Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cynthia A. Tse"'
Publikováno v:
The journal of spinal cord medicine. 41(3)
CONTEXT: Impaired balance function after a spinal cord injury (SCI) hinders performance of daily activities. OBJECTIVE: To assess the evidence on the effectiveness of task-specific training on sitting and standing function in individuals with SCI acr
Publikováno v:
Spinal cord. 55(10)
Cross-sectional study.To investigate the attentional requirements for maintaining standing balance in people with spinal cord injury (SCI) using a dual-task paradigm and to compare standing balance performance between SCI and able-bodied (AB) control
Publikováno v:
FEBS Journal. 273:3779-3791
Amylin-mediated islet beta-cell death is implicated in diabetogenesis. We previously reported that fibrillogenic human amylin (hA) evokes beta-cell apoptosis through linked activation of Jun N-terminal kinase 1 (JNK 1) and a caspase cascade. Here we
Publikováno v:
Diabetes. 50:1821-1827
We have recently identified a small phosphoprotein, P20, as a common intracellular target for insulin and several of its antagonists, including amylin, epinephrine, and calcitonin gene-related peptide. These hormones elicit phosphorylation of P20 at
Autor:
Garth J. S. Cooper, Cynthia A. Tse
Publikováno v:
Drugs & Aging. 9:202-212
Amylin, a 37-amino acid peptide, is cosecreted with insulin from the beta-cells of the pancreatic islets in normal response to physiological stimuli. It is the major protein of islet amyloid, which is usually present in the pancreases of people with
Publikováno v:
Cell Biology International. 17:317-324
The possibility that a growth-related proteinase may act by degrading a negative growth regulatory protein has been investigated. Proteinase inhibitors which inhibit the enzyme also enhance the accumulation of the growth regulator by human fibroblast
Autor:
Cynthia A. Tse, G. K. Scott
Publikováno v:
Biological Chemistry Hoppe-Seyler. 373:605-610
The proliferation of normal cells, and of early-passage cells from tumours, is inhibited as a consequence of inhibition of a cell-surface proteinase activity. In contrast, established tumour cell lines are usually resistant to these effects. It has p
Autor:
Michael C. Lam, Kathryn C.B. Tan, Cynthia A. Tse, Aimin Xu, Yu Wang, Karen S.L. Lam, Baoying Chen, Garth J. S. Cooper, Jialiang Zhang, Kok Weng Chan, Ruby L. C. Hoo
Publikováno v:
The Journal of biological chemistry. 280(18)
The antidiabetic hormone adiponectin circulates in blood as several oligomeric complexes, and the ratios between them are critical in determining insulin sensitivity. In this study we investigated the role of testosterone in regulating the oligomeric
Publikováno v:
Proteomics. 4(6)
Adipogenesis is an important aspect of energy homeostasis. Here we have used a differential proteome mapping strategy to identify intracellular proteins that are differentially expressed during adipose conversion of 3T3 L1 preadipocytes. Two-dimensio
Publikováno v:
Biochimica et biophysica acta. 1221(2)
Several reports have indicated that proteinase inhibitors can act as both stimulators and inhibitors of the growth of cultured cells. To confirm and extend these reports, we have purified the trypsin inhibitor from human urine (UTI). We have demonstr