Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Cynthia J. Balog-Alvarez"'
Autor:
Sara Mata López, James J. Hammond, Madison B. Rigsby, Cynthia J. Balog-Alvarez, Joe N. Kornegay, Peter P. Nghiem
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-6 (2018)
Abstract Background Boys with Duchenne muscular dystrophy (DMD) have DMD gene mutations, with associated loss of the dystrophin protein and progressive muscle degeneration and weakness. Corticosteroids and palliative support are currently the best tr
Externí odkaz:
https://doaj.org/article/eb783a37156645ac8356d2e5603c7c91
Autor:
Muhammad Abdullah, Joe N. Kornegay, Aubree Honcoop, Traci L. Parry, Cynthia J. Balog-Alvarez, Sara K. O’Neal, James R. Bain, Michael J. Muehlbauer, Christopher B. Newgard, Cam Patterson, Monte S. Willis
Publikováno v:
Metabolites, Vol 7, Iss 3, p 38 (2017)
Background: Like Duchenne muscular dystrophy (DMD), the Golden Retriever Muscular Dystrophy (GRMD) dog model of DMD is characterized by muscle necrosis, progressive paralysis, and pseudohypertrophy in specific skeletal muscles. This severe GRMD pheno
Externí odkaz:
https://doaj.org/article/c780cc0b649e4ce59daf058b4b4e5c58
Autor:
Paul T Martin, Deborah A Zygmunt, Anna Ashbrook, Sonia Hamilton, Davin Packer, Sharla M Birch, Amanda K Bettis, Cynthia J Balog-Alvarez, Lee-Jae Guo, Peter P Nghiem, Joe N Kornegay
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248721 (2021)
We have examined the effects of intravenous (IV) delivery of rAAVrh74.MHCK7.GALGT2 in the golden retriever muscular dystrophy (GRMD) model of Duchenne Muscular Dystrophy (DMD). After baseline testing, GRMD dogs were treated at 3 months of age and rea
Externí odkaz:
https://doaj.org/article/8daea8ae30e441fc877a6ae566d3dfd6
Autor:
Jessica R Terrill, Basma A Al-Mshhdani, Marisa N Duong, Catherine D Wingate, Zahra Abbas, Angelo P Baustista, Amanda K Bettis, Cynthia J Balog-Alvarez, Joe N Kornegay, Peter P Nghiem, Miranda D Grounds, Peter G Arthur
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240317 (2020)
Duchenne muscular dystrophy (DMD) is a lethal, X-chromosome linked muscle-wasting disease affecting about 1 in 3500-6000 boys worldwide. Myofibre necrosis and subsequent loss of muscle mass are due to several molecular sequelae, such as inflammation
Externí odkaz:
https://doaj.org/article/eae05b71b57444cfbe0f2f0026f1357c
Autor:
Sharla M. Birch, Michael W. Lawlor, Thomas J. Conlon, Lee-Jae Guo, Julie M. Crudele, Eleanor C. Hawkins, Peter P. Nghiem, Mihye Ahn, Hui Meng, Margaret J. Beatka, Brittany A. Fickau, Juan C. Prieto, Martin A. Styner, Michael J. Struharik, Courtney Shanks, Kristy J. Brown, Diane Golebiowski, Amanda K. Bettis, Cynthia J. Balog-Alvarez, Nathalie Clement, Kirsten E. Coleman, Manuela Corti, Xiufang Pan, Stephen D. Hauschka, J. Patrick Gonzalez, Carl A. Morris, Joel S. Schneider, Dongsheng Duan, Jeffrey S. Chamberlain, Barry J. Byrne, Joe. N. Kornegay
Publikováno v:
Science translational medicine. 15(677)
Duchenne muscular dystrophy (DMD) is a progressive muscle wasting disease caused by the absence of dystrophin, a membrane-stabilizing protein encoded by the DMD gene. Although mouse models of DMD provide insight into the potential of a corrective the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286334212cdab7cd1ec6f09084ab2d3f
https://pubmed.ncbi.nlm.nih.gov/36599002
https://pubmed.ncbi.nlm.nih.gov/36599002
Autor:
Cynthia J. Balog-Alvarez, Joe N. Kornegay, Sara Mata López, Kristy J. Brown, Peter P. Nghiem, Stanislav Vitha, Emily H. Canessa, Yetrib Hathout, Jessica F. Boehler, Amanda K. Bettis
Publikováno v:
Mammalian Genome. 31:95-109
The availability of an in vitro canine cell line would reduce the need for dogs for primary in vitro cell culture and reduce overall cost in pre-clinical studies. An immortalized canine muscle cell line, named Myok9, from primary myoblasts of a norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a3bdaa285220877fe03e8f3fd1c72e
https://doi.org/10.1007/s00335-020-09833-5
https://doi.org/10.1007/s00335-020-09833-5
Autor:
Peter G. Arthur, Miranda D. Grounds, Peter P. Nghiem, Basma A. Al-Mshhdani, Catherine D. Wingate, Jessica R. Terrill, Marisa N. Duong, Joe N. Kornegay, Amanda K. Bettis, Zahra Abbas, Angelo P. Baustista, Cynthia J. Balog-Alvarez
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0240317 (2020)
PLoS ONE, Vol 15, Iss 10, p e0240317 (2020)
Duchenne muscular dystrophy (DMD) is a lethal, X-chromosome linked muscle-wasting disease affecting about 1 in 3500-6000 boys worldwide. Myofibre necrosis and subsequent loss of muscle mass are due to several molecular sequelae, such as inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94cc3f508363b88fbec022d2e54d395e
http://europepmc.org/articles/PMC7544076
http://europepmc.org/articles/PMC7544076
Autor:
Cynthia J. Balog-Alvarez, Mary B. Nabity, Xue Yu, Joe N. Kornegay, Candice Chu, Candice Brinkmeyer-Langford, James J. Cai
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236916 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0194485.].
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e31184414094d68644931cb16ccc2be
https://doaj.org/article/0415a00950a44777bff18f01a68545ab
https://doaj.org/article/0415a00950a44777bff18f01a68545ab
Autor:
Sara Mata López, Amanda K. Bettis, Emily H. Canessa, Cynthia J. Balog-Alvarez, Joe N. Kornegay, Stanislav Vitha, Peter P. Nghiem
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241430 (2020)
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0228072 (2020)
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0228072 (2020)
Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene that abolish the expression of dystrophin protein. Dogs with the genetic homologue, golden retriever muscular dystrophy dog (GRMD), have a splice site mutation that leads to ski
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0926a1b79582e11d4d18b1916f80c6c
https://doaj.org/article/b1443758b0054829b4f1522d684c93d4
https://doaj.org/article/b1443758b0054829b4f1522d684c93d4
Autor:
Peter P. Nghiem, Sara Mata López, Madison B. Rigsby, James J. Hammond, Joe N. Kornegay, Cynthia J. Balog-Alvarez
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-6 (2018)
Skeletal Muscle
Skeletal Muscle
Background Boys with Duchenne muscular dystrophy (DMD) have DMD gene mutations, with associated loss of the dystrophin protein and progressive muscle degeneration and weakness. Corticosteroids and palliative support are currently the best treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4669c99ca748bb4ba834002e634355ff
http://link.springer.com/article/10.1186/s13395-018-0162-1
http://link.springer.com/article/10.1186/s13395-018-0162-1