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pro vyhledávání: '"Cynthia Crul"'
Autor:
Cynthia Crul, Annemieke van der Wal, Hanneke de Kort, Cees van Kooten, Emile de Heer, Nicole Schlagwein, Jan A. Bruijn, Annelein M. Stax
Publikováno v:
Transplantation, 94(9), 903-910
BACKGROUND Allogeneic islets of Langerhans transplantation is hampered in its success as a curative treatment of type 1 diabetes by the absence of potent, specific, and nontoxic immunosuppressive drugs. Here, we assessed whether donor bone marrow-der
Autor:
Cynthia Crul, Andrea M. Woltman, Sylvia W.A. Kamerling, Reinier N. van der Geest, Cees van Kooten, Annelein M. Stax, Nicole Schlagwein
Publikováno v:
Molecular Immunology. 45:2641-2650
Dendritic cells (DC) play an important role in immune responses and have been studied extensively in human and mouse models. CD40 triggering of DC has a pivotal role in their maturation process, obtaining the unique capacity to induce strong CD4 and