Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Cynthia Be Chee"'
Autor:
Cynthia BE Chee
Publikováno v:
International Journal of Infectious Diseases, Vol 130, Iss , Pp S44-S45 (2023)
Mycobacterium tuberculosis complex (MTBC), the causative organisms of tuberculosis (TB), has afflicted man for millennia. TB was declared a global health emergency by the World Health Organization in 1993. Before the 2020 Covid pandemic, it was respo
Externí odkaz:
https://doaj.org/article/f915bf6fae914152a08aa24c9eefc32f
Autor:
Rick Twee-Hee Ong, Yijun Lin, Peiling Yap, Vanessa W Lim, Phoebe Lee, Yi Roe Tan, Mei Xuan Tan, Lydia Wenxin Lin, Cynthia BE Chee, Timothy Barkham, Mark Chen
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
Objectives WHO recommends that low burden countries consider systematic screening and treatment of latent tuberculosis infection (LTBI) in migrants from high incidence countries. We aimed to determine LTBI prevalence and risk factors and evaluate cos
Externí odkaz:
https://doaj.org/article/57292f7c5ac84f0682e9b22fff5f04d1
Publikováno v:
The International Journal of Tuberculosis and Lung Disease. 25:31-35
BACKGROUND: Adipokines are emerging mediators of immune response, and may affect susceptibility to active TB.OBJECTIVE: To examine the associations between adipokines and the risk of active TB.METHODS: In a case-control study nested within a prospect
Autor:
Rick Twee-Hee Ong, Vernon J. Lee, Yee Tang Wang, Leo Kang Yang Lim, Li Yang Hsu, Cynthia B.E. Chee, Li Hwei Sng
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases. 40:1079-1083
There were 290 multidrug-resistant (MDR)-TB cases diagnosed in Singapore from 2006 to 2018. Eighty-one percent were foreign-born. Spoligotyping and MIRU-VNTR methods identified 108 patients in 24 clusters. The Beijing spoligotype accounted for 22 clu
Autor:
Chen Bai, Jia Mei Hong, Tuan Zea Tan, Alvin Dingyuan Wang, Paul A. Tambyah, Suay Hong Gan, Hoi Wah She, Alicia Tay, Catherine W.M. Ong, Felicia Teo, Josephine Lum, Yu Wang, Amit Singhal, Andres F. Vallejo, Marta E Polak, Yee Tang Wang, Nicholas I. Paton, Qing Hao Miow, Cynthia B.E. Chee, Paul T. Elkington, Jon S. Friedland, Hong Rong Loh, Ying Ding
Publikováno v:
J Clin Invest
BACKGROUND: Matrix metalloproteinases (MMPs) are key regulators of tissue destruction in tuberculosis (TB) and may be targets for host-directed therapy. We conducted a phase II double-blind, randomized, controlled trial investigating doxycycline, a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde4a7f1352470ce765cbbda6b8babfe
https://europepmc.org/articles/PMC8321570/
https://europepmc.org/articles/PMC8321570/
Autor:
Yijun Lin, Hwee Lin Wee, Cynthia Be Chee, Vanessa W. Lim, Vernon J. Lee, Timothy Barkham, Mei Xuan Tan, Peiling Yap, Lydia Wenxin Lin, Rick Twee-Hee Ong, Yi Roe Tan, Phoebe Lee, Mark I-Cheng Chen
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
BMJ Open
BMJ Open
ObjectivesWHO recommends that low burden countries consider systematic screening and treatment of latent tuberculosis infection (LTBI) in migrants from high incidence countries. We aimed to determine LTBI prevalence and risk factors and evaluate cost
Autor:
Michelle Li Wei Kam, Leo K.Y. Lim, Li-Hwei Sng, Rick Twee-Hee Ong, Vernon J.M. Lee, Yee Tang Wang, Cynthia B.E. Chee
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 134
To describe the molecular epidemiology of Mycobacterium tuberculosis complex (MTBC) and factors associated with its transmission in Singapore.Spoligotyping, 24-loci mycobacterial interspersed repetitive units - variable number of tandem repeats (MIRU
Autor:
John J. Totman, Tow Keang Lim, Yee Tang Wang, Nicholas I. Paton, David W. Townsend, James Thomas Patrick Decourcy Hallinan, Lih Kin Khor, Yan Pang, James S. Molton, Claire M. Naftalin, Benjamin A. Thomas, Cynthia B.E. Chee
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-7 (2019)
BMC Infectious Diseases
BMC Infectious Diseases
Background The understanding of early events following TB exposure is limited by traditional tests that rely on detection of an immune response to infection, which is delayed, or on imaging tests with low sensitivity for early disease. We investigate
Publikováno v:
Emerging Infectious Diseases, Vol 17, Iss 3, Pp 517-519 (2011)
We determined the proportion of foreign-born persons with tuberculosis (TB) in Singapore. This proportion increased from 25.5% in 2004 to 37.6% in 2009. Unskilled workers from countries with high incidences of TB accounted for the highest number of a
Externí odkaz:
https://doaj.org/article/2225d33a25bf4840b412a4ec9fbac0d4
Autor:
Yee Tang Wang, Suay Hong Gan, Cynthia B.E. Chee, Li Hwei Sng, Kyi Win KhinMar, Leo Kang Yang Lim, Li Wei Ang
Publikováno v:
Open Forum Infectious Diseases
Background Previously treated (ie, recurrent) tuberculosis (TB) cases account for approximately 7%–8% of incident TB globally and in Singapore. Molecular fingerprinting has enabled the differentiation of these patients into relapsed or reinfection