Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Cyclin-abhängige Kinasen"'
Autor:
Sun, Guoxin
The cardiomyocytes of zebrafish can regenerate in case of necrosis. Several studies have shown that the Bone morphogenetic signaling pathway (BMP signaling) is involved in the process of zebrafish heart regeneration. To identify candidate mediators o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a331e9bcc01454ee31fae970abab1d4
Autor:
Schütz, Martin, Müller, Regina, Socher, Eileen, Wangen, Christina, Full, Florian, Wyler, Emanuel, Wong, Diana, Scherer, Myriam, Stamminger, Thomas, Chou, Sunwen, Rawlinson, William D., Hamilton, Stuart T., Sticht, Heinrich, Marschall, Manfred, Kurokawa, Manae Suzuki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3587::28488e9c0cc27b8cf4deafad9ad01308
Autor:
Shen, Xiao
Background: Colorectal cancer (CRC) still remains one of the deadliest malignancies in the world for both men and women. The development of resistance to cytotoxic and targeted therapies remains the primary reason for treatment failures. A novel ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf2dfc0986f710dea5d97d818798be8
Feasibility of adjuvant treatment with abemaciclib—real-world data from a large german breast center
Autor:
Dannehl, Dominik, Volmer, Lea L., Weiss, Martin, Matovina, Sabine, Grischke, Eva-Maria, Oberlechner, Ernst, Seller, Anna, Walter, Christina B., Hahn, Markus, Engler, Tobias, Brucker, Sara Y., Hartkopf, Andreas D., Schwab, Matthias, Schroth, Werner
Abemaciclib significantly improves invasive disease-free survival when combined with endocrine therapy in clinical high-risk patients with HR+/Her2− early breast cancer (eBC). The objective of the following study was to model how many patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f996369ec21edde6572c914d53423b5c
Autor:
Beyer, Carsten
The rapid development of high performance computing systems and the decreasing costs of hardware components allow the combination of these technologies in structure based drug design. A promising approach for this application is the networked deploym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::51c6ebb5777b56d875a41f2a2c0613b7
https://hdl.handle.net/10900/124192
https://hdl.handle.net/10900/124192
Autor:
Schaum, Monika
Mitglieder der Zyklin-dependent-Kinase (CDK)-Familie sind an verschiedenen zellulären Prozessen beteiligt. Da eine Dysregulation verschiedener CDKs zur Entstehung maligner Tumoren beitragen kann stellen sie interessante Zielmoleküle für eine zielg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acdddc0d3965a6d75eda32dd06713cd7
Autor:
Pfänder, Pauline, Eiers, Ann-Kathrin, Burret, Ute, Vettorazzi, Sabine, Shenhar-Tsarfaty, Shani
Immune response control is critical as excessive cytokine production can be detrimental and damage the host. Interleukin-10 (Il-10), an anti-inflammatory cytokine produced primarily by macrophages, is a key regulator that counteracts and controls exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331783ca816d88453c38c120fbb41eaf
Autor:
Schneider, Sandra
Kolonkarzinome sind weltweit eine der häufigsten Tumorerkrankungen und sind für eine Vielzahl der jährlichen Krebstodesfälle verantwortlich. Ziel ist es daher, neue Zielstrukturen für eine gezielte und möglichst nebenwirkungsarme Tumortherapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0aef48888f583a4b34d1b817f4af610
Autor:
Böhm, Michael Johannes
Das Leiomyosarkom ist eine histologische Entität mit hoher genetischer Variabilität. Trotz stetigen intensiven Forschungsanstrengungen finden sich in einer Mehrzahl der Tumoren keine wiederkehrenden genetischen Veränderungen, sondern diese spiegel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f03e9ca06920e6fa390a48962e15a6c
Autor:
Jana Muschhammer, Dongsheng Jiang, Miray Fidan, Karin Scharffetter-Kochanek, Tabea Hein, Haifeng Ye, Juliane C. de Vries, Vasily S. Romanov, Susanne Schatz, Yuval Rinkevich
Publikováno v:
Wound Repair Regen. 28, 49-60 (2020)
Nonhealing chronic wounds in the constantly growing elderly population represent a major public health problem with high socioeconomic burden. Yet, the underlying mechanism of age���related impairment of wound healing remains elusive. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d87d0aab1e660d0ef776b8aa0931db8
https://pubmed.ncbi.nlm.nih.gov/31571377
https://pubmed.ncbi.nlm.nih.gov/31571377
