Zobrazeno 1 - 10
of 1 289
pro vyhledávání: '"Cyganek A"'
Autor:
Gideon Syed Ali, Sabine Rebs, Hanna Eberl, Clarissa Zinke, Daniela Hübscher, Wiebke Maurer, Alexandra Busley, Lukas Cyganek, Katrin Streckfuss-Bömeke
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103538- (2024)
Takotsubo Syndrome (TTS) is a potentially life-threatening disease characterized by a transient left ventricular apical akinesia in response to β-adrenergic overstimulation. Since a genetic predisposition is assumed, we generated an iPSC-line carryi
Externí odkaz:
https://doaj.org/article/2d087a29afb247c79218229540a460cb
Autor:
Jihyun Lee, Eliane Duperrex, Ibrahim El-Battrawy, Alyssa Hohn, Ardan M. Saguner, Firat Duru, Vishalini Emmenegger, Lukas Cyganek, Andreas Hierlemann, Hasan Ulusan
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
IntroductionIn recent years, high-density microelectrode arrays (HD-MEAs) have emerged as a valuable tool in preclinical research for characterizing the electrophysiology of human induced pluripotent stem-cell-derived cardiomyocytes (iPSC-CMs). HD-ME
Externí odkaz:
https://doaj.org/article/a027b4206ff64aacbc594cc330d8ac9b
Autor:
Alexandra Viktoria Busley, Óscar Gutiérrez-Gutiérrez, Elke Hammer, Fabian Koitka, Amin Mirzaiebadizi, Martin Steinegger, Constantin Pape, Linda Böhmer, Henning Schroeder, Mandy Kleinsorge, Melanie Engler, Ion Cristian Cirstea, Lothar Gremer, Dieter Willbold, Janine Altmüller, Felix Marbach, Gerd Hasenfuss, Wolfram-Hubertus Zimmermann, Mohammad Reza Ahmadian, Bernd Wollnik, Lukas Cyganek
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114448- (2024)
Summary: Noonan syndrome patients harboring causative variants in LZTR1 are particularly at risk to develop severe and early-onset hypertrophic cardiomyopathy. In this study, we investigate the mechanistic consequences of a homozygous variant LZTR1L5
Externí odkaz:
https://doaj.org/article/199d047ff2b846ddbbff360254a381ed
Autor:
Michał Koziarski, Bogusław Cyganek, Przemysław Niedziela, Bogusław Olborski, Zbigniew Antosz, Marcin Żydak, Bogdan Kwolek, Paweł Wąsowicz, Andrzej Bukała, Jakub Swadźba, Piotr Sitkowski
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Cancer diseases constitute one of the most significant societal challenges. In this paper, we introduce a novel histopathological dataset for prostate cancer detection. The proposed dataset, consisting of over 2.6 million tissue patches extr
Externí odkaz:
https://doaj.org/article/f23b38eb892e4544bb6a7917499a9e16
Autor:
Łażewski, Stanisław1 (AUTHOR) slazewsk@agh.edu.pl, Cyganek, Bogusław1 (AUTHOR)
Publikováno v:
Integrated Computer-Aided Engineering. 2024, Vol. 31 Issue 3, p267-284. 18p.
Autor:
Gąsienica-Józkowy, Jan1 (AUTHOR) j.gasienica@myled.pl, Cyganek, Bogusław1 (AUTHOR) cyganek@agh.edu.pl, Knapik, Mateusz1 (AUTHOR), Głogowski, Szymon2 (AUTHOR) s.glogowski@myled.pl, Przebinda, Łukasz2 (AUTHOR) l.przebinda@myled.pl
Publikováno v:
Information (2078-2489). Aug2024, Vol. 15 Issue 8, p474. 15p.
Autor:
Busley, Alexandra Viktoria, Gutiérrez-Gutiérrez, Óscar, Hammer, Elke, Koitka, Fabian, Mirzaiebadizi, Amin, Steinegger, Martin, Pape, Constantin, Böhmer, Linda, Schroeder, Henning, Kleinsorge, Mandy, Engler, Melanie, Cirstea, Ion Cristian, Gremer, Lothar, Willbold, Dieter, Altmüller, Janine, Marbach, Felix, Hasenfuss, Gerd, Zimmermann, Wolfram-Hubertus, Ahmadian, Mohammad Reza, Wollnik, Bernd, Cyganek, Lukas
Publikováno v:
In Cell Reports 23 July 2024 43(7)
Autor:
Jochen Dobner, Thach Nguyen, Mario Gustavo Pavez-Giani, Lukas Cyganek, Felix Distelmaier, Jean Krutmann, Alessandro Prigione, Andrea Rossi
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101231- (2024)
Mitochondrial DNA (mtDNA) analysis is crucial for the diagnosis of mitochondrial disorders, forensic investigations, and basic research. Existing pipelines are complex, expensive, and require specialized personnel. In many cases, including the diagno
Externí odkaz:
https://doaj.org/article/d31d09eb2eb54ccb8689a2489ed1f56a
Autor:
Dobner, Jochen, Nguyen, Thach, Pavez-Giani, Mario Gustavo, Cyganek, Lukas, Distelmaier, Felix, Krutmann, Jean, Prigione, Alessandro, Rossi, Andrea
Publikováno v:
In Molecular Therapy - Methods & Clinical Development 13 June 2024 32(2)
Autor:
Koziarski, Michał, Cyganek, Bogusław, Niedziela, Przemysław, Olborski, Bogusław, Antosz, Zbigniew, Żydak, Marcin, Kwolek, Bogdan, Wąsowicz, Paweł, Bukała, Andrzej, Swadźba, Jakub, Sitkowski, Piotr
Cancer diseases constitute one of the most significant societal challenges. In this paper, we introduce a novel histopathological dataset for prostate cancer detection. The proposed dataset, consisting of over 2.6 million tissue patches extracted fro
Externí odkaz:
http://arxiv.org/abs/2105.04014
