Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Cynthia Berlinicke"'
Autor:
Weifeng Li, Cynthia Berlinicke, Yinyin Huang, Stefanie Giera, Anna G. McGrath, Weixiang Fang, Chaoran Chen, Felipe Takaesu, Xiaoli Chang, Yukan Duan, Dinesh Kumar, Calvin Chang, Hai-Quan Mao, Guoqing Sheng, James C. Dodge, Hongkai Ji, Stephen Madden, Donald J. Zack, Xitiz Chamling
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106156- (2023)
Summary: Promoting myelination capacity of endogenous oligodendrocyte precursor cells (OPCs) is a promising therapeutic approach for CNS demyelinating disorders such as Multiple Sclerosis (MS). To aid in the discovery of myelination-promoting compoun
Externí odkaz:
https://doaj.org/article/84e544c0e3584673bb73309824fd116b
Autor:
July Carolina Romero, Cynthia Berlinicke, Sharon Chow, Yukan Duan, Yifei Wang, Xitiz Chamling, Lena Smirnova
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2023)
IntroductionOligodendrocytes (OLs) are the myelin-forming cells of the central nervous system (CNS). Although OLs can be differentiated from human-induced pluripotent stem cells (hiPSCs), the in vitro modeling of axon myelination in human cells remai
Externí odkaz:
https://doaj.org/article/39cdfcf8b2e34b2da0846c3a85a265e6
Autor:
Karl J. Wahlin, Jie Cheng, Shawna L. Jurlina, Melissa K. Jones, Nicholas R. Dash, Anna Ogata, Nawal Kibria, Sunayan Ray, Kiara C. Eldred, Catherine Kim, Jacob S. Heng, Jenny Phillips, Robert J. Johnston, David M. Gamm, Cynthia Berlinicke, Donald J. Zack
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Human pluripotent stem cells (PSCs) represent a powerful tool to investigate human eye development and disease. When grown in 3D, they can self-assemble into laminar organized retinas; however, variation in the size, shape and composition of individu
Externí odkaz:
https://doaj.org/article/9163c7a815ae44529b224062f12f13fe
Autor:
Liyun Zhang, Conan Chen, Jie Fu, Brendan Lilley, Cynthia Berlinicke, Baranda Hansen, Ding Ding, Guohua Wang, Tao Wang, Daniel Shou, Ying Ye, Timothy Mulligan, Kevin Emmerich, Meera T Saxena, Kelsi R Hall, Abigail V Sharrock, Carlene Brandon, Hyejin Park, Tae-In Kam, Valina L Dawson, Ted M Dawson, Joong Sup Shim, Justin Hanes, Hongkai Ji, Jun O Liu, Jiang Qian, David F Ackerley, Baerbel Rohrer, Donald J Zack, Jeff S Mumm
Publikováno v:
eLife, Vol 10 (2021)
Retinitis pigmentosa (RP) and associated inherited retinal diseases (IRDs) are caused by rod photoreceptor degeneration, necessitating therapeutics promoting rod photoreceptor survival. To address this, we tested compounds for neuroprotective effects
Externí odkaz:
https://doaj.org/article/ae361e62a3fd4acc8161a7ed3eae9011
Autor:
Saritha Tantravedi, Farhad Vesuna, Paul T. Winnard, Jr., Allison Martin, Michael Lim, Charles G. Eberhart, Cynthia Berlinicke, Eric Raabe, Paul J. van Diest, Venu Raman
Publikováno v:
Translational Oncology, Vol 12, Iss 1, Pp 96-105 (2019)
Medulloblastoma is the most common malignant tumor that arises from the cerebellum of the central nervous system. Clinically, medulloblastomas are treated by surgery, radiation, and chemotherapy, all of which result in toxicity and morbidity. Recent
Externí odkaz:
https://doaj.org/article/d6b70f7db6ee4f89a55ae33c6c6dc599
Autor:
Sophie Lambard, Sacha Reichman, Cynthia Berlinicke, Marie-Laure Niepon, Olivier Goureau, José-Alain Sahel, Thierry Léveillard, Donald J Zack
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13075 (2010)
RdCVF and RdCVF2, encoded by the nucleoredoxin-like genes NXNL1 and NXNL2, are trophic factors with therapeutic potential that are involved in cone photoreceptor survival. Studying how their expression is regulated in the retina has implications for
Externí odkaz:
https://doaj.org/article/9479dc390cb64115aafd29069b661187
Autor:
Qi Huang, Bohao Tang, July Carolina Romero, Yuqian Yang, Saifeldeen Khalil Elsayed, Gayatri Pahapale, Tien-Jung Lee, Itzy E. Morales Pantoja, Fang Han, Cynthia Berlinicke, Terry Xiang, Mallory Solazzo, Thomas Hartung, Zhao Qin, Brian S. Caffo, Lena Smirnova, David H. Gracias
Publikováno v:
Science advances. 8(33)
Brain organoids are important models for mimicking some three-dimensional (3D) cytoarchitectural and functional aspects of the brain. Multielectrode arrays (MEAs) that enable recording and stimulation of activity from electrogenic cells are widely ut
Autor:
Amit K Patel, Xin Duan, Mai T. Vu, Cynthia Berlinicke, Cassidy D. Lee, Karl J. Wahlin, Vance Lemmon, Santiago Vilar, Vinod Jaskula-Ranga, Hassan Al-Ali, Yang Hu, Tianlun Lu, Anna La Torre, Risa M. Broyer, Derek S. Welsbie, Katherine L. Mitchell, Donald J. Zack, Mikaela Louie, John L. Bixby, Robert N. Weinreb
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Axonal injury plays a major role in many neurodegenerative diseases. The dual leucine zipper kinase (DLK) signaling pathway is a key regulator of axonal injury-induced neuronal cell death; however, DLK also has an important role in promo
Autor:
Lili Xie, Ling-Ping Cen, Yiqing Li, Hui-Ya Gilbert, Oleksandr Strelko, Cynthia Berlinicke, Mihaela A. Stavarache, Madeline Ma, Yongting Wang, Qi Cui, Michael G. Kaplitt, Donald J. Zack, Larry I. Benowitz, Yuqin Yin
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Although mammalian retinal ganglion cells (RGCs) normally cannot regenerate axons nor survive after optic nerve injury, this failure is partially reversed by inducing sterile inflammation in the eye. Infiltrative myeloid cells express the axogenic pr
Autor:
Weifeng Li, Cynthia Berlinicke, Yinyin Huang, Weixiang Fang, Celeste Chen, Felipe Takaesu, Xiaoli Chang, Yukan Duan, Calvin Chang, Hai-Quan Mao, Guoqing Sheng, Stefanie Giera, James C. Dodge, Hongkai Ji, Stephen Madden, Donald J. Zack, Xitiz Chamling
Promoting myelination capacity of endogenous oligodendrocyte precursor cells (OPCs) is a promising therapeutic approach for central nervous system demyelinating disorders such as Multiple Sclerosis (MS). To aid in the discovery of myelination promoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3969605f502f401895dde8cebd67a1f0
https://doi.org/10.1101/2022.01.18.476755
https://doi.org/10.1101/2022.01.18.476755