Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Cynthia Gallant"'
Autor:
Eliza J. Morris, Jeffrey R. Moore, Cynthia Gallant, Kathleen G. Morgan, David A. Weitz, Mikkel H. Jensen
Publikováno v:
Biophysical Journal. 106(4):793-800
The actin-binding protein calponin has been previously implicated in actin cytoskeletal regulation and is thought to act as an actin stabilizer, but the mechanism of its function is poorly understood. To investigate this underlying physical mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a875b2cc1e89c9893ea589f85b2188c
Autor:
Julie L. Hodgkinson, Cynthia Gallant, Mohammed El-Mezgueldi, Jeffrey R. Moore, Sarah Appel, Thomas E. Angelini, Mikkel H. Jensen, James Watt, Kathleen G. Morgan, William Lehman
Publikováno v:
Cytoskeleton. 69:49-58
The cellular actin cytoskeleton plays a central role in the ability of cells to properly sense, propagate, and respond to external stresses and other mechanical stimuli. Calponin, an actin-binding protein found both in muscle and non-muscle cells, ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f7418fbd02f12e0d78cc6e14a88e08
https://doi.org/10.1002/cm.20548
https://doi.org/10.1002/cm.20548
Autor:
Cynthia Gallant, Samudra S. Gangopadhyay, Eric J. Sundberg, Kathleen G. Morgan, William S. Lane
Publikováno v:
Biochemical Journal. 412:507-516
Ca2+/ Calmodulin (CaM)-dependent protein kinase II (CaMKII) is a ubiquitous protein that has numerous functions in fundamental cellular processes including metabolism, cell cycle control [1], cell shape variation, gene transcription [2] and the regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c21da45700523325376adf2fd809df
https://doi.org/10.1042/bj20071582
https://doi.org/10.1042/bj20071582
Autor:
S. Munevar, B. Colombo, F.W. Sellke, Samudra S. Gangopadhyay, Cynthia Gallant, Kathleen G. Morgan
Publikováno v:
Journal of Cellular and Molecular Medicine
CaMKII is a calcium and calmodulin-activated kinase that has been shown to regulate learning and memory in the brain, and contractility in blood vessels. Following Ca activation, CaMKII autophosphorylates, gaining a calcium-independent autonomous act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdd1e40ae1facef4256d91ea22ace7c
https://doi.org/10.1111/j.1582-4934.2007.00202.x
https://doi.org/10.1111/j.1582-4934.2007.00202.x
Publikováno v:
Journal of Cellular Biochemistry. 100:129-140
In late pregnancy rapidly increasing fetal growth dramatically increases uterine wall tension. This process has been implicated in the activation of the myometrium for labor, but the mechanisms involved are unclear. Here, we tested, using a rat model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64d8a7d35098e3f4a90f2f60e08e4e9
https://doi.org/10.1002/jcb.21033
https://doi.org/10.1002/jcb.21033
Autor:
Kathleen G. Morgan, Cynthia Gallant, Hyun-Dong Je, William A. Marganski, Samudra S. Gangopadhyay
Publikováno v:
Circulation Research. 97:541-549
Subcellular targeting of kinases controls their activation and access to substrates. Although Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) is known to regulate differentiated smooth muscle cell (dSMC) contractility, the importance of target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11893434070b534dcc953acbfab6e0c4
https://doi.org/10.1161/01.res.0000182630.29093.0d
https://doi.org/10.1161/01.res.0000182630.29093.0d
Autor:
Cynthia Gallant, Kathleen G. Morgan, Amy L. Barber, Samudra S. Gangopadhyay, Janet L. Smith, Zenon Grabarek
Publikováno v:
Biochemical Journal. 372:347-357
Six variants of calmodulin-dependent protein kinase IIγ were isolated from a ferret-aorta smooth-muscle cDNA library. Variant G-2 is generated by a novel alternative polyadenylation, utilizing a site contained in an intron. The last 77 residues of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c155e4c209f653a875d0e3b475466121
https://doi.org/10.1042/bj20030015
https://doi.org/10.1042/bj20030015
Autor:
David J. Hartshorne, Cynthia Gallant, Heung-Mook Shin, Hyun-Dong Je, Terence Tao, Kathleen G. Morgan, Masaaki Ito
Publikováno v:
Circulation Research. 90:546-553
It has been known for some time that agonist-induced contractions of vascular smooth muscle are often associated with a sensitization of the contractile apparatus to intracellular Ca 2+ . One mechanism that has been suggested to explain Ca 2+ sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f3117589da1fb0743d638c2bd19446b
https://doi.org/10.1161/01.res.0000012822.23273.ec
https://doi.org/10.1161/01.res.0000012822.23273.ec
Publikováno v:
Journal of Biological Chemistry. 275:3213-3220
To assess the functional significance of tethering actin to myosin by caldesmon in the regulation of smooth muscle contraction, we investigated the effects of synthetic peptides, containing the myosin-binding sequences in the N-terminal region of cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a10a2de010be60d8d66cac223a146f4
https://doi.org/10.1074/jbc.275.5.3213
https://doi.org/10.1074/jbc.275.5.3213
Autor:
Sandeep Gupta, Irwin Goldstein, Stone Yang, Cynthia Gallant, Abdulmaged M. Traish, Robert B. Moreland
Publikováno v:
British Journal of Pharmacology. 123:1237-1245
1. The purpose of this study was to determine if corpus cavernosum smooth muscle expresses functional postsynaptic alpha2-adrenoceptors (AR). 2. The alpha2-adrenoceptor agonist UK 14,304 elicited concentration-dependent contractions in rabbit corpus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81e38b4fd013a0b401db3e1a9b693b98
https://doi.org/10.1038/sj.bjp.0701739
https://doi.org/10.1038/sj.bjp.0701739