Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Cydney Nichols"'
Autor:
Yongsheng Ruan, Hye Na Kim, Heather A. Ogana, Zesheng Wan, Samantha Hurwitz, Cydney Nichols, Nour Abdel-Azim, Ariana Coba, Seyoung Seo, Yong-Hwee Eddie Loh, Eun Ji Gang, Hisham Abdel-Azim, Chih-Lin Hsieh, Michael R. Lieber, Chintan Parekh, Dhananjaya Pal, Deepa Bhojwani, Donald L. Durden, Yong-Mi Kim
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The PI3K/Akt pathway—and in particular PI3Kδ—is known for its role in drug resistant B-cell acute lymphoblastic leukemia (B-ALL) and it is often upregulated in refractory or relapsed B-ALL. Myc proteins are transcription factors responsible for
Externí odkaz:
https://doaj.org/article/9d2a16f695cc4722b8574521dd391e56
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 2, p 412 (2019)
Adhesion of acute lymphoblastic leukemia (ALL) cells to bone marrow stroma cells triggers intracellular signals regulating cell-adhesion-mediated drug resistance (CAM-DR). Stromal cell protection of ALL cells has been shown to require active AKT. In
Externí odkaz:
https://doaj.org/article/e1cc740693b2426493d0f336ee2b9712
Publikováno v:
Curr Top Microbiol Immunol
Current Topics in Microbiology and Immunology ISBN: 9783031065651
Current Topics in Microbiology and Immunology ISBN: 9783031065651
Despite the therapeutic progress, relapse remains a major problem in the treatment of acute lymphoblastic leukemia (ALL). Most leukemia cells that survive chemotherapy are found in the bone marrow (BM), thus resistance to chemotherapy and other treat
Publikováno v:
Venereology, Vol 2, Iss 4, Pp 173-179 (2023)
Sexually transmitted infections (STIs) constitute a major public health issue in the United States. North Carolina (NC) in the southeastern U.S. ranks among the highest in STI incidence. We aimed to describe the incidence rates and identify potential
Externí odkaz:
https://doaj.org/article/526aeacd2c1247e7b1c566d495d817ef
Autor:
Allyson Flower, Delong Liu, Rosemarie Shaw, Karen Seiter, Cydney Nichols, Mitchell S. Cairo, Yaya Chu, Carmella van de Ven, Jordan Milner, Janet Ayello, Sandra Fabricatore, Erin Morris
Publikováno v:
Blood. 136:32-33
Background: Graft versus host disease (GVHD) is a life-threatening complication following allogeneic stem cell transplantation (AlloSCT), which results from allo-reactive donor T-cells reacting against human leukocyte antigen (HLA) disparate host ant
Autor:
Cydney Nichols, Tiffany N. Seagroves, M. Angeles Lillo, Susan A. Krum, Gustavo A. Miranda-Carboni
Publikováno v:
Hormones and Cancer. 8:90-99
Bisphenol A (BPA) is an endocrine disrupting compound used in food and beverage plastic containers and has been shown to increase breast cancer cellular proliferation. However, the concentrations of BPA used in these experiments are far higher than t
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 2, p 412 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 2, p 412 (2019)
Adhesion of acute lymphoblastic leukemia (ALL) cells to bone marrow stroma cells triggers intracellular signals regulating cell-adhesion-mediated drug resistance (CAM-DR). Stromal cell protection of ALL cells has been shown to require active AKT. In
Autor:
Cydney Nichols, Chanel D. Perry, Stephanie Runke, M. Angeles Lillo, Susan A. Krum, Raisa I. Krutilina, Gustavo A. Miranda-Carboni, Tiffany N. Seagroves
Publikováno v:
Journal of Applied Toxicology. 37:417-425
A body of epidemiological evidence implicates exposure to endocrine disrupting chemicals (EDCs) with increased susceptibility to breast cancer. To evaluate the physiological effects of a suspected EDC in vivo, we exposed MCF-7 breast cancer cells and
Autor:
Hye Na Kim, Cydney Nichols, Donald L. Durden, Nour Abdel-Azim, Enzi Ji Jiang, Yong-Mi Kim, Ariana Coba
Publikováno v:
Blood. 132:1420-1420
Introduction: Acute lymphoblastic leukemia is the most prevalent form of cancer affecting children with 2,500-3,500 new cases per year. More effective targeted therapies have yielded a current five-year survival rate of at least 85% for children; how
Publikováno v:
Cancer Research. 74:3192-3192
A study by the Centers for Disease Control revealed detectable levels of the environmental toxin Bisphenol A (BPA) in urine samples from over 92% of people in the NHANES (National Health and Nutrition Examination Survey) study. BPA is a small molecul