Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cynthia J. Long"'
Autor:
Ollie W. Press, Zhongli Ding, Morikazu Miura, Ashutosh Chilkoti, Cynthia J. Long, Niren Murthy, Nobuo Monji, Allan S. Hoffman, Patrick S. Stayton, Katsuhiko Nakamae, John H. Priest, Robin B. Fong, Takashi Nishino, Chuck Cheung, Sara G. Shoemaker, Jingping Chen, Heung Joon Yang, Carole Ann Cole, Takashi Miyata, Chantal Lackey, Robert C. Nowinski, Volga Bulmus, John E. Morris, Tsuyoshi Shimoboji, Guohua Chen, Yoshikuni Nabeshima, Tae Gwan Park, Liang-chang Dong, J. Milton Harris
Publikováno v:
Journal of Biomedical Materials Research. 52:577-586
Over the past 18 years we have been deeply involved with the synthesis and applications of stimuli-responsive polymer systems, especially polymer-biomolecule conjugates. This article summarizes our work with one of these conjugate systems, specifical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35b9c1924911eb1cca01a824a86858a9
https://doi.org/10.1002/1097-4636(20001215)52:4<577::aid-jbm1>3.0.co
https://doi.org/10.1002/1097-4636(20001215)52:4<577::aid-jbm1>3.0.co
Autor:
Patrick S. Stayton, Zhongli Ding, Allan S. Hoffman, Esma V. Bulmus, Cynthia J. Long, Yoshiki Hayashi
Publikováno v:
Bioconjugate Chemistry. 10:395-400
The many laboratory and diagnostic applications utilizing streptavidin as a molecular adaptor rely on its high affinity and essentially irreversible interaction with biotin. However, there are many situations where recovery of the biotinylated molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25837e010868cde661f2ef2306180cd
https://doi.org/10.1021/bc980108s
https://doi.org/10.1021/bc980108s
Publikováno v:
Toxicon. 31:85-90
This study explores human immunodeficiency virus 1 (HIV-1)-regulated diphtheria toxin A (DT-A) gene expression as a means of eradicating HIV-infected cells. Previously, we constructed luciferase and DT-A plasmids, containing cis-acting Tat and Rev re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c718d2a5d1d77ad8cca5263d0a1de788
https://doi.org/10.1016/0041-0101(93)90360-u
https://doi.org/10.1016/0041-0101(93)90360-u
Autor:
L. Michael Glode, Françoise Maxwell, Cynthia J. Long, Ian H. Maxwell, Gail S. Harrison, Craig A. Rosen
Publikováno v:
Human Gene Therapy. 2:53-60
Expression of a gene encoding the diphtheria toxin A (DT-A) fragment, controlled by tissue specific regulatory elements, has previously been used to kill selected cell populations. Here, we have examined the feasibility of controlling DT-A expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d794d50e9758646864f315bba8b70f
https://doi.org/10.1089/hum.1991.2.1-53
https://doi.org/10.1089/hum.1991.2.1-53
Autor:
Allan S. Hoffman, Patrick S. Stayton, J. M. Harris, Tsuyoshi Shimoboji, Ashutosh Chilkoti, Cynthia J. Long, Guohua Chen
Publikováno v:
Nature. 378:472-474
Stimuli-responsive polymers exhibit reversible phase changes in response to changes in environmental factors such as pH or temperature. Conjugating such polymers to antibodies and proteins provides molecular systems for applications such as affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f1fac47d4cc814b41ff33acd95cf6a
https://doi.org/10.1038/378472a0
https://doi.org/10.1038/378472a0
Publikováno v:
Nature. 411(6833)
Many medical and biotechnological processes rely on controlling and manipulating the molecular-recognition capabilities of proteins1,2,3,4. This can be achieved using small molecules capable of competing for protein binding or by changing environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d144928b094ff275f1fc4ccdc35f37
https://pubmed.ncbi.nlm.nih.gov/11333975
https://pubmed.ncbi.nlm.nih.gov/11333975
Publikováno v:
Bioconjugate chemistry. 11(1)
Low molecular weight copolymers of acrylic acid (AAc) and N-isopropylacrylamide (NIPAAm) have been synthesized with reactive OH groups at one end, using a chain transfer polymerization technique. The copolymer displays both pH and temperature sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba2d949a5e56c73653a96e0a4aa66ad
https://pubmed.ncbi.nlm.nih.gov/10639089
https://pubmed.ncbi.nlm.nih.gov/10639089
Publikováno v:
Bioconjugate chemistry. 10(5)
A versatile strategy has been developed for selectively and sequentially isolating targets in a liquid-phase affinity separation environment. The strategy uses a recently developed approach for joining together molecules in linkages that are defined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4f0c16be8b15f50cc5a543d4a137b8
https://pubmed.ncbi.nlm.nih.gov/10502336
https://pubmed.ncbi.nlm.nih.gov/10502336
Publikováno v:
Bio/technology (Nature Publishing Company). 13(11)
We report the construction of chimeric streptavidin tetramers that are composed of subunits of both wild-type (WT) streptavidin and genetically-engineered streptavidin variants designed for enhanced bioseparation and drug delivery performance. Subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7ab5e34b2428c37c6c30fb053dd419
https://pubmed.ncbi.nlm.nih.gov/9678918
https://pubmed.ncbi.nlm.nih.gov/9678918
Publikováno v:
The Journal of general virology. 74
We previously constructed a recombinant LuIII parvovirus genome lacking viral coding sequences and used it to generate luciferase-transducing virions, by co-transfection of cells with a helper plasmid expressing LuIII viral proteins. Here, we describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56421690059b9e86632a47159807d24c
https://pubmed.ncbi.nlm.nih.gov/8509766
https://pubmed.ncbi.nlm.nih.gov/8509766