Zobrazeno 1 - 10
of 1 367
pro vyhledávání: '"CyTOF"'
Autor:
Diwenxin Zhou, Shuai Zhao, Keting He, Qiuhong Liu, Fen Zhang, Zhangya Pu, Lanlan Xiao, Lingjian Zhang, Shangci Chen, Xiaohan Qian, Xiaoxin Wu, Yangfan Shen, Ling Yu, Huafen Zhang, Jiandi Jin, Min Xu, Xiaoyan Wang, Danhua Zhu, Zhongyang Xie, Xiaowei Xu
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract This study investigates the longitudinal dynamic changes in immune cells in COVID-19 patients over an extended period after recovery, as well as the interplay between immune cells and antibodies. Leveraging single-cell mass spectrometry, we
Externí odkaz:
https://doaj.org/article/9eb33381005d49b19b06543e6402c2f3
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-27 (2024)
Abstract Advancements in cytometry technologies have enabled quantification of up to 50 proteins across millions of cells at single cell resolution. Analysis of cytometry data routinely involves tasks such as data integration, clustering, and dimensi
Externí odkaz:
https://doaj.org/article/a9bd3be5af234d1f83222096912f9606
Autor:
Xiaolong Ya, Chenglong Liu, Long Ma, Peicong Ge, Xiaoxue Xu, Zhiyao Zheng, Siqi Mou, Rong Wang, Qian Zhang, Xun Ye, Dong Zhang, Yan Zhang, Wenjing Wang, Hao Li, Jizong Zhao
Publikováno v:
MedComm, Vol 5, Iss 8, Pp n/a-n/a (2024)
Abstract Previous studies have found that the peripheral immune environment is closely related to the occurrence and development of intracranial aneurysms. However, it remains unclear how the metabolism of peripheral blood mononuclear cells (PBMCs) a
Externí odkaz:
https://doaj.org/article/8b51b431faf44120b31e0931f3e0656a
Autor:
Job Saris, Sanne Bootsma, Jan Verhoeff, Jurriaan B. Tuynman, Manon E. Wildenberg, Esther Siteur-van Rijnstra, Kristiaan J. Lenos, Juan J. Garcia Vallejo, Louis Vermeulen, Joep Grootjans
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe occurrence of peritoneal metastasis (PM) in patients with colorectal cancer (CRC) has a dismal prognosis. There is often limited response to systemic- and immunotherapy, even in microsatellite unstable (MSI) CRC. To overcome therapy res
Externí odkaz:
https://doaj.org/article/0db70c82f5d3425981c96647ff398c29
Autor:
Xinlei He, Xiao Cui, Zhiling Zhao, Rui Wu, Qiang Zhang, Lei Xue, Hua Zhang, Qinggang Ge, Yuxin Leng
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe coronavirus disease 2019 (COVID-19) pandemic has affected billions of people worldwide, and the lessons learned need to be concluded to get better prepared for the next pandemic. Early identification of high-risk patients is important
Externí odkaz:
https://doaj.org/article/d613922f7bfc444b942c3e82efcdbe51
Autor:
Nan Shao, Chenshuo Ren, Tianyuan Hu, Dianbing Wang, Xiaofan Zhu, Min Li, Tao Cheng, Yingchi Zhang, Xian-En Zhang
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Background Acute myeloid leukaemia (AML) is characterised by the malignant accumulation of myeloid progenitors with a high recurrence rate after chemotherapy. Blasts (leukaemia cells) exhibit a complete myeloid differentiation hierarchy hidi
Externí odkaz:
https://doaj.org/article/d0b7353eb9f34c9db8be013bdc62389d
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-29 (2023)
Abstract Recently, many analysis tools have been devised to offer insights into data generated via cytometry by time-of-flight (CyTOF). However, objective evaluations of these methods remain absent as most evaluations are conducted against real data
Externí odkaz:
https://doaj.org/article/a3839d0cd8694de1a0a173285a5bf760
Autor:
Xiaolong Ya, Long Ma, Chenglong Liu, Peicong Ge, Yiqiao Xu, Zhiyao Zheng, Siqi Mou, Rong Wang, Qian Zhang, Xun Ye, Dong Zhang, Yan Zhang, Wenjing Wang, Hao Li, Jizong Zhao
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Background Intracranial aneurysms (IAs) represent a severe cerebrovascular disease that can potentially lead to subarachnoid haemorrhage. Previous studies have demonstrated the involvement of peripheral immune cells in the formation and prog
Externí odkaz:
https://doaj.org/article/d5b880c11904405aa233fa0548c89497
Autor:
Kathrin Balz, Magali Grange, Uta Pegel, Zain A. Karamya, Marielle Mello, Xiaoying Zhou, Thilo Berger, Konstantin Bloch, Diane Dunham, Sharon Chinthrajah, Kari Nadeau, Hervé Luche, Chrysanthi Skevaki
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)
Understanding antigen-specific T-cell responses, for example, following virus infections or allergen exposure, is of high relevance for the development of vaccines and therapeutics. We aimed on optimizing immunophenotyping of T cells after antigen st
Externí odkaz:
https://doaj.org/article/cd666241a2b54fa2b38d3d9aa950af30
Autor:
Jennifer Connors, Gina Cusimano, Nathan Mege, Kyra Woloszczuk, Emily Konopka, Matthew Bell, David Joyner, Jennifer Marcy, Virginie Tardif, Michele A. Kutzler, Roshell Muir, Elias K. Haddad
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 3 (2023)
In the field of immunology, a systems biology approach is crucial to understanding the immune response to infection and vaccination considering the complex interplay between genetic, epigenetic, and environmental factors. Significant progress has bee
Externí odkaz:
https://doaj.org/article/c0f6d54dbefc41c98846e72a4e1051a7