Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Cynthia A. Morgan"'
Autor:
Ilana Chefetz, Edward Grimley, Kun Yang, Linda Hong, Ekaterina V. Vinogradova, Radu Suciu, Ilya Kovalenko, David Karnak, Cynthia A. Morgan, Mikhail Chtcherbinine, Cameron Buchman, Brandt Huddle, Scott Barraza, Meredith Morgan, Kara A. Bernstein, Euisik Yoon, David B. Lombard, Andrea Bild, Geeta Mehta, Iris Romero, Chun-Yi Chiang, Charles Landen, Benjamin Cravatt, Thomas D. Hurley, Scott D. Larsen, Ronald J. Buckanovich
Publikováno v:
Cell Reports, Vol 26, Iss 11, Pp 3061-3075.e6 (2019)
Summary: Ovarian cancer is typified by the development of chemotherapy resistance. Chemotherapy resistance is associated with high aldehyde dehydrogenase (ALDH) enzymatic activity, increased cancer “stemness,” and expression of the stem cell mark
Externí odkaz:
https://doaj.org/article/21d10f5934934f7c8c9e8ddf07b5d168
Autor:
David S. Watt, Thomas D. Hurley, Mykhaylo S. Frasinyuk, Peter J. Roach, Dyann M. Segvich, Krishna K. Mahalingan, Vimbai M. Chikwana, Cynthia A. Morgan, S. P. Bondarenko, Przemyslaw Wyrebek, Galyna P. Mrug, Anna A. DePaoli-Roach, Buyun Tang
Publikováno v:
J Med Chem
The over-accumulation of glycogen appears as a hallmark in various glycogen storage diseases (GSDs), including Pompe, Cori, Andersen and Lafora disease. Accumulating evidence suggests that suppression of glycogen accumulation represents a potential t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c645e897709680fc8bf4c7f1d4e3ca6
https://doi.org/10.1021/acs.jmedchem.9b01851
https://doi.org/10.1021/acs.jmedchem.9b01851
Autor:
Scott J. Barraza, Radu M. Suciu, Thomas D. Hurley, Mikhail Chtcherbinine, David Karnak, Euisik Yoon, Kara A. Bernstein, Ilya Kovalenko, Chun-Yi Chiang, Geeta Mehta, Ekaterina V. Vinogradova, Benjamin F. Cravatt, Brandt C. Huddle, Andrea H. Bild, Ronald J. Buckanovich, Iris L. Romero, Ilana Chefetz, Cynthia A. Morgan, Linda Hong, David B. Lombard, Edward Grimley, Scott D. Larsen, Charles N. Landen, Cameron D. Buchman, Meredith A. Morgan, Kun Yang
Publikováno v:
Cell Reports, Vol 26, Iss 11, Pp 3061-3075.e6 (2019)
Summary: Ovarian cancer is typified by the development of chemotherapy resistance. Chemotherapy resistance is associated with high aldehyde dehydrogenase (ALDH) enzymatic activity, increased cancer “stemness,” and expression of the stem cell mark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2cac15fa345ecc463e87abb08cc8ba
http://www.sciencedirect.com/science/article/pii/S2211124719302037
http://www.sciencedirect.com/science/article/pii/S2211124719302037
Autor:
Cameron D. Buchman, Siwei Li, Jeremy Felton, Geeta Mehta, Bikash Debnath, Edward Grimley, Scott D. Larsen, Brandt C. Huddle, Ronald J. Buckanovich, Duxin Sun, Pooja Mehta, Mikhail Chtcherbinine, Thomas D. Hurley, Kun Yang, Cynthia A. Morgan, Nouri Neamati
Publikováno v:
Journal of medicinal chemistry. 61(19)
Aldehyde dehydrogenase (ALDH) activity is commonly used as a marker to identify cancer stem-like cells. The three ALDH1A isoforms have all been individually implicated in cancer stem-like cells and in chemoresistance; however, which isoform is prefer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035234b9aea738665d2f4f1229c340fd
https://pubmed.ncbi.nlm.nih.gov/30221940
https://pubmed.ncbi.nlm.nih.gov/30221940
Autor:
Thomas D. Hurley, Cynthia A. Morgan
Publikováno v:
Chemico-Biological Interactions. 234:29-37
The human aldehyde dehydrogenase (ALDH) superfamily consists of at least 19 enzymes that metabolize endogenous and exogenous aldehydes. Currently, there are no commercially available inhibitors that target ALDH1A1 but have little to no effect on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931a7914da6477ebf6c9e48ae4baac64
https://doi.org/10.1016/j.cbi.2014.10.028
https://doi.org/10.1016/j.cbi.2014.10.028
Autor:
Cynthia A. Morgan
Nel mistico regno di Jyndari, una relazione fiorisce tra due anime ignare ma affini. Ayla, una Guardiana di bambini fatati e Fata della Luce, nasconde non pochi segreti, segreti che la isolano e la separano dal resto del popolo. Ma le velate confiden
Autor:
Cynthia A. Morgan
No reino místico de Jyndari, surge um relacionamento entre duas desavisadas almas gêmeas. Ayla, uma Guardiã de Crianças que ama a Luz, esconde diversos segredos, que a isolam e separam do resto de seu povo. No entanto, as habilidades ocultas da f
Autor:
Leigh A Minchew, Cynthia L Morgan
Publikováno v:
The Journal of nursing education. 55(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655ace0d793174fbcbdc1549d340d938
https://pubmed.ncbi.nlm.nih.gov/27783823
https://pubmed.ncbi.nlm.nih.gov/27783823
Autor:
Jean E. Lachowicz, Geoffrey B. Varty, Robert J. Naylor, Guy A. Higgins, Eric M. Parker, Cynthia A. Morgan, Ruth A. Duffy
Publikováno v:
Pharmacology Biochemistry and Behavior. 102:95-100
NK1 receptor antagonists have been shown to have a variety of physiological and potential therapeutic effects in animal models and in humans. The present studies demonstrate that Rolapitant (SCH 619734, (5S)-8(S)-[[1(R)-[3,5 bis(trifluoromethyl)pheny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28e3b293969e6ef53f92a6d13634048
https://doi.org/10.1016/j.pbb.2012.03.021
https://doi.org/10.1016/j.pbb.2012.03.021
Autor:
Cynthia R. Morgan, Renee A. McPherson, Alexandria G. McCombs, Christopher A. Fiebrich, Peter K. Hall
Publikováno v:
Journal of Atmospheric and Oceanic Technology. 27:1565-1582
Mesoscale meteorological data present their own challenges and advantages during the quality assurance (QA) process because of their variability in both space and time. To ensure data quality, it is important to perform quality control at many differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f247b78b4dcb272dbcc2365f607018a
https://doi.org/10.1175/2010jtecha1433.1
https://doi.org/10.1175/2010jtecha1433.1