Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Cyndia Charfi"'
Autor:
Michel Demeule, Jean-Christophe Currie, Cyndia Charfi, Alain Zgheib, Isabelle Cousineau, Véronique Lullier, Richard Béliveau, Christian Marsolais, Borhane Annabi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/6650e39567554634907d3b719c025f52
Autor:
Michel Demeule, Jean-Christophe Currie, Cyndia Charfi, Alain Zgheib, Isabelle Cousineau, Véronique Lullier, Richard Béliveau, Christian Marsolais, Borhane Annabi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The anticancer efficacy of Sudocetaxel Zendusortide (TH1902), a peptide-drug conjugate internalized through a sortilin-mediated process, was assessed in a triple-negative breast cancer-derived MDA-MB-231 immunocompromised xenograft tumor model where
Externí odkaz:
https://doaj.org/article/406adb6e515441f688e79a799ed206ee
Autor:
Cyndia Charfi, Michel Demeule, Jean-Christophe Currie, Alain Larocque, Alain Zgheib, Bogdan Alexandru Danalache, Amira Ouanouki, Richard Béliveau, Christian Marsolais, Borhane Annabi
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Vasculogenic mimicry (VM) is defined as the formation of microvascular channels by genetically deregulated cancer cells and is often associated with high tumor grade and cancer therapy resistance. This microcirculation system, independent of endothel
Externí odkaz:
https://doaj.org/article/9856283e5a394452a64411b0a22a4d2f
Autor:
Michel Demeule, Cyndia Charfi, Jean-Christophe Currie, Alain Zgheib, Bogdan Alexandru Danalache, Richard Béliveau, Christian Marsolais, Borhane Annabi
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1910 (2022)
Background: Breast and ovarian cancer stem cells (CSC) can contribute to the invasive and chemoresistance phenotype of tumors. TH1902, a newly developed sortilin (SORT1)-targeted peptide-docetaxel conjugate is currently in phase-1 clinical trial. Whe
Externí odkaz:
https://doaj.org/article/0b8a08e7364d4c5baf46b5c7fe2801e9
Autor:
Cyndia Charfi, Michel Demeule, Jean-Christophe Currie, Alain Zgheib, Bogdan Alexandru Danalache, Richard Béliveau, Christian Marsolais, Borhane Annabi
Publikováno v:
Cancer Research. 83:4493-4493
Over the last decade, the targeting of specific cell surface receptors such as human epidermal growth factor receptor 2 (Her2) in breast cancer cells has allowed the emergence of innovative strategies for the delivery of anticancer agents. High expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a24ce882dd8efb53825e5d1914172b07
https://doi.org/10.1158/1538-7445.am2023-4493
https://doi.org/10.1158/1538-7445.am2023-4493
Autor:
Michel Demeule, Jean-Christophe Currie, Cyndia Charfi, Alain Zgheib, Isabelle Cousineau, Richard Béliveau, Christian Marsolais, Borhane Annabi
Publikováno v:
Cancer Research. 83:4499-4499
Tumor-infiltrating immune cells are involved in the control of cancer and are closely related to clinical outcomes. Sudocetaxel Zendusortide (TH1902), a peptide-drug conjugate (PDC) of the sortilin (SORT1)-binding peptide TH19P01 ester-linked to two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cdaa33b4400848c4fa428fec9c7d21d
https://doi.org/10.1158/1538-7445.am2023-4499
https://doi.org/10.1158/1538-7445.am2023-4499
Autor:
Borhane Annabi, Cyndia Charfi, Jean-Christophe Currie, Alain Zgheib, Alain Larocque, Richard Béliveau, Christian Marsolais, Michel Demeule
Publikováno v:
Cancer Research. 80:P3-10
Background: Triple-negative breast cancer (TNBC) still lacks defined molecular biomarkers. Thus, targeting of specific gene/protein molecular signature of tumors emerged among the best anticancer strategies. Recently, increased expression of the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c1f4731218349aba7e7a889967cbd2a
https://doi.org/10.1158/1538-7445.sabcs19-p3-10-07
https://doi.org/10.1158/1538-7445.sabcs19-p3-10-07
Autor:
Jean-Christophe Currie, Michel Demeule, Cyndia Charfi, Alain Zgheib, Alain Larocque, Bogdan Alexandru Danalache, Amira Ouanouki, Richard Béliveau, Christian Marsolais, Borhane Annabi
Publikováno v:
Cancers; Volume 14; Issue 8; Pages: 1877
Sortilin (SORT1) receptor-mediated endocytosis functions were exploited for this new approach for effective and safe treatments of gynecological cancers. Here, high expression of SORT1 was found in >75% of the clinically annotated ovarian and endomet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292385f8601ef91425611e3e53d2bcde
https://pubmed.ncbi.nlm.nih.gov/35454785
https://pubmed.ncbi.nlm.nih.gov/35454785
Autor:
Amira Ouanouki, Cyndia Charfi, Christian Marsolais, Alain Zgheib, Richard Béliveau, Bogdan Alexandru Danalache, Alain Larocque, Borhane Annabi, Jean-Christophe Currie, Michel Demeule
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
Vasculogenic mimicry (VM) is defined as the formation of microvascular channels by genetically deregulated cancer cells and is often associated with high tumor grade and cancer therapy resistance. This microcirculation system, independent of endothel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4ce38dc84e6bdeae21d84e1f99604b
https://www.frontiersin.org/articles/10.3389/fonc.2021.760787/full
https://www.frontiersin.org/articles/10.3389/fonc.2021.760787/full
Autor:
Borhane Annabi, Sophie Kozelko, Jean-Christophe Currie, Alain Larocque, Richard Béliveau, Michel Demeule, Cyndia Charfi, Alain Zgheib, Christian Marsolais
Publikováno v:
Cancer Science
Triple‐negative breast cancer (TNBC) is a heterogeneous subgroup of cancers which lacks the expression and/or amplification of targetable biomarkers (ie, estrogen receptor, progestrogen receptor, and human epidermal growth factor receptor 2), and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d586895285e4d432b6a62fd47d5f0a
https://pubmed.ncbi.nlm.nih.gov/34314556
https://pubmed.ncbi.nlm.nih.gov/34314556