Zobrazeno 1 - 10
of 908
pro vyhledávání: '"Cyclin E1"'
Autor:
Wataru Fukumoto, Shunsuke Okamura, Motoki Tamai, Junya Arima, Ichiro Kawahara, Ikumi Fukuda, Akihiko Mitsuke, Takashi Sakaguchi, Satoshi Sugita, Ryosuke Matsushita, Shuichi Tatarano, Yasutoshi Yamada, Masayuki Nakagawa, Hideki Enokida, Hirofumi Yoshino
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Chemotherapy including cisplatin is recommended for the treatment of advanced bladder cancer, but its effectiveness is limited due to the acquisition of drug resistance. Although several mechanisms of cisplatin resistance have bee
Externí odkaz:
https://doaj.org/article/7d46651dce6b448899636a311a74c173
Autor:
Andra S. Martinikova, Miroslav Stoyanov, Anna Oravetzova, Yannick P. Kok, Shibo Yu, Jana Dobrovolna, Pavel Janscak, Marcel vanVugt, Libor Macurek
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 6-20 (2024)
Oncogene‐induced replication stress has been recognized as a major cause of genome instability in cancer cells. Increased expression of cyclin E1 caused by amplification of the CCNE1 gene is a common cause of replication stress in various cancers.
Externí odkaz:
https://doaj.org/article/bca8c70888bf4c5eb9181c8b76ab63bf
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Diar Aziz, Christine Lee, Venessa Chin, Kristine J Fernandez, Zoe Phan, kConFab Investigators, AOCS Study Group, Paul Waring, C Elizabeth Caldon
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 4, Pp 355-370 (2022)
Abstract Basal‐like breast cancer (BLBC) has a greater overlap in molecular features with high‐grade serous ovarian cancer (HGSOC) than with other breast cancer subtypes. Similarities include BRCA1 mutation, high frequency of TP53 mutation, and a
Externí odkaz:
https://doaj.org/article/a5b727e7474c49bbb67d277f89421abf
Autor:
Md. Asad Ullah, Maisha Farzana, Md. Shariful Islam, Ripa Moni, Umme Salma Zohora, Mohammad Shahedur Rahman
Publikováno v:
Heliyon, Vol 8, Iss 9, Pp e10367- (2022)
Cyclin E1 (CCNE1) is a protein-coding gene that belongs to the Cyclin family of genes which controls the G1/S phase transition of the cell cycle. Previously, its abnormal expression pattern has been examined and found to be correlated with ovarian an
Externí odkaz:
https://doaj.org/article/9ad62ecfcb2c44f7b8c5c30c66fd0532
Autor:
Oscar Del Moral-Hernández, Daniel Hernández-Sotelo, Luz del Carmen Alarcón-Romero, Miguel Angel Mendoza-Catalán, Eugenia Flores-Alfaro, Yaneth Castro-Coronel, Julio Ortiz-Ortiz, Marco Antonio Leyva-Vázquez, Carlos Ortuño-Pineda, Wendy Castro-Mora, Berenice Illades-Aguiar
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background To improve the efficiency of early diagnosis systems for cervical cancer, the use of cellular and viral markers for identifying precancerous lesions with a greater probability to progress to cancer has been proposed. Several cellu
Externí odkaz:
https://doaj.org/article/912808ca23ac4c0da7a4f3c3f5c081e8
Autor:
Angela MY Chan, Emeka Enwere, John B McIntyre, Holly Wilson, Chidera Nwaroh, Nicholas Wiebe, Young Ou, Shuhong Liu, Katharina Wiedemeyer, Peter F Rambau, Xin Grevers, Donald G Morris, Paola Neri, C Blake Gilks, Frank Visser, Nhu Le, Li Luo, Linda S Cook, Martin Köbel
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 6, Iss 4, Pp 252-262 (2020)
Abstract CCNE1 amplification is a recurrent alteration associated with unfavourable outcome in tubo‐ovarian high‐grade serous carcinoma (HGSC). We aimed to investigate whether immunohistochemistry (IHC) can be used to identify CCNE1 amplification
Externí odkaz:
https://doaj.org/article/6ee18146a012411aa9e07aebf83b2262
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-17 (2020)
Abstract Background Mesenchymal stem cells (MSCs) are pluripotent mesenchymal cells present in various adult tissues. MSCs secrete exosomes as regulators of the tumor niche, with involvement in tumorigenesis and metastasis. The regulatory role of mic
Externí odkaz:
https://doaj.org/article/6cc1bf491d7241629bf6bd30ac27587f