Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Cynthia B. Robinson"'
Publikováno v:
Clinical Reviews in Allergy & Immunology. 27:207-218
Advances in our understanding of asthma pathogenesis and delineation of the human genome project are yielding novel candidate targets for therapeutic intervention. In parallel with target identification, the past decade has produced novel approaches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b806968db65b57d48406ca035e78c3
https://doi.org/10.1385/criai:27:3:207
https://doi.org/10.1385/criai:27:3:207
Autor:
Cynthia B. Robinson
Publikováno v:
Clinics in Chest Medicine. 19:527-534
Cystic fibrosis (CF) remains an attractive target for cure by gene therapy. Results from several trials are reviewed in this article and have shown that mature airway epithelial cells are relatively resistant to gene transfer, that host immune respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66fcc35bd7f494ad7707389055516610
https://doi.org/10.1016/s0272-5231(05)70098-8
https://doi.org/10.1016/s0272-5231(05)70098-8
Publikováno v:
Pharmacologytherapeutics. 135(2)
Although reversible airway obstruction in part defines asthma, lung function as measured by spirometry alone inadequately predicts the value of new therapeutic agents in the treatment of severe asthma. Our objectives are 1) to review whether pulmonar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ce4774625439eb3819b5799450aa6f
https://pubmed.ncbi.nlm.nih.gov/22627271
https://pubmed.ncbi.nlm.nih.gov/22627271
Publikováno v:
Allergy and asthma proceedings. 31(6)
Inhaled dehydroepiandrosterone-3-sulfate (DHEAS), but not dehydroepiandrosterone (DHEA), possesses anti-inflammatory activity in in vitro assays and in models of allergen and lipopolysaccharide challenges. We postulated whether an inhaled suspension
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c40a6a3cba5cb66330b0d961138f2ac
https://pubmed.ncbi.nlm.nih.gov/21708057
https://pubmed.ncbi.nlm.nih.gov/21708057
Autor:
Reen Wu, Cynthia B. Robinson
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 29:469-477
We previously demonstrated that human tracheobronchial epithelial (TBE) cells synthesize mucin and form mucous granules in culture when they are maintained on a collagen gel (CG) substratum, but not on a plastic tissue culture surface or a thin colla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739dd3a6ca11b6177b22ab7db5ba227c
https://doi.org/10.1007/bf02639381
https://doi.org/10.1007/bf02639381
Autor:
Cynthia B. Robinson, Reen Wu
Publikováno v:
Journal of Tissue Culture Methods. 13:95-102
Reproducible techniques for the isolation and culture of conducting airway epithelial cells from various species including human are described. Tissues recovered after necropsy or surgery are treated with 0.1% protease at 4°C overnight. The epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31c9ea5d7500baec8d47410a62cc2e14
https://doi.org/10.1007/bf01666138
https://doi.org/10.1007/bf01666138
Autor:
Elsbeth C. Brown-Parr, Kathleen J. Propert, Mitchell J. Goldman, Colleen Baker, Cynthia B. Robinson, James M. Wilson, Karen McCoy, Jonathan B. Zuckerman, Joseph V. Hughes, Richard Shell, Narendra Chirmule, Thomas J. Sferra, Susan Magosin, John Tazelaar
Publikováno v:
Human gene therapy. 10(18)
A third-generation adenoviral vector containing recombinant human cystic fibrosis transmembrane conductance regulator (CFTR) gene was delivered by bronchoscope in escalating doses to the conducting airway of 11 volunteers with cystic fibrosis. Assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2307e7f6e4ec5d13e8b5dcd6ea2e6ee
https://pubmed.ncbi.nlm.nih.gov/10609658
https://pubmed.ncbi.nlm.nih.gov/10609658
Autor:
Paul V. Holland, Carroll E. Cross, Reen Wu, Cynthia B. Robinson, John L. Ratliff, Walter R. Martin
Publikováno v:
The American review of respiratory disease. 148(2)
Previous studies using the CA 19-9 antibody have demonstrated that serum mucin levels in patients with cystic fibrosis (CF) are elevated and that the degree of elevation relates to the age of the patient and possibly to his or her clinical status. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5273340478d487653c1a8d220ea93b9
https://pubmed.ncbi.nlm.nih.gov/8342902
https://pubmed.ncbi.nlm.nih.gov/8342902
Autor:
Reen Wu, Walter R. Martin, Cynthia B. Robinson, Judith A. St. George, Charles G. Plopper, Geoffrey Kurland, Jerold A. Last, Carroll E. Cross, Ruth J. McDonald, Richard Boucher
Publikováno v:
American journal of respiratory cell and molecular biology. 3(5)
The effects of culture conditions on growth and differentiation of human tracheobronchial epithelial (HTBE) cells have been defined. Epithelial cells were dissociated from tissues by protease treatment and were plated on tissue culture dishes in F12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfee7123b230b922f10d3aa801e760c
https://pubmed.ncbi.nlm.nih.gov/2223101
https://pubmed.ncbi.nlm.nih.gov/2223101
Autor:
Cynthia B. Robinson, Gibbe H. Parsons
Publikováno v:
Clinical Reviews in Allergy. 8
Inhalation challenge of pharmacologic agents to categorize the degree of bronchial hyperresponsiveness is a. powerful tool when appropriate standardization and data interpretation are duly considered. Investigations of both methodology and clinical u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c379e2f4f70493c4edccd41f26ebb8
https://doi.org/10.1007/bf02914441
https://doi.org/10.1007/bf02914441