Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cvetan Stojkoski"'
Autor:
Abdussalam Adina-Zada, Steven W. Polyak, W. Wallace Cleland, Grant W. Booker, Katharina H. Surinya, Sarawut Jitrapakdee, Cvetan Stojkoski, Paul V. Attwood, Roger Smyth, John C. Wallace
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 39:2120-2134
The native form of pyruvate carboxylase is an alpha4 tetramer but the tetramerisation domain of each subunit is currently unknown. To identify this domain we co-expressed yeast pyruvate carboxylase 1 isozyme (Pyc1) with an N-terminal myc tag, togethe
Autor:
Diana G. Salerno, Richard J D'Andrea, Anna L. Brown, Cvetan Stojkoski, Thomas J. Gonda, Angel F. Lopez, Margaret L. Hibbs, Grant W. Booker, Michelle Perugini, Timothy R. Hercus
Granulocyte/macrophage colony-stimulating factor promotes growth, survival, differentiation, and activation of normal myeloid cells and plays an important role in myeloid leukemias. The GM-CSF receptor (GMR) shares a signaling subunit, βc, with inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8821712804f72625385f57e98a9271a
https://hdl.handle.net/1959.8/155075
https://hdl.handle.net/1959.8/155075
Autor:
A. David Frenkel, Caroline Dive, Grant W. Booker, Noor Atatreh, Sally Freeman, P Smith, Richard A. Bryce, Cvetan Stojkoski
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(3)
Src signalling and transduction are directly involved in cell growth, cell cycle, malignant transformation and cell migration, providing therapeutic opportunities through inhibition of Src. Here we report virtual screening for novel compounds that in
Autor:
Simon M. Pyke, Rhiannon K. Jones, Grant W. Booker, Steven R. Inglis, Daniel Fritz, Cvetan Stojkoski
Publikováno v:
Organicbiomolecular chemistry. 3(14)
The Src homology 3 (SH3) domains are small protein-protein interaction domains that mediate a range of important biological processes and are considered valuable targets for the development of therapeutic agents. We have been developing 2-aminoquinol
Autor:
Steven R. Inglis, Simon M. Pyke, Jacquie F Cawthray, Emma Wiadrowski, Grant W. Booker, Kim M. Branson, Cvetan Stojkoski, Daniel Fritz
Publikováno v:
Journal of medicinal chemistry. 47(22)
The Src Homology 3 (SH3) domains are small protein-protein interaction domains that bind proline-rich sequences and mediate a wide range of cell-signaling and other important biological processes. Since deregulated signaling pathways form the basis o
Autor:
Murray L. Whitelaw, Robyn J. Kewley, Cvetan Stojkoski, Sarah Linke, Grant W. Booker, Daniel J. Peet
Publikováno v:
The Journal of biological chemistry. 279(14)
The hypoxia-inducible factor alpha subunits 1 and 2 (HIF-1alpha and HIF-2alpha) are subjected to oxygen-dependent asparaginyl hydroxylation, a modification that represses the carboxyl-terminal transactivation domain (CAD) at normoxia by preventing re