How does lateral tilting affect the internal strains in the sacral region of bed ridden patients? : a contribution to pressure ulcer prevention

Autor: Baukje Hemmes, Cwj Cees Oomens, M Merel Broek, Dan L. Bader

Publikováno v: Clinical Biomechanics, 35, 7-13. Elsevier

Background Repositioning of individuals with reduced mobility and at risk of pressure ulcers is an essential preventive step. Manual or automatic lateral tilting is a way of doing this and the international guidelines propose a 30° to 40° side lyin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b7ad0a1e6ef979a723ff5df0691791
https://doi.org/10.1016/j.clinbiomech.2016.03.009

A theoretical compartment model for antigen kinetics in the skin

Autor: AM Anne Römgens, Cwj Cees Oomens, Joke A. Bouwstra, Dan L. Bader

Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
European Journal of Pharmaceutical Sciences, 84, 18-25. Elsevier

The skin is a promising location for vaccination with its abundant population ofantigen capturing and presenting cells. The development of new techniques, suchas the use of microneedles, can facilitate the delivery of vaccines into theskin. In recent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92c587e3371db9fbe9ef20eb4ad2f65
https://doi.org/10.1016/j.ejps.2016.01.007

Modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues

Autor: G Giulia Argento, de N Nicky Jonge, Frank Frank Baaijens, Cwj Cees Oomens, Carlijn V. C. Bouten, Shm Serge Söntjens

Publikováno v: Biomechanics and Modeling in Mechanobiology, 14(3), 603-613. Springer

The anisotropic collagen architecture of an engineered cardiovascular tissue has a major impact on its in vivo mechanical performance. This evolving collagen architecture is determined by initial scaffold microstructure and mechanical loading. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3b7fdb3475cd534d994eb28066fa8e
http://www.scopus.com/inward/record.url?scp=84939888078&partnerID=8YFLogxK

Diphtheria toxoid and N-trimethyl chitosan layer-by-layer coated pH-sensitive microneedles induce potent immune responses upon dermal vaccination in mice

Autor: Vincent Groeneveld, Koen van der Maaden, Pim Schipper, Gideon F.A. Kersten, Stefan Romeijn, Joke A. Bouwstra, Mitchel Ruigrok, Wim Jiskoot, Sven Uleman, Cwj Cees Oomens

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society
Journal of Controlled Release, 262, 28-36. Elsevier
JOURNAL OF CONTROLLED RELEASE, 262, 28-36

Dermal immunization using antigen-coated microneedle arrays is a promising vaccination strategy. However, reduction of microneedle sharpness and the available surface area for antigen coating is a limiting factor. To overcome these obstacles, a layer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286607858027df7812e69d244912ad31
https://pubmed.ncbi.nlm.nih.gov/28710002

Compressive mechanical properties of atherosclerotic plaques-Indentation test to characterise the local anisotropic behaviour

Autor: C-K Chen-Ket Chai, Lambert Speelman, Cwj Cees Oomens, Frank Frank Baaijens

Publikováno v: Journal of Biomechanics, 47(4), 784-792. Elsevier

Accurate material models and associated parameters of atherosclerotic plaques are crucial for reliable biomechanical plaque prediction models. These biomechanical models have the potential to increase our understanding of plaque progression and failu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5caf79ca38f82703c27d077969342cd8
https://doi.org/10.1016/j.jbiomech.2014.01.018