Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Cyclosporine/*pharmacology"'
1
Effect of immunosuppressive drugs on cytokine production in canine whole blood stimulated with lipopolysaccharide or a combination of ionomycin and phorbol 12‐myristate 13‐acetate
Autor: Lakshmi Narayanan, Simon M. Firestone, Todd M. Archer, Caroline S Mansfield, Julien R.S. Dandrieux
Publikováno v: Dandrieux, J R S, Narayanan, L, Firestone, S, Archer, T M & Mansfield, C S 2019, ' Effect of immunosuppressive drugs on cytokine production in canine whole blood stimulated with lipopolysaccharide or a combination of ionomycin and phorbol 12-myristate 13-acetate ', Veterinary Medicine and Science, vol. 5, no. 2, pp. 199-205 . https://doi.org/10.1002/vms3.143
Veterinary Medicine and Science
A pharmacodynamic assay has been previously developed to monitor ciclosporin treatment in dogs by assessing inhibition of cytokine transcription after whole blood stimulation with 12‐myristate 13‐1 acetate and ionomycin (PMA/I). In this study, wh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05bee1d1ba6bdd4b8933ab4e8f82b9e
https://doi.org/10.1002/vms3.143
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2
Cyclosporine A impairs bone repair in critical defects filled with different osteoconductive bone substitutes
Autor: Rubens Spin-Neto, Andreas Stavropoulos, Guilherme José Pimentel Lopes de Oliveira, Cássio Rocha Scardueli, Fernanda Castanheira Gonçalves, Rosemary Adriana Chierici Marcantonio
Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Brazilian Oral Research, Vol 34 (2020)
Gonçalves, F C, Oliveira, G J P L D, Scardueli, C R, Spin-Neto, R, Stavropoulos, A & Marcantonio, R A C 2020, ' Cyclosporine A impairs bone repair in critical defects filled with different osteoconductive bone substitutes ', Brazilian Oral Research, vol. 34, e007 . https://doi.org/10.1590/1807-3107bor-2020.vol34.0007
Brazilian Oral Research, Volume: 34, Article number: e007, Published: 07 FEB 2020
Brazilian Oral Research v.34 2020
Brazilian Oral Research
Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
Made available in DSpace on 2020-12-12T01:56:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 The aim of this study was to assess the influence of cyclosporine administration on the repair of critical-sized calvaria defects (CSDs) in r
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3
Impact of daclizumab, low-dose cyclosporine, mycophenolate mofetil and steroids on renal function after kidney transplantation
Autor: Fangmann, Josef, Arns, Wolfgang, Marti, Hans-Peter, Hauss, Johann, Ketteler, Markus, Beckurts, Tobias, Boesmueller, Claudia, Pohanka, Erich, Martin, Pierre-Yves, Gerhardt, Moritz, Farese, Stefan, Neumayer, Hans-H, Floege, Juergen, Gurr, Caroline, Budde, Klemens, DACH Study Group
Publikováno v: Nephrology, Dialysis, Transplantation, Vol. 25, No 1 (2010) pp. 283-292
Fangmann, Josef; Arns, Wolfgang; Marti, Hans-Peter; Hauss, Johann; Ketteler, Markus; Beckurts, Tobias; Boesmueller, Claudia; Pohanka, Erich; Martin, Pierre-Yves; Gerhardt, Moritz; Farese, Stefan; Neumayer, Hans-H; Floege, Juergen; Gurr, Caroline; Budde, Klemens; DACH Study Group, (2010). Impact of daclizumab, low-dose cyclosporine, mycophenolate mofetil and steroids on renal function after kidney transplantation. Nephrology, dialysis, transplantation, 25(1), pp. 283-92. Oxford: Oxford University Press 10.1093/ndt/gfp468
BACKGROUND: Early and long-term use of cyclosporine A (CsA) leads to increased risks of renal toxicity. We hypothesized that administration of daclizumab in combination with mycophenolate mofetil (MMF) allows a relevant reduction in the dose of CsA.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7743ed9fe42ee201ba38740134afade3
http://doc.rero.ch/record/303350/files/gfp468.pdf
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4
Effect of Cyclosporin A and Zidovudine on Immune Abnormalities Observed in the Murine Acquired Immunodeficiency Syndrome
Autor: Christoph H. Heusser, Shozo Izui, Ramón Merino, A. Cerny, Francis Waldvogel, S de Kossodo, Herbert C. Morse, Liliane Fossati
Publikováno v: The Journal of Infectious Diseases, Vol. 166, No 2 (1992) pp. 285-290
Scopus-Elsevier
Cerny, Andreas; Merino, Ramón; Fossati, Liliane; De Kossodo, Sylvie; Heusser, Christoph; Waldvogel, Francis A.; Morse, Herbert C.; Izui, Shozo (1992). Effect of Cyclosporin A and Zidovudine on Immune Abnormalities Observed in the Murine Acquired Immunodeficiency Syndrome. Journal of infectious diseases, 166(2), pp. 285-290. The University of Chicago Press 10.1093/infdis/166.2.285
