Overexpression of Anti-Müllerian Hormone Disrupts Gonadal Sex Differentiation, Blocks Sex Hormone Synthesis, and Supports Cell Autonomous Sex Development in the Chicken.

Autor: Lambeth LS; Murdoch Childrens Research Institute (L.S.L., K.L.A., A.H.S., A.D.C.), Royal Children's Hospital, Melbourne, Victoria 3052, Australia; Department of Paediatrics (K.L.A., A.H.S., A.D.C.), The University of Melbourne, Melbourne, Victoria 3010, Australia; Commonwealth Scientific and Industrial Research Organisation Biosecurity Flagship (K.M., T.G.W., T.O., D.W., Y.C., T.J.D.), Australian Animal Health Laboratory, Geelong, Victoria 3217, Australia; and Department of Anatomy and Developmental Biology (C.A.S.), Monash University, Clayton, Victoria 3168, Australia., Morris K; Murdoch Childrens Research Institute (L.S.L., K.L.A., A.H.S., A.D.C.), Royal Children's Hospital, Melbourne, Victoria 3052, Australia; Department of Paediatrics (K.L.A., A.H.S., A.D.C.), The University of Melbourne, Melbourne, Victoria 3010, Australia; Commonwealth Scientific and Industrial Research Organisation Biosecurity Flagship (K.M., T.G.W., T.O., D.W., Y.C., T.J.D.), Australian Animal Health Laboratory, Geelong, Victoria 3217, Australia; and Department of Anatomy and Developmental Biology (C.A.S.), Monash University, Clayton, Victoria 3168, Australia., Ayers KL; Murdoch Childrens Research Institute (L.S.L., K.L.A., A.H.S., A.D.C.), Royal Children's Hospital, Melbourne, Victoria 3052, Australia; Department of Paediatrics (K.L.A., A.H.S., A.D.C.), The University of Melbourne, Melbourne, Victoria 3010, Australia; Commonwealth Scientific and Industrial Research Organisation Biosecurity Flagship (K.M., T.G.W., T.O., D.W., Y.C., T.J.D.), Australian Animal Health Laboratory, Geelong, Victoria 3217, Australia; and Department of Anatomy and Developmental Biology (C.A.S.), Monash University, Clayton, Victoria 3168, Australia., Wise TG; Murdoch Childrens Research Institute (L.S.L., K.L.A., A.H.S., A.D.C.), Royal Children's Hospital, Melbourne, Victoria 3052, Australia; Department of Paediatrics (K.L.A., A.H.S., A.D.C.), The University of Melbourne, Melbourne, Victoria 3010, Australia; Commonwealth Scientific and Industrial Research Organisation Biosecurity Flagship (K.M., T.G.W., T.O., D.W., Y.C., T.J.D.), Australian Animal Health Laboratory, Geelong, Victoria 3217, Australia; and Department of Anatomy and Developmental Biology (C.A.S.), Monash University, Clayton, Victoria 3168, Australia., O'Neil T; Murdoch Childrens Research Institute (L.S.L., K.L.A., A.H.S., A.D.C.), Royal Children's Hospital, Melbourne, Victoria 3052, Australia; Department of Paediatrics (K.L.A., A.H.S., A.D.C.), The University of Melbourne, Melbourne, Victoria 3010, Australia; Commonwealth Scientific and Industrial Research Organisation Biosecurity Flagship (K.M., T.G.W., T.O., D.W., Y.C., T.J.D.), Australian Animal Health Laboratory, Geelong, Victoria 3217, Australia; and Department of Anatomy and Developmental Biology (C.A.S.), Monash University, Clayton, Victoria 3168, Australia., Wilson S; Murdoch Childrens Research Institute (L.S.L., K.L.A., A.H.S., A.D.C.), Royal Children's Hospital, Melbourne, Victoria 3052, Australia; Department of Paediatrics (K.L.A., A.H.S., A.D.C.), The University of Melbourne, Melbourne, Victoria 3010, Australia; Commonwealth Scientific and Industrial Research Organisation Biosecurity Flagship (K.M., T.G.W., T.O., D.W., Y.C., T.J.D.), Australian