Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cynthia D. Bradshaw"'
Autor:
Krishna M. Ella, Kathryn E. Meier, April E. Wisehart-Johnson, Anthony F. McNair, Angela C. S. Gore, Katrina C. Gause, Linda G. Jones, Eric L. Finley, Cynthia D. Bradshaw
Publikováno v:
Cellular Signalling. 10:415-426
High doses of propranolol inhibit phosphatidate phosphohydrolase (PAP) activity in intact cells, thus blocking metabolism of phosphatidic acid (PA), product of the phospholipase D (PLD) reaction. Vasopressin and phorbol ester activate PLD and ERK (ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6789209284478067203eef2609ea7bdf
https://doi.org/10.1016/s0898-6568(97)00140-x
https://doi.org/10.1016/s0898-6568(97)00140-x
Autor:
Krishna M. Ella, Kathryn E. Meier, Terra C. Gibbs, Jin Hyouk Park, Cynthia D. Bradshaw, David W. Shirley, Chen Qi
Publikováno v:
Journal of Cellular Physiology. 174:261-272
Phospholipase D (PLD) is activated in mammalian cells in response to a variety of growth factors and may play a role in cell proliferation. Lysophosphatidic acid (LPA) is a bioactive metabolite potentially generated as a result of PLD activation. Two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c38a6ac05554ae7a8e88be696ff5b0c4
https://doi.org/10.1002/(sici)1097-4652(199802)174:2<261::aid-jcp13>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199802)174:2<261::aid-jcp13>3.0.co
Publikováno v:
IUBMB Life. 40:709-719
Neutral sphingomyelinase (SMase)1 can be activated by extracellular signals to produce ceramide, which may affect mitogen-activated protein kinase (MAPK) activities. Neutral SMase activity was assessed in membranes from Jurkat, a human T-cell line, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41da40c68ff9432ada21a1bde80c26e3
https://doi.org/10.1080/15216549600201313
https://doi.org/10.1080/15216549600201313
Autor:
Krishna M. Ella, Linda G. Jones, Manashi Dey, April E. Wisehart-Johnson, Katrina C. Gause, Kathryn E. Meier, Cynthia D. Bradshaw, Eric C. Spivey
Publikováno v:
Journal of Biological Chemistry. 269:23790-23799
Activation of mitogen-activated protein kinases (MAPKs) was examined in the A7r5 rat vascular smooth muscle cell line. Treatment of A7r5 cells with vasopressin, phorbol ester (PMA), or serum resulted in activation of two MAPKs, Erk-1 and Erk-2. Phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea7359137735447ae43807a4b0729483
https://doi.org/10.1016/s0021-9258(17)31585-5
https://doi.org/10.1016/s0021-9258(17)31585-5
Autor:
Kathryn E. Meier, Chen Qi, Cynthia D. Bradshaw, April E. Wisehart-Johnson, Heather M. Sansbury, Krishna M. Ella
Publikováno v:
Immunology letters. 53(2-3)
The effects of phorbol 12-myristate 13-acetate (PMA) on the activities of phospholipase D (PLD3), mitogen-activated protein kinase (ERK), and c-Jun N-terminal kinase (JNK) were studied in Jurkat, a human T cell line, and EL4, a murine T-cell line. PM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1dddcc401d76e49a713ed59dda8ad4
https://pubmed.ncbi.nlm.nih.gov/9024981
https://pubmed.ncbi.nlm.nih.gov/9024981
Autor:
Kathryn E. Meier, Cynthia D. Bradshaw, Maria G. Buse, Stewart M. Knoepp, April E. Wisehart-Johnson, Krishna M. Ella
Publikováno v:
The Journal of biological chemistry. 271(3)
Regulation of the activity of the extracellular signal regulated kinase (ERK) mitogen-activated protein kinases was examined in Rat-1 HIR, a fibroblast cell line overexpressing the human insulin receptor. Insulin or phorbol ester induced partial acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945a64b64a674da4cb43d7493525c239
https://pubmed.ncbi.nlm.nih.gov/8576169
https://pubmed.ncbi.nlm.nih.gov/8576169
Autor:
Kathryn E. Meier, Eric C. Spivey, G.P. Meier, Krishna M. Ella, Cynthia D. Bradshaw, Kim M. Huffman
Publikováno v:
Analytical biochemistry. 218(1)
Phospholipase D (PLD) is activated in mammalian cells in response to a wide variety of stimuli. A rapid assay for agonist-activated PLD activity in cell extracts was developed, utilizing a fluorescent derivative of phosphatidylcholine as substrate. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4dafddfe0b86514dd662931e71c9559
https://pubmed.ncbi.nlm.nih.gov/8053546
https://pubmed.ncbi.nlm.nih.gov/8053546