Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Cyclin-dependent kinase inhibitor 1C"'
1
Akademický článek
A Case Report of Neonatal Beckwith-Wiedemann Syndrome and Literature Review
Autor: ZENG Liuyu, YANG Xiufang
Publikováno v: Zhongguo quanke yixue, Vol 27, Iss 36, Pp 4615-4620 (2024)
Beckwith-Wiedemann syndrome (BWS) is a growth disorder in which BWS is associated with aberrant expression of genes imprinted in the critical region of BWS and is considered a clinical spectrum in which affected individuals may have many or only one
Externí odkaz: https://doaj.org/article/9d7a60a72a744faf9df56cc10e4eb07b
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2
CDKN1C‐mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib
Autor: Koichiro Inaki, Nobuaki Adachi, Suguru Fukuhara, Takuo Katsumoto, Shuhei Fujita, Daisuke Honma, Ayako Kato, Yukio Kobayashi, Kazushi Araki, Yoshimasa Ono, Kazutsune Yamagata, Yutaka Shima, Issay Kitabayashi, Kensei Tobinai, Makoto Nakagawa, Yuki Kagiyama
Publikováno v: Cancer Science
Mantle cell lymphoma (MCL) is a rare subtype of non‐Hodgkin's lymphoma, which is characterized by overexpression of cyclin D1. Although novel drugs, such as ibrutinib, show promising clinical outcomes, relapsed MCL often acquires drug resistance. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d106471a0a494a281fda6f2252d488
http://europepmc.org/articles/PMC8177787
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3
miR-92b-3p Regulates Cell Cycle and Apoptosis by Targeting CDKN1C, Thereby Affecting the Sensitivity of Colorectal Cancer Cells to Chemotherapeutic Drugs
Autor: Xiongwen Zhang, Fangqing Zhao, Lixing Feng, Xiaofan Gu, Mingshi Xu, Zhongmin Yang
Publikováno v: Cancers
Volume 13
Issue 13
Cancers, Vol 13, Iss 3323, p 3323 (2021)
Simple Summary Multidrug resistance (MDR) limits the effectiveness of colorectal cancer (CRC) treatment and miRNAs play an important role in drug resistance. To search for miRNA targets that may be involved in the CRC MDR phenotype, this study used s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee4f087fecfd98f7ede90905fc8c5b6
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5
Akademický článek
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6
Exosomes derived from M1 macrophages aggravate neointimal hyperplasia following carotid artery injuries in mice through miR-222/CDKN1B/CDKN1C pathway
Autor: Zeng Wang, Aijun Sun, Rongle Liu, Junbo Ge, Xinyu Weng, Kai Hu, Hongtao Shi, Rifeng Gao, Xiao Li, Yunzeng Zou, Hong Zhu, Huan Zhao
Publikováno v: Cell Death and Disease, Vol 10, Iss 6, Pp 1-15 (2019)
Cell Death & Disease
The role of M1 macrophages (M1M)-derived exosomes in the progression of neointimal hyperplasia remains unclear now. Using a transwell co-culture system, we demonstrated that M1M contributed to functional change of vascular smooth muscle cell (VSMC).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76b25dfc8b8c4e4fd37e832c742c040
https://doi.org/10.1038/s41419-019-1667-1
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7
LncRNA STEAP3-AS1 Modulates Cell Cycle Progression via Affecting CDKN1C Expression Through STEAP3 in Colon Cancer
Autor: Xiaomeng Li, Xiaomeng Shi, Xinsheng Zhang, Heya Na, Zihao Chen, Yunfei Zuo
Publikováno v: SSRN Electronic Journal.
Background: Previous studies have reported that lncRNAs have acted as new players during tumorigenesis by gene regulation in the transcriptional and posttranscriptional levels. Metallothionein plays an important role in tumorigenesis and progression.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b91f6119ca69235893c9e1e7e9755ef
https://doi.org/10.2139/ssrn.3377502
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8
Dysregulation of DNA methylation and expression of imprinted genes in mouse placentas of fetal growth restriction induced by maternal cadmium exposure
Autor: Zhongqiang Wu, Peng Xu, Lan Wang, Weiwei Yang
Publikováno v: Toxicology. 390
Cadmium (Cd) is one of the most toxic environmental pollutants that cause fetal malformation and growth restriction. However, the molecular mechanisms underlying maternal Cd toxicity on fetal growth remain largely unknown. Specifically, the expressio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61f651ff38e8832684d3fc474e52f30
https://pubmed.ncbi.nlm.nih.gov/28823913
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9
A type 2 diabetes-associated SNP in KCNQ1 (rs163184) modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a, potentially affecting CDKN1C expression
Autor: Kazuki Yasuda, Nobuaki Funahashi, Keisuke Miyazawa, Haruhide Udagawa, Eri Takahashi, Naoko Ishibashi, Masaki Hiramoto, Takao Nammo, Yasushi Kaburagi
Publikováno v: International Journal of Molecular Medicine
Although genome-wide association studies have shown that potassium voltage-gated channel subfamily Q member 1 (KCNQ1) is one of the genes that is most significantly associated with type 2 diabetes mellitus (T2DM), functionally annotating disease-asso
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7865ffab67d3584746446da05b700973
https://pubmed.ncbi.nlm.nih.gov/29207083
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10
Akademický článek
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