Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cynthia Guy"'
Autor:
Tianyi Chen, George Dalton, Seh-Hoon Oh, Raquel Maeso-Diaz, Kuo Du, Rachel A. Meyers, Cynthia Guy, Manal F. Abdelmalek, Ricardo Henao, Paolo Guarnieri, Steven S. Pullen, Simon Gregory, Joseph Locker, J. Mark Brown, Anna Mae Diehl
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 4, Pp 949-970 (2023)
Background & Aims: Nonalcoholic steatohepatitis (NASH), a leading cause of cirrhosis, strongly associates with the metabolic syndrome, an insulin-resistant proinflammatory state that disrupts energy balance and promotes progressive liver degeneration
Externí odkaz:
https://doaj.org/article/9a1fec7762f04ba181df024b17ce1685
Autor:
Kara Wegermann, Marat Fudim, Ricardo Henao, Catherine F. Howe, Robert McGarrah, Cynthia Guy, Manal F. Abdelmalek, Anna Mae Diehl, Cynthia A. Moylan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 14 (2023)
Background Nonalcoholic fatty liver disease (NAFLD) and heart failure with preserved ejection fraction (HFpEF) share common risk factors, including obesity and diabetes. They are also thought to be mechanistically linked. The aim of this study was to
Externí odkaz:
https://doaj.org/article/b039730bdfb84d48a651f270b0cc3361
Autor:
George M Philips, Isaac S Chan, Marzena Swiderska, Vanessa T Schroder, Cynthia Guy, Gamze F Karaca, Cynthia Moylan, Talaignair Venkatraman, Sebastian Feuerlein, Wing-Kin Syn, Youngmi Jung, Rafal P Witek, Steve Choi, Gregory A Michelotti, Fatima Rangwala, Elmar Merkle, Christopher Lascola, Anna Mae Diehl
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e23943 (2011)
Chronic fibrosing liver injury is a major risk factor for hepatocarcinogenesis in humans. Mice with targeted deletion of Mdr2 (the murine ortholog of MDR3) develop chronic fibrosing liver injury. Hepatocellular carcinoma (HCC) emerges spontaneously i
Externí odkaz:
https://doaj.org/article/16dd751bd6f9486994806d16ba3f85eb
Autor:
Marybeth A. Nedrud, Mohammad Chaudhry, Michael S. Middleton, Cynthia A. Moylan, Reginald Lerebours, Sheng Luo, Alfredo Farjat, Cynthia Guy, Rohit Loomba, Manal F. Abdelmalek, Claude B. Sirlin, Mustafa R. Bashir
Publikováno v:
Radiology. 306
Background Several early-phase clinical trials for the treatment of nonalcoholic steatohepatitis (NASH) use liver fat content as measured with the MRI-derived proton density fat fraction (PDFF) for a primary outcome. These trials have shown relative
Autor:
Tianyi Chen, George Dalton, Seh-Hoon Oh, Raquel Maeso-Diaz, Kuo Du, Rachel A. Meyers, Cynthia Guy, Manal F. Abdelmalek, Ricardo Henao, Paolo Guarnieri, Steven S. Pullen, Simon Gregory, Joseph Locker, J. Mark Brown, Anna Mae Diehl
Publikováno v:
Cellular and molecular gastroenterology and hepatology.
Nonalcoholic steatohepatitis (NASH), a leading cause of cirrhosis, strongly associates with the Metabolic Syndrome (MetS), an insulin-resistant pro-inflammatory state that disrupts energy balance and promotes progressive liver degeneration. We aimed
Autor:
Rohit Loomba, Sudha Shankar, Katherine Yates, Clayton Dehn, James Bolognese, Brent Tetri, Kris Kowdley, Raj Vuppalanchi, Cynthia Guy, James Tonascia, Anthony Samir, Claude Sirlin, Sarah Sherlock, Kathryn Fowler, Helen Heymann, Tania Kamphaus, Roberto Calle, Arun Sanyal
Publikováno v:
Journal of Hepatology. 77:S451-S452
Autor:
Elizabeth M. Brunt, Andrew D. Clouston, Zachary Goodman, Cynthia Guy, David E. Kleiner, Carolin Lackner, Dina G. Tiniakos, Aileen Wee, Matthew Yeh, Wei Qiang Leow, Elaine Chng, Yayun Ren, George Goh Boon Bee, Elizabeth E. Powell, Mary Rinella, Arun J. Sanyal, Brent Neuschwander-Tetri, Zobair Younossi, Michael Charlton, Vlad Ratziu, Stephen A. Harrison, Dean Tai, Quentin M. Anstee
Publikováno v:
Journal of Hepatology
Histologically assessed hepatocyte ballooning is a key feature discriminating non-alcoholic steatohepatitis (NASH) from steatosis (NAFL). Reliable identification underpins patient inclusion in clinical trials and serves as a key regulatory-approved s
Autor:
Luong Ruiz, Tian Lan, Wenhui Liu, Amir Ashique, Harry Chen, Jiping Zha, Alex DePaoli, Igor Mikaelian, Cynthia Guy, Eugenia Henry, William Chang, Corinne Foo-Atkins, Hsiao Lieu
Publikováno v:
Journal of Hepatology. 77:S486
Autor:
Tian Lan, Luong Ruiz, Wenhui Liu, Amir Ashique, Harry Chen, Jiping Zha, Alex DePaoli, Igor Mikaelian, Cynthia Guy, Eugenia Henry, Corinne Foo-Atkins, William Chang, Hsiao Lieu
Publikováno v:
Journal of Hepatology. 77:S443
Autor:
Stephen A. Harrison, Guy Neff, Cynthia Guy, Mustafa Bashir, Angelo Paredes, Juan Frias, Ziad H. Younes, James F. Trotter, Nadege T. Gunn, Sam Moussa, Anita Kohli, Kristen Nelson, Mildred Gottwald, William Chang, Andrew Yan, Alex Depaoli, Lei Ling, Hsiao Lieu
Publikováno v:
Journal of Hepatology. 73:S114-S115