkaz:
https://doaj.org/article/60a1689010f44b80b06621e4d6f4a3f4
Autor:
Sini Sunny, Cynthia L David, Krishna Parsawar, Steven pogwizd, Rajasekaran N Namakkal-Soorappan
Publikováno v:
Circulation Research. 131
Background: A real-time action of Nrf2 in response to a stress is vital to preserve the redox homeostasis, but its activation under unstressed settings tilt the redox balance towards the reductive arm, leading to reductive stress (RS). In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d22200e847ae3dcfb2cfefc00cf5ab90
https://doi.org/10.1161/res.131.suppl_1.p2045
https://doi.org/10.1161/res.131.suppl_1.p2045
Nuclear factor erythroid 2-related factor 2 (NRF2), a redox sensor, is vital for cellular redox homeostasis. We reported that transgenic mice expressing constitutively active Nrf2 (CaNrf2-TG) exhibit reductive stress (RS). In this study, we identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::215eedbdd7d5af2b0455dbb9a6f0d24f
https://doi.org/10.1101/2021.09.13.460105
https://doi.org/10.1101/2021.09.13.460105
Autor:
Pamela A, Zobel-Thropp, Jennifer, Mullins, Charles, Kristensen, Brent A, Kronmiller, Cynthia L, David, Linda A, Breci, Greta J, Binford
Publikováno v:
Frontiers in ecology and evolution
Pholcid spiders (Araneae: Pholcidae), officially “cellar spiders” but popularly known as “daddy long-legs,” are renown for the potential of deadly toxic venom, even though venom composition and potency has never formally been studied. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06391449c7c4e1a5a923eee734de28f7
https://pubmed.ncbi.nlm.nih.gov/33235882
https://pubmed.ncbi.nlm.nih.gov/33235882
Autor:
Ke-Wei Zhao, Samuel S. Murray, Elisa Atti, Cynthia L. David, M. Eugenia L. Duarte, Haijun Tian, Elsa J. Brochmann, Chenshuang Li, Jeffrey C. Wang, Kevin Phan
Publikováno v:
Journal of Cellular Biochemistry. 116:667-676
Secreted phosphoprotein 24 kD (spp24) is a bone matrix protein isolated during attempts to identify osteogenic proteins. It is not osteogenic but performs other important roles in the regulation of bone metabolism, at least in part, by binding to and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6772adffc0bcad839b38a4e264fd02ea
https://doi.org/10.1002/jcb.25023
https://doi.org/10.1002/jcb.25023
Autor:
Rahul Purohit, Bradley G. Fritz, Juliana The, Aaron Issaian, Andrzej Weichsel, Cynthia L. David, Eric Campbell, Andrew C. Hausrath, Leida Rassouli-Taylor, Elsa D. Garcin, Matthew J. Gage, William R. Montfort
Publikováno v:
Biochemistry. 53:101-114
Soluble guanylate cyclase (sGC) is a heterodimeric heme protein and the primary nitric oxide receptor. NO binding stimulates cyclase activity, leading to regulation of cardiovascular physiology and making sGC an attractive target for drug discovery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5d7ee8178441ad304370392c34a2c9
https://doi.org/10.1021/bi4015133
https://doi.org/10.1021/bi4015133
Autor:
Cynthia L. David, Manping X. Liu, Thomas J. Turbyville, A. A. Leslie Gunatilaka, Anna M. Burns, Libia A. Luevano, E. M. Kithsiri Wijeratne, Luke Whitesell, C.J. Seliga, Stanley H. Faeth
Publikováno v:
Journal of Natural Products. 69:178-184
In an effort to discover small molecule inhibitors of Hsp90, we have screened over 500 EtOAc extracts of Sonoran desert plant-associated fungi using a two-stage strategy consisting of a primary cell-based heat shock induction assay (HSIA) followed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15a5b82a5e78e9ab46ca5506571c74a8
https://doi.org/10.1021/np058095b
https://doi.org/10.1021/np058095b
Publikováno v:
Radiology. 231:52-56
A 66-year-old man was found to be anemic and thrombocytopenic during his annual physical examination. Work-up with bone marrow evaluation revealed mild marrow fibrosis with marked megakaryocytic hyperplasia, a finding that is consistent with early my
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808823214e5f91abd262d47e0b7aee05
https://doi.org/10.1148/radiol.2311020673
https://doi.org/10.1148/radiol.2311020673