Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Cynthia L Darnell"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 1, p e1011115 (2024)
Timely regulation of carbon metabolic pathways is essential for cellular processes and to prevent futile cycling of intracellular metabolites. In Halobacterium salinarum, a hypersaline adapted archaeon, a sugar-sensing TrmB family protein controls gl
Externí odkaz:
https://doaj.org/article/362b84a28a6c47408fb7e8de14b2a2d4
Autor:
Peter D Tonner, Cynthia L Darnell, Francesca M L Bushell, Peter A Lund, Amy K Schmid, Scott C Schmidler
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1008366 (2020)
Substantive changes in gene expression, metabolism, and the proteome are manifested in overall changes in microbial population growth. Quantifying how microbes grow is therefore fundamental to areas such as genetics, bioengineering, and food safety.
Externí odkaz:
https://doaj.org/article/bfd34c3824224212846d9bc76d435aaf
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Halobacterium salinarum are halophilic archaea that display directional swimming in response to various environmental signals, including light, chemicals and oxygen. In Hbt. salinarum, the building blocks (archaellins) of the archaeal swimming appara
Externí odkaz:
https://doaj.org/article/d342a1d1201549a588c899bf2ec71c1a
Autor:
Saaz Sakrikar, Rylee K. Hackley, Mar Martinez-Pastor, Cynthia L. Darnell, Angie Vreugdenhil, Amy K. Schmid
Publikováno v:
mBio. 14
Most cells in eukaryotic species—from yeast to humans—possess histone proteins that pack and unpack DNA in response to environmental cues. These essential proteins regulate genes necessary for important cellular processes, including development a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaa0206ad3dbd69a112c2f831bf29523
https://doi.org/10.1128/mbio.03449-22
https://doi.org/10.1128/mbio.03449-22
Autor:
Saaz Sakrikar, Rylee K. Hackley, Mar Martinez-Pastor, Cynthia L. Darnell, Angie Vreugdenhil, Amy K. Schmid
DNA-binding proteins with roles in chromatin architecture and transcriptional regulation are present in all three domains of life. Histones package DNA and regulate gene expression in eukaryotes, and find their evolutionary origin in the domain of li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f510cf1441f7b2bdb1e0f455d5395ad8
https://doi.org/10.1101/2022.03.22.485428
https://doi.org/10.1101/2022.03.22.485428
Autor:
Cynthia L, Darnell, Jenny, Zheng, Sean, Wilson, Ryan M, Bertoli, Alexandre W, Bisson-Filho, Ethan C, Garner, Amy K, Schmid
Publikováno v:
mBio
Healthy cell growth and division are critical for individual organism survival and species long-term viability. However, it remains unknown how cells of the domain Archaea maintain a healthy cell cycle. Understanding the archaeal cell cycle is of par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98365de19ba72d80a1a51ddc4e9f4106
https://pubmed.ncbi.nlm.nih.gov/32788376
https://pubmed.ncbi.nlm.nih.gov/32788376
Autor:
Alexandre W. Bisson-Filho, Sean M. Wilson, Ethan C. Garner, Jenny Zheng, Cynthia L. Darnell, Amy K. Schmid, Ryan M. Bertoli
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
Precise control of the cell cycle is central to the physiology of all cells. In prior work we demonstrated that archaeal cells maintain a constant size; however, the regulatory mechanisms underlying the cell cycle remain unexplored in this domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189c60b9e87a72e89b1402ac363ce522
https://journals.asm.org/doi/10.1128/mBio.01007-20
https://journals.asm.org/doi/10.1128/mBio.01007-20
Autor:
Ethan C. Garner, Sean M. Wilson, Ryan M. Bertoli, Jenny Zheng, Alexandre W. Bisson-Filho, Amy K. Schmid, Cynthia L. Darnell
Precise control of the cell cycle is central to the physiology of all cells. In prior work we demonstrated that archaeal cells maintain a constant size; however, the regulatory mechanisms underlying the cell cycle remain unexplored in this domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9bbd5d5aa25efe9bdd83b636adbe824
https://doi.org/10.1101/2020.06.16.153114
https://doi.org/10.1101/2020.06.16.153114
Autor:
Peter A. Lund, Francesca M.L. Bushell, Cynthia L. Darnell, Scott C. Schmidler, Peter D. Tonner, Amy K. Schmid
Substantive changes in gene expression, metabolism, and the proteome are manifested in overall changes in microbial population growth. Quantifying how microbes grow is therefore fundamental to areas such as genetics, bioengineering, and food safety.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b267f74b10f8a9dd4c5c5daf94d87e18
https://doi.org/10.1101/793174
https://doi.org/10.1101/793174
Publikováno v:
Microbial Genomics
Genomic instability, although frequently deleterious, is also an important mechanism for microbial adaptation to environmental change. Although widely studied in bacteria, in archaea the effect of genomic instability on organism phenotypes and fitnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1facb44420c80f469f1c1f3aa5990e79
https://doi.org/10.1099/mgen.0.000210
https://doi.org/10.1099/mgen.0.000210