Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Cynthia L, Darnell"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 1, p e1011115 (2024)
Timely regulation of carbon metabolic pathways is essential for cellular processes and to prevent futile cycling of intracellular metabolites. In Halobacterium salinarum, a hypersaline adapted archaeon, a sugar-sensing TrmB family protein controls gl
Externí odkaz:
https://doaj.org/article/362b84a28a6c47408fb7e8de14b2a2d4
Autor:
Saaz Sakrikar, Rylee K. Hackley, Mar Martinez-Pastor, Cynthia L. Darnell, Angie Vreugdenhil, Amy K. Schmid
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Histone proteins are found across diverse lineages of Archaea, many of which package DNA and form chromatin. However, previous research has led to the hypothesis that the histone-like proteins of high-salt-adapted archaea, or halophiles, fun
Externí odkaz:
https://doaj.org/article/a4187bde4b9b4b7db7785a08bc9b4fbd
Autor:
Peter D Tonner, Cynthia L Darnell, Francesca M L Bushell, Peter A Lund, Amy K Schmid, Scott C Schmidler
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1008366 (2020)
Substantive changes in gene expression, metabolism, and the proteome are manifested in overall changes in microbial population growth. Quantifying how microbes grow is therefore fundamental to areas such as genetics, bioengineering, and food safety.
Externí odkaz:
https://doaj.org/article/bfd34c3824224212846d9bc76d435aaf
Autor:
Cynthia L. Darnell, Jenny Zheng, Sean Wilson, Ryan M. Bertoli, Alexandre W. Bisson-Filho, Ethan C. Garner, Amy K. Schmid
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Precise control of the cell cycle is central to the physiology of all cells. In prior work we demonstrated that archaeal cells maintain a constant size; however, the regulatory mechanisms underlying the cell cycle remain unexplored in this d
Externí odkaz:
https://doaj.org/article/efe91ec2cd5b4204ab3646133fe6130f
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Halobacterium salinarum are halophilic archaea that display directional swimming in response to various environmental signals, including light, chemicals and oxygen. In Hbt. salinarum, the building blocks (archaellins) of the archaeal swimming appara
Externí odkaz:
https://doaj.org/article/d342a1d1201549a588c899bf2ec71c1a
Publikováno v:
mSystems, Vol 2, Iss 5 (2017)
ABSTRACT Gene regulatory networks (GRNs) are critical for dynamic transcriptional responses to environmental stress. However, the mechanisms by which GRN regulation adjusts physiology to enable stress survival remain unclear. Here we investigate the
Externí odkaz:
https://doaj.org/article/3bbdaf3a09eb4d9082a1bd61dc3fcd72
Autor:
Saaz Sakrikar, Rylee K. Hackley, Mar Martinez-Pastor, Cynthia L. Darnell, Angie Vreugdenhil, Amy K. Schmid
DNA-binding proteins with roles in chromatin architecture and transcriptional regulation are present in all three domains of life. Histones package DNA and regulate gene expression in eukaryotes, and find their evolutionary origin in the domain of li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f510cf1441f7b2bdb1e0f455d5395ad8
https://doi.org/10.1101/2022.03.22.485428
https://doi.org/10.1101/2022.03.22.485428
Autor:
Alexandre W. Bisson-Filho, Sean M. Wilson, Ethan C. Garner, Jenny Zheng, Cynthia L. Darnell, Amy K. Schmid, Ryan M. Bertoli
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
Precise control of the cell cycle is central to the physiology of all cells. In prior work we demonstrated that archaeal cells maintain a constant size; however, the regulatory mechanisms underlying the cell cycle remain unexplored in this domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189c60b9e87a72e89b1402ac363ce522
https://journals.asm.org/doi/10.1128/mBio.01007-20
https://journals.asm.org/doi/10.1128/mBio.01007-20
Autor:
Ethan C. Garner, Sean M. Wilson, Ryan M. Bertoli, Jenny Zheng, Alexandre W. Bisson-Filho, Amy K. Schmid, Cynthia L. Darnell
Precise control of the cell cycle is central to the physiology of all cells. In prior work we demonstrated that archaeal cells maintain a constant size; however, the regulatory mechanisms underlying the cell cycle remain unexplored in this domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9bbd5d5aa25efe9bdd83b636adbe824
https://doi.org/10.1101/2020.06.16.153114
https://doi.org/10.1101/2020.06.16.153114
Autor:
Peter A. Lund, Francesca M.L. Bushell, Cynthia L. Darnell, Scott C. Schmidler, Peter D. Tonner, Amy K. Schmid
Substantive changes in gene expression, metabolism, and the proteome are manifested in overall changes in microbial population growth. Quantifying how microbes grow is therefore fundamental to areas such as genetics, bioengineering, and food safety.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b267f74b10f8a9dd4c5c5daf94d87e18
https://doi.org/10.1101/793174
https://doi.org/10.1101/793174