Reanalysing genomic data by normalized coverage values uncovers CNVs in bone marrow failure gene panels.

Autor: Lauhasurayotin S; 1Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON Canada.; 2Marrow Failure and Myelodysplasia Program, Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON Canada., Cuvelier GD; 3Pediatric Hematology-Oncology-Bone Marrow Transplantation, University of Manitoba, Cancer Care Manitoba, Winnipeg, MB Canada., Klaassen RJ; 4Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, ON Canada., Fernandez CV; 5Pediatric Hematology/Oncology, IWK Health Centre, Halifax, NS Canada., Pastore YD; 6CHU Sainte-Justine, Montreal, QC Canada., Abish S; 7Pediatric Hematology Oncology, Montreal Children's Hospital, Montreal, QC Canada., Rayar M; 8Division of Hematology/Oncology, UBC & B.C. Children's Hospital, Vancouver, BC Canada., Steele M; 9Alberta Children's Hospital, Calgary, Canada., Jardine L; 10Children's Hospital, London Health Sciences Centre, London, ON Canada., Breakey VR; 11Department of Pediatrics, McMaster University, Hamilton, ON Canada., Brossard J; 12Centre hospitalier universitaire, Sherbrooke, QC Canada., Sinha R; 13Royal University Hospital, Saskatoon, SK Canada., Silva M; 14Kingston General Hospital, Kingston, ON Canada., Goodyear L; 15Pediatric Hematology/Oncology, Janeway Child Health Centre, St. John's, NF Canada., Lipton JH; 16Allogeneic Blood and Marrow Transplant Program, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON Canada., Michon B; 17Centre Hospitalier Universitaire de Quebec, Sainte-Foy, QC Canada., Corriveau-Bourque C; 18Pediatrics, University of Alberta, Edmonton, AB Canada., Sung L; 19Population Health Sciences, Research Institute, Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON Canada., Shabanova I; 1Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON Canada., Li H; 1Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON Canada., Zlateska B; 1Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON Canada., Dhanraj S; 1Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON Canada.; 20Institute of Medical Science, University of Toronto, Toronto, ON Canada., Cada M; 2Marrow Failure and Myelodysplasia Program, Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON Canada., Scherer SW; 1Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON Canada.; 21McLaughlin Centre and Department of Molecular Genetics, University of Toronto, Toronto, ON Canada., Dror Y; 1Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON Canada.; 2Marrow Failure and Myelodysplasia Program, Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON Canada.; 20Institute of Medical Science, University of Toronto, Toronto, ON Canada.

Publikováno v: NPJ genomic medicine [NPJ Genom Med] 2019 Dec 09; Vol. 4, pp. 30. Date of Electronic Publication: 2019 Dec 09 (Print Publication: 2019).

Transplantation-associated thrombotic microangiopathy isolated to a congenital anomaly of the lung.

Autor: Kummen RT; Section of Pediatric Hematology/Oncology, Department of Pediatrics and Child Health, University of Manitoba and Health Sciences Centre, Winnipeg, Manitoba, Canada., Cuvelier GD; Section of Pediatric Hematology/Oncology, Department of Pediatrics and Child Health, University of Manitoba and Health Sciences Centre, Winnipeg, Manitoba, Canada.; Manitoba Blood and Marrow Transplant Program, CancerCare Manitoba, Winnipeg, Manitoba, Canada., Stefanovici C; Department of Pathology, University of Manitoba and Diagnostic Services of Manitoba, Health Sciences Centre, Winnipeg, Manitoba, Canada., Perry AM; Department of Pathology, University of Manitoba and Diagnostic Services of Manitoba, Health Sciences Centre, Winnipeg, Manitoba, Canada., Higgins R; Department of Radiology, University of Manitoba and Health Sciences Centre, Winnipeg, Manitoba, Canada., Yanofsky R; Section of Pediatric Hematology/Oncology, Department of Pediatrics and Child Health, University of Manitoba and Health Sciences Centre, Winnipeg, Manitoba, Canada., Lum Min SA; Department of Surgery, University of Manitoba and Health Sciences Centre, Winnipeg, Manitoba, Canada., Wall DA; Section of Pediatric Hematology/Oncology, Department of Pediatrics and Child Health, University of Manitoba and Health Sciences Centre, Winnipeg, Manitoba, Canada.; Manitoba Blood and Marrow Transplant Program, CancerCare Manitoba, Winnipeg, Manitoba, Canada.; Department of Internal Medicine, University of Manitoba and Health Sciences Centre, Winnipeg, Manitoba, Canada.

Publikováno v: Pediatric transplantation [Pediatr Transplant] 2017 Feb; Vol. 21 (1). Date of Electronic Publication: 2016 Nov 24.

Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis.

Autor: Bartelink IH; Department of Medicine, University of California San Francisco, CA, USA., Lalmohamed A; Clinical Pharmacy Department, University Medical Center Utrecht, Utrecht, Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, Netherlands., van Reij EM; Clinical Pharmacy Department, University Medical Center Utrecht, Utrecht, Netherlands., Dvorak CC; Pediatric Allergy, Immunology, and Bone Marrow Transplantation Division, University of California San Francisco, CA, USA., Savic RM; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, CA, USA., Zwaveling J; Leiden University Medical Center, Leiden, Netherlands., Bredius RG; Leiden University Medical Center, Leiden, Netherlands., Egberts AC; Clinical Pharmacy Department, University Medical Center Utrecht, Utrecht, Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, Netherlands., Bierings M; Division of Pediatrics, Blood and Marrow Transplantation Program, University Medical Center Utrecht, Utrecht, Netherlands., Kletzel M; Stem Cell Transplant Program, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA., Shaw PJ; Division of Blood and Marrow Transplantation, The Children's Hospital at Westmead, Sydney, NSW, Australia., Nath CE; Division of Blood and Marrow Transplantation, The Children's Hospital at Westmead, Sydney, NSW, Australia., Hempel G; Department of Clinical Pharmacy, Westfälische Wilhelms-Universität Münster, Institut für Pharmazeutische und Medizinische Chemie, Münster, Germany., Ansari M; Département de l'Enfant et de l'Adolescent, Hôpital des Enfants, Geneva, Switzerland., Krajinovic M; Charles-Bruneau Cancer Center, Department of Pediatrics, Faculty of Medicine, University of Montreal, Montreal, QC, Canada., Théorêt Y; Department of Pharmacology, University of Montreal, Montreal, QC, Canada; Clinical Pharmacology Unit, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada., Duval M; Charles-Bruneau Cancer Center, Department of Pediatrics, Faculty of Medicine, University of Montreal, Montreal, QC, Canada., Keizer RJ; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, CA, USA; InsightRX, San Francisco, CA, USA., Bittencourt H; Charles-Bruneau Cancer Center, Department of Pediatrics, Faculty of Medicine, University of Montreal, Montreal, QC, Canada., Hassan M; Division of Experimental Cancer Medicine, Clinical Research Centre, Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden., Güngör T; Division of Stem Cell Transplantation and Children's Research Center, University Children's Hospital Zürich, Zürich, Switzerland., Wynn RF; Department of Haematology and Bone Marrow Transplantation, The Royal Manchester Children's Hospital, Manchester, UK., Veys P; Bone Marrow Transplantation Department, Great Ormond Street Hospital for Children, London, UK., Cuvelier GD; CancerCare Manitoba, Winnipeg, MB, Canada., Marktel S; Stem Cell Program, IRCCS San Raffaele Scientific Institute, Milan, Italy., Chiesa R; Bone Marrow Transplantation Department, Great Ormond Street Hospital for Children, London, UK; Stem Cell Program, IRCCS San Raffaele Scientific Institute, Milan, Italy., Cowan MJ; Pediatric Allergy, Immunology, and Bone Marrow Transplantation Division, University of California San Francisco, CA, USA., Slatter MA; The Institute of Cellular Medicine, Newcastle University, Newcastle, UK., Stricherz MK; Department of Hematopoietic Cell Transplant, Hematology, and Oncology, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA., Jennissen C; Department of Hematopoietic Cell Transplant, Hematology, and Oncology, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA., Long-Boyle JR; Department of Clinical Pharmacy, University of California San Francisco, CA, USA., Boelens JJ; Division of Pediatrics, Blood and Marrow Transplantation Program, University Medical Center Utrecht, Utrecht, Netherlands; Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands. Electronic address: j.j.boelens@umcutrecht.nl.

Publikováno v: The Lancet. Haematology [Lancet Haematol] 2016 Nov; Vol. 3 (11), pp. e526-e536. Date of Electronic Publication: 2016 Oct 13.

Accrual of adolescents and young adults with cancer to clinical trials.

Autor: Hay AE; Canadian Cancer Trials Group and Department of Medicine, Queen's University, Kingston, ON;, Rae C; McMaster University, Hamilton, ON;, Fraser GA; Department of Oncology, McMaster University, and the Juravinski Hospital and Cancer Centre, Hamilton, ON;, Meyer RM; Department of Oncology, McMaster University, and the Juravinski Hospital and Cancer Centre, Hamilton, ON;, Abbott LS; Division of Hematology/Oncology, Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, ON;, Bevan S; Canadian Cancer Society, Toronto, ON;, McBride ML; BC Cancer Agency, University of British Columbia, Vancouver, BC;, Cuvelier GD; Department of Pediatrics and Child Health, University of Manitoba, and CancerCare Manitoba, Winnipeg, MB;, McKillop S; Department of Pediatrics, Alberta Health Services, Calgary, AB;, Barr RD; Department of Pediatrics, McMaster University, Hamilton, ON.

Publikováno v: Current oncology (Toronto, Ont.) [Curr Oncol] 2016 Apr; Vol. 23 (2), pp. e81-5. Date of Electronic Publication: 2016 Apr 13.

Toxic epidermal necrolysis and hemophagocytic lymphohistiocytosis: a case report and literature review.

Autor: Sniderman JD; Department of Pediatrics and Child Health, University of Manitoba Winnipeg, Manitoba, Canada., Cuvelier GD; Department of Pediatrics and Child Health, University of Manitoba Winnipeg, Manitoba, Canada ; Pediatric Hematoloy-Oncology-BMT, CancerCare Manitoba Winnipeg, Manitoba, Canada., Veroukis S; Department of Pediatrics and Child Health, University of Manitoba Winnipeg, Manitoba, Canada ; Pediatric Intensive Care, Winnipeg Children's Hospital Winnipeg, Manitoba, Canada., Hansen G; Department of Pediatrics and Child Health, University of Manitoba Winnipeg, Manitoba, Canada ; Pediatric Intensive Care, Winnipeg Children's Hospital Winnipeg, Manitoba, Canada.

Publikováno v: Clinical case reports [Clin Case Rep] 2015 Feb; Vol. 3 (2), pp. 121-5. Date of Electronic Publication: 2014 Nov 17.