Two therapeutic modalities, zidovudine (targeting retroviral replication) and cyclosporin A (targeting immunopathologic consequences of retroviral expression) were evaluated in a murine model of AIDS. In previous studies, cyclosporin A treatment (40
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913e6a788e87fae8b091448450bb1f18
http://doc.rero.ch/record/301259/files/166-2-285.pdf
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5
Downregulation of Akt and FAK phosphorylation reduces invasion of glioblastoma cells by impairment of MT1-MMP shuttling to lamellipodia and downregulates MMPs expression
Autor: Urszula Hibner, Maciej Lipko, Magdalena Kijewska, Bozena Kaminska, Aneta Kwiatkowska
Publikováno v: Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2011, 1813 (5), pp.655--67. ⟨10.1016/j.bbamcr.2011.01.020⟩
Human malignant glioblastomas are highly invasive tumors. Increased cell motility and degradation of the surrounding extracellular matrix are essential for tumor invasion. PI3K/Akt signaling pathway emerges as a common pathway regulating cellular pro
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6
Dynamic binding of Ku80, Ku70 and NF90 to the IL-2 promoter in vivo in activated T-cells
Autor: Guohua Zhao, Westley H. Reeves, Peter N. Kao, Daoming Qiu, Blaise Corthesy, Susan Lees-Miller, Lingfang Shi
Publikováno v: Nucleic Acids Research
Nucleic Acids Research, vol. 35, no. 7, pp. 2302-10
IL-2 gene expression in activated T-cells is initiated by chromatin remodeling at the IL-2 proximal promoter and conversion of a transcriptional repressor into a potent transcriptional activator. A purine-box regulator complex was purified from activ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154a7dd093cf5d80a764c69798b87a27
https://doi.org/10.1093/nar/gkm117
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7
Mitochondrial cytochromecrelease is a key event in hyperoxia-induced lung injury: protection by cyclosporin A
Autor: Isabelle Métrailler, Yves Donati, Alessandra Pagano, Constance Barazzone Argiroffo
Publikováno v: American Journal of Physiology. Lung Cellular and Molecular Physiology, Vol. 286, No 2 (2004) pp. L275-83
Hyperoxia is known to induce extensive alveolar cell death by still poorly defined mechanisms. In this study, the mitochondria-dependent cell death pathway was explored during hyperoxia-induced lung injury in mice. We observed a progressive release o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f875445dbb7f8cf9f44c7f8ec49bae
https://doi.org/10.1152/ajplung.00181.2003
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8
Corticosteroids Do Not Reverse the Inhibitory Effect of Cyclosporine on Regulatory T-Cell Activity in Contrast to Mycophenolate Mofetil
Autor: Yvon Calmus, Emmanuel Boleslawski, Y. de Launoit, Véronique Pancré, Lynda Aoudjehane, Nadira Delhem, L. Ouaguia, Olivier Moralès, Céline Miroux, Filomena Conti
Publikováno v: Transplantation Proceedings
Transplantation Proceedings, 2012, 44 (9), pp.2834-2839. ⟨10.1016/j.transproceed.2012.09.091⟩
Transplantation Proceedings, Elsevier, 2012, 44 (9), pp.2834-2839. ⟨10.1016/j.transproceed.2012.09.091⟩
International audience; BACKGROUND: Inevitable hepatitis C virus recurrence after liver transplantation, a major barrier to survival of the transplanted liver may be promoted by immunosuppression and by CD4(+)CD25(+) regulatory T cells (Treg). Treg c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3200b1858c131c8084716418afb0113
https://hal.archives-ouvertes.fr/hal-03059987
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10
Cyclophilin B interacts with sodium-potassium ATPase and is required for pump activity in proximal tubule cells of the kidney
Autor: Anna Meseguer, Thomas Pertel, Marta Puigmulé, Guillermo Suñé, J. López-Hellin, Madeleine Zufferey, Jeremy Luban, Eduard Sarró
Publikováno v: PLoS ONE, Vol 5, Iss 11, p e13930 (2010)
PLOS ONE, Vol. 5, No 11 (2010) P. e13930
PloS one
PLoS ONE
Cyclophilins (Cyps), the intracellular receptors for Cyclosporine A (CsA), are responsible for peptidyl-prolyl cis-trans isomerisation and for chaperoning several membrane proteins. Those functions are inhibited upon CsA binding. Albeit its great ben
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca2d5c203c6aefb18ceb624c933c562
http://europepmc.org/articles/PMC2978098?pdf=render
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