Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases.

Autor: Hélène Arnould, Vincent Baudouin, Anne Baudry, Luiz W Ribeiro, Hector Ardila-Osorio, Mathéa Pietri, Cédric Caradeuc, Cynthia Soultawi, Declan Williams, Marjorie Alvarez, Carole Crozet, Fatima Djouadi, Mireille Laforge, Gildas Bertho, Odile Kellermann, Jean-Marie Launay, Gerold Schmitt-Ulms, Benoit Schneider

Publikováno v: PLoS Pathogens, Vol 17, Iss 10, p e1009991 (2021)

Corruption of cellular prion protein (PrPC) function(s) at the plasma membrane of neurons is at the root of prion diseases, such as Creutzfeldt-Jakob disease and its variant in humans, and Bovine Spongiform Encephalopathies, better known as mad cow d

Externí odkaz: https://doaj.org/article/e0f84de0ab084344b839c7190a6a9010

Mitochondrial Bioenergetics and Dynamics During Infection

Autor: Mireille Laforge, Yasmina Fortier, Calaiselvy Soundaramourty, Cynthia Soultawi, Jérôme Estaquier

Publikováno v: Metabolic Interaction in Infection
Metabolic Interaction in Infection, pp.221-233, 2018, ⟨10.1007/978-3-319-74932-7_5⟩
Experientia Supplementum ISBN: 9783319749310

Microbes have developed a series of strategies to overcome the defense mechanisms of the infected host. During pathogen–host coevolution, they develop strategy to manipulate cellular machinery particularly in subverting mitochondrion function. Mito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92d05e57cad0882b65e7241db64dceb
https://hal.archives-ouvertes.fr/hal-03089840