Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Cynthia D. Timmers"'
Autor:
Lu Han, Yongxia Wu, Kun Fang, Sean Sweeney, Ulyss K. Roesner, Melodie Parrish, Khushbu Patel, Tom Walter, Julia Piermattei, Anthony Trimboli, Julia Lefler, Cynthia D. Timmers, Xue-Zhong Yu, Victor X. Jin, Michael T. Zimmermann, Angela J. Mathison, Raul Urrutia, Michael C. Ostrowski, Gustavo Leone
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Cancer-associated fibroblasts (CAFs) are the main component of the stroma in pancreatic cancer, but their tissue of origin remains to be defined. Here the authors perform lineage tracing and single cell RNA sequencing in mice and suggest the splanchn
Externí odkaz:
https://doaj.org/article/f4eb874301cd413b8b8363efaf0dfe69
Autor:
Katie A. Thies, Matthew W. Cole, Rachel E. Schafer, Jonathan M. Spehar, Dillon S. Richardson, Sarah A. Steck, Manjusri Das, Arthur W. Lian, Alo Ray, Reena Shakya, Sue E. Knoblaugh, Cynthia D. Timmers, Michael C. Ostrowski, Arnab Chakravarti, Gina M. Sizemore, Steven T. Sizemore
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
Abstract Background Breast cancer (BC) is the most common cancer in women and the leading cause of cancer-associated mortality in women. In particular, triple-negative BC (TNBC) has the highest rate of mortality due in large part to the lack of targe
Externí odkaz:
https://doaj.org/article/986a2f2be5dc406fa9d8fb78e612f5b5
Autor:
Hannah M. Knochelmann, Joshua D. Horton, Sixue Liu, Kent Armeson, John M. Kaczmar, Megan M. Wyatt, Mary S. Richardson, Shirley H. Lomeli, Ying Xiong, Evan M. Graboyes, Eric J. Lentsch, Joshua D. Hornig, Judith Skoner, Seth Stalcup, Maria V. Spampinato, Elizabeth Garrett-Mayer, Elizabeth C. O’Quinn, Cynthia D. Timmers, Martin J. Romeo, John M. Wrangle, M. Rita I. Young, Mark P. Rubinstein, Terry A. Day, Roger S. Lo, Chrystal M. Paulos, David M. Neskey
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100426- (2021)
Summary: Oral cavity squamous cell carcinoma (OCSCC) is a prevalent surgically treated subset of head and neck cancer with frequent recurrence and poor survival. Immunotherapy has demonstrated efficacy in recurrent/metastatic head and neck cancer. Ho
Externí odkaz:
https://doaj.org/article/106d0eef51b345229c78936aef78ee40
Autor:
Gregory B. Lesinski, Denis C. Guttridge, Tanios Bekaii-Saab, Mark Bloomston, Jennifer M. Maskarinec, Priyani Rajasekera, Cynthia D. Timmers, Zheng Che, Omar Elnaggar, Gregory S. Young, Alton B. Farris, Matthew R. Farren, Thomas A. Mace, Jennifer Yang, Erin E. Talbert
Supplementary Material contains Supplementary Figures 1-5 and Supplementary Table 1. Supplementary Figure 1. MEK162 treatment prevents cancer-induced weight loss and muscle wasting. Supplementary Figure 2. Development of a MEK162 resistant C-26 tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f58f079406240b5229b3033b34a7a14
https://doi.org/10.1158/1535-7163.22503772
https://doi.org/10.1158/1535-7163.22503772
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
LKB1 is a commonly mutated tumor suppressor in non–small cell lung cancer that exerts complex effects on signal transduction and transcriptional regulation. To better understand the downstream impact of loss of functional LKB1, we developed a trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2f699616c0aad34b539ebd484056c11
https://doi.org/10.1158/0008-5472.c.6508526.v1
https://doi.org/10.1158/0008-5472.c.6508526.v1
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
Supporting information including gene correlation matrix for LKB1 loss signature genes and additional drug sensitivity analyses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f8aebd91069ff28dd200f1d101d521
https://doi.org/10.1158/0008-5472.22412822.v1
https://doi.org/10.1158/0008-5472.22412822.v1
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
Reported LKB1 mutations in cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d80c38f96a2adea96156d58b6d94365
https://doi.org/10.1158/0008-5472.22412813
https://doi.org/10.1158/0008-5472.22412813
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
Regression associations between LKB1 loss signature and inhibitors in GDSC, CTRP, and CCLE studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d953e21de81df5e279e60feea3013f5
https://doi.org/10.1158/0008-5472.22412810
https://doi.org/10.1158/0008-5472.22412810
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
Gene expression data for resected lung adenocarcinomas and cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6203610ab91f0f5ffa680510f67caf
https://doi.org/10.1158/0008-5472.22412807.v1
https://doi.org/10.1158/0008-5472.22412807.v1
Autor:
David P. Carbone, Joseph M. Amann, Cynthia D. Timmers, Kyungho Park, Tadaaki Yamada, Jacob M. Kaufman
Mutational information for cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b66dab7c3a995fa594e2f31e003fdf0
https://doi.org/10.1158/0008-5472.22412816.v1
https://doi.org/10.1158/0008-5472.22412816.v1