Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Cynthia, Shannon Weickert"'
Autor:
Hayley F. North, Christin Weissleder, Maina Bitar, Guy Barry, Janice M. Fullerton, Maree J. Webster, Cynthia Shannon Weickert
Publikováno v:
Schizophrenia, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract A subgroup of schizophrenia cases with elevated inflammation have reduced neurogenesis markers and increased macrophage density in the human subependymal zone (SEZ; also termed subventricular zone or SVZ) neurogenic niche. Inflammation can i
Externí odkaz:
https://doaj.org/article/43094bb7cd794a43b5423900229c3897
Autor:
Kankana Nisha Aji, Sina Hafizi, Tania Da Silva, Michael Kiang, Pablo M. Rusjan, Cynthia Shannon Weickert, Romina Mizrahi
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 30, Iss , Pp 100636- (2023)
Neuroinflammatory events prior to the diagnosis of schizophrenia may play a role in transition to illness. To date only one in-vivo study has investigated this association between peripheral proinflammatory cytokines and brain markers of inflammation
Externí odkaz:
https://doaj.org/article/a56e0dc9ca4b4c229502e72ad0287e10
Autor:
Mainá Bitar, Christin Weissleder, Hayley F. North, Misaki S. Clearwater, Oressia Zalucki, Glenda M. Halliday, Maree J. Webster, Michael Piper, Cynthia Shannon Weickert, Guy Barry
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The generation of new neurons within the mammalian forebrain continues throughout life within two main neurogenic niches, the subgranular zone (SGZ) of the hippocampal dentate gyrus, and the subependymal zone (SEZ) lining the lateral ventric
Externí odkaz:
https://doaj.org/article/9fb28e833e2a4b5da74e8d0075ffd3b1
Autor:
Caitlin E. Murphy, Adam K. Walker, Maryanne O’Donnell, Cherrie Galletly, Andrew R. Lloyd, Dennis Liu, Cynthia Shannon Weickert, Thomas W. Weickert
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Elevations in plasma levels of pro-inflammatory cytokines and C-reactive protein (CRP) in patient blood have been associated with impairments in cognitive abilities and more severe psychiatric symptoms in people with schizophrenia. The trans
Externí odkaz:
https://doaj.org/article/5ff14a64c66b433aaac7f8ed1485a447
Autor:
Hayley F. North, Christin Weissleder, Janice M. Fullerton, Rachel Sager, Maree J. Webster, Cynthia Shannon Weickert
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Inflammation regulates neurogenesis, and the brains of patients with schizophrenia and bipolar disorder have reduced expression of neurogenesis markers in the subependymal zone (SEZ), the birthplace of inhibitory interneurons. Inflammation i
Externí odkaz:
https://doaj.org/article/0e77c55fa83748ecb0f9b24fd854d58e
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Neuroinflammation, particularly in the dorsolateral prefrontal cortex, is well-established in a subset of people with schizophrenia, with significant increases in inflammatory markers including several cytokines. Yet the cause(s) of cortical
Externí odkaz:
https://doaj.org/article/d366e4e8133f4b379cd08e45994f333c
Autor:
Gabriela Visini, Samara Brown, Katrina Weston-Green, Cynthia Shannon Weickert, Rose Chesworth, Tim Karl
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Cannabidiol (CBD) is a non-intoxicating cannabinoid with antipsychotic-like properties, however it’s potential to prevent schizophrenia development has not been thoroughly investigated. Brain maturation during adolescence creates a window where CBD
Externí odkaz:
https://doaj.org/article/87fb3c7cf03d4b9f9d28c189a49ccb26
Autor:
Tertia D. Purves-Tyson, Amelia M. Brown, Christin Weissleder, Debora A. Rothmond, Cynthia Shannon Weickert
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-19 (2021)
Abstract Reductions in the GABAergic neurotransmitter system exist across multiple brain regions in schizophrenia and encompass both pre- and postsynaptic components. While reduced midbrain GABAergic inhibitory neurotransmission may contribute to the
Externí odkaz:
https://doaj.org/article/fc6b3499f9d048d3b8fbc72a998340f8
Autor:
Caitlin E. Murphy, Adam J. Lawther, Maree J. Webster, Makoto Asai, Yuji Kondo, Mitsuyuki Matsumoto, Adam K. Walker, Cynthia Shannon Weickert
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background High inflammation status despite an absence of known infection characterizes a subpopulation of people with schizophrenia who suffer from more severe cognitive deficits, less cortical grey matter, and worse neuropathology. Transcr
Externí odkaz:
https://doaj.org/article/a52e9042bca44634a81bf925e794e9d1
Autor:
Benjamin C. Reiner, Glenn A. Doyle, Andrew E. Weller, Rachel N. Levinson, Esin Namoglu, Alicia Pigeon, Emilie Dávila Perea, Cynthia Shannon Weickert, Gustavo Turecki, Deborah C. Mash, Richard C. Crist, Wade H. Berrettini
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 5, Pp 1647-1655 (2020)
Long interspersed element-1 retrotransposons (LINE-1 or L1) are ∼6 kb mobile DNA elements implicated in the origins of many Mendelian and complex diseases. The actively retrotransposing L1s are mostly limited to the L1 human specific (L1Hs) transcr
Externí odkaz:
https://doaj.org/article/b4f24c25c33048b8ad162a2ff355cb5b