Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Cynthia A. Carnes"'
Autor:
Mark A. Munger, Yusuf Olğar, Megan L. Koleske, Heather L. Struckman, Jessica Mandrioli, Qing Lou, Ingrid Bonila, Kibum Kim, Roberto Ramos Mondragon, Silvia G. Priori, Pompeo Volpe, Héctor H. Valdivia, Joseph Biskupiak, Cynthia A. Carnes, Rengasayee Veeraraghavan, Sándor Györke, Przemysław B. Radwański
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 11 (2020)
Background Atrial fibrillation (AF) is a comorbidity associated with heart failure and catecholaminergic polymorphic ventricular tachycardia. Despite the Ca2+‐dependent nature of both of these pathologies, AF often responds to Na+ channel blockers.
Externí odkaz:
https://doaj.org/article/c3b12da609534a84822dec8d477ebd3b
Autor:
Vineeta Tanwar, Matthew W. Gorr, Markus Velten, Clayton M. Eichenseer, Victor P. Long, Ingrid M. Bonilla, Vikram Shettigar, Mark T. Ziolo, Jonathan P. Davis, Stephen H. Baine, Cynthia A. Carnes, Loren E. Wold
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 4 (2017)
BackgroundParticulate matter (PM; PM2.5 [PM with diameters of
Externí odkaz:
https://doaj.org/article/8834cc780b87467b95f629cf680a40a2
Autor:
Amy C. Sturm, Crystal F. Kline, Patric Glynn, Benjamin L. Johnson, Jerry Curran, Ahmet Kilic, Robert S. D. Higgins, Philip F. Binkley, Paul M. L. Janssen, Raul Weiss, Subha V. Raman, Steven J. Fowler, Silvia G. Priori, Thomas J. Hund, Cynthia A. Carnes, Peter J. Mohler
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 4, Iss 5, Pp n/a-n/a (2015)
Background Identified genetic variants are insufficient to explain all cases of inherited arrhythmia. We tested whether the integration of whole exome sequencing with well‐established clinical, translational, and basic science platforms could provi
Externí odkaz:
https://doaj.org/article/e4f120ba886c443b8dc73f4dcedbceac
Autor:
Ingrid M. Bonilla, Stephen Baine, Anastasia Pokrass, Juan Ignacio Elio Mariángelo, Anuradha Kalyanasundaram, Vladimir Bogdanov, Louisa Mezache, Galina Sakuta, Casey M. Beard, Andriy Belevych, Svetlana Tikunova, Radmila Terentyeva, Dmitry Terentyev, Jonathan Davis, Rengasayee Veeraraghavan, Cynthia A. Carnes, Sandor Györke
Publikováno v:
Journal of Applied Physiology. 134:1287-1299
Store-operated Ca2+ entry (SOCE) has been implicated in pathological cardiac hypertrophy; however, its role in physiological hypertrophy is unknown. Here we report that SOCE is also essential for physiological cardiac hypertrophy and functional adapt
Autor:
Charlotte M. Forshay, John Mellett, Marcia M. Worley, Cynthia A. Carnes, Andre Fernandes, Trisha A. Jordan
Publikováno v:
Hospital Pharmacy. 58:188-193
Purpose: Medications that require prior authorization can complicate the discharge planning process. This study implemented and evaluated a process for identifying and completing prior authorizations during the inpatient setting prior to patient disc
Autor:
Muhammad Erfan Uddin, Eric D. Eisenmann, Yang Li, Kevin M. Huang, Dominique A. Garrison, Zahra Talebi, Alice A. Gibson, Yan Jin, Mahesh Nepal, Ingrid M. Bonilla, Qiang Fu, Xinxin Sun, Alec Millar, Mikhail Tarasov, Christopher E. Jay, Xiaoming Cui, Heidi J. Einolf, Ryan M. Pelis, Sakima A. Smith, Przemysław B. Radwański, Douglas H. Sweet, Jörg König, Martin F. Fromm, Cynthia A. Carnes, Shuiying Hu, Alex Sparreboom
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8607
Dofetilide is a rapid delayed rectifier potassium current inhibitor widely used to prevent the recurrence of atrial fibrillation and flutter. The clinical use of this drug is associated with increases in QTc interval, which predispose patients to ven
Autor:
Andriy E. Belevych, Stephen Baine, Andrei V. Stepanov, Sandor Gyorke, Lisa E. Dorn, Ingrid M. Bonilla, Cynthia A. Carnes, Radmila Terentyeva, Dmitry Terentyev, Federica Accornero
Publikováno v:
Journal of Cellular and Molecular Medicine
Heart failure (HF) is characterized by asymmetrical autonomic balance. Treatments to restore parasympathetic activity in human heart failure trials have shown beneficial effects. However, mechanisms of parasympathetic‐mediated improvement in cardia
Publikováno v:
Journal of Clinical and Translational Science, Vol 3, Pp 75-75 (2019)
OBJECTIVES/SPECIFIC AIMS: Verbal communication is a critical component for professional development and leadership. Yet, many clinical translational scientists lack the skills in communication of their scientific work in a meaningful and exciting man
Externí odkaz:
https://doaj.org/article/3552579e291f4276a0819eaae06d7cbf
Autor:
Sandor Gyorke, Stephen Baine, Rengasayee Veeraraghavan, Ingrid M. Bonilla, Przemysław B. Radwański, Marina S. Ivanova, Justin Thomas, Cynthia A. Carnes, Jiaoni Li, Andriy E. Belevych
Publikováno v:
J Biol Chem
Post-translational modifications of proteins involved in calcium handling in myocytes, such as the cardiac ryanodine receptor (RyR2), critically regulate cardiac contractility. Recent studies have suggested that phosphorylation of RyR2 by protein kin
Autor:
Shanna Hamilton, Radmila Terentyeva, Vladimir Bogdanov, Tae Yun Kim, Fruzsina Perger, Jiajie Yan, Xun Ai, Cynthia A. Carnes, Andriy E. Belevych, Christopher H. George, Jonathan P. Davis, Sandor Gyorke, Bum-Rak Choi, Dmitry Terentyev
Publikováno v:
Circ Res
Background: Oxidative stress in cardiac disease promotes proarrhythmic disturbances in Ca 2+ homeostasis, impairing luminal Ca 2+ regulation of the sarcoplasmic reticulum (SR) Ca 2+ release channel, the RyR2 (ryanodine receptor), and increasing chann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b7202f4cbc512ceb056b6b1653a578
https://cronfa.swan.ac.uk/Record/cronfa59209/Download/59209__23761__d3f53bf864294e008bf6fb9cc8bccb75.pdf
https://cronfa.swan.ac.uk/Record/cronfa59209/Download/59209__23761__d3f53bf864294e008bf6fb9cc8bccb75.pdf