Animal Health Laboratory, Geelong, Victoria 3217, Australia; and Department of Anatomy and Developmental Biology (C.A.S.), Monash University, Clayton, Victoria 3168, Australia., Cao Y; Murdoch Childrens Research Institute (L.S.L., K.L.A., A.H.S., A.D.C.), Royal Children's Hospital, Melbourne, Victoria 3052, Australia; Department of Paediatrics (K.L.A., A.H.S., A.D.C.), The University of Melbourne, Melbourne, Victoria 3010, Australia; Commonwealth Scientific and Industrial Research Organisation Biosecurity Flagship (K.M., T.G.W., T.O., D.W., Y.C., T.J.D.), Australian Animal Health Laboratory, Geelong, Victoria 3217, Australia; and Department of Anatomy and Developmental Biology (C.A.S.), Monash University, Clayton, Victoria 3168, Australia., Sinclair AH; Murdoch Childrens Research Institute (L.S.L., K.L.A., A.H.S., A.D.C.), Royal Children's Hospital, Melbourne, Victoria 3052, Australia; Department of Paediatrics (K.L.A., A.H.S., A.D.C.), The University of Melbourne, Melbourne, Victoria 3010, Australia; Commonwealth Scientific and Industrial Research Organisation Biosecurity Flagship (K.M., T.G.W., T.O., D.W., Y.C., T.J.D.), Australian Animal Health Laboratory, Geelong, Victoria 3217, Australia; and Department of Anatomy and Developmental Biology (C.A.S.), Monash University, Clayton, Victoria 3168, Australia., Cutting AD; Murdoch Childrens Research Institute (L.S.L., K.L.A., A.H.S., A.D.C.), Royal Children's Hospital, Melbourne, Victoria 3052, Australia; Department of Paediatrics (K.L.A., A.H.S., A.D.C.), The University of Melbourne, Melbourne, Victoria 3010, Australia; Commonwealth Scientific and Industrial Research Organisation Biosecurity Flagship (K.M., T.G.W., T.O., D.W., Y.C., T.J.D.), Australian Animal Health Laboratory, Geelong, Victoria 3217, Australia; and Department of Anatomy and Developmental Biology (C.A.S.), Monash University, Clayton, Victoria 3168, Australia., Doran TJ; Murdoch Childrens Research Institute (L.S.L., K.L.A., A.H.S., A.D.C.), Royal Children's Hospital, Melbourne, Victoria 3052, Australia; Department of Paediatrics (K.L.A., A.H.S., A.D.C.), The University of Melbourne, Melbourne, Victoria 3010, Australia; Commonwealth Scientific and Industrial Research Organisation Biosecurity Flagship (K.M., T.G.W., T.O., D.W., Y.C., T.J.D.), Australian Animal Health Laboratory, Geelong, Victoria 3217, Australia; and Department of Anatomy and Developmental Biology (C.A.S.), Monash University, Clayton, Victoria 3168, Australia., Smith CA; Murdoch Childrens Research Institute (L.S.L., K.L.A., A.H.S., A.D.C.), Royal Children's Hospital, Melbourne, Victoria 3052, Australia; Department of Paediatrics (K.L.A., A.H.S., A.D.C.), The University of Melbourne, Melbourne, Victoria 3010, Australia; Commonwealth Scientific and Industrial Research Organisation Biosecurity Flagship (K.M., T.G.W., T.O., D.W., Y.C., T.J.D.), Australian Animal Health Laboratory, Geelong, Victoria 3217, Australia; and Department of Anatomy and Developmental Biology (C.A.S.), Monash University, Clayton, Victoria 3168, Australia.

Publikováno v: Endocrinology [Endocrinology] 2016 Mar; Vol. 157 (3), pp. 1258-75. Date of Electronic Publication: 2016 Jan 25.

DMRT1 is required for Müllerian duct formation in the chicken embryo.

Autor: Ayers KL; Murdoch Childrens Research Institute, Royal Children׳s Hospital, Flemington Road, Parkville 3052, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville 3052, Victoria, Australia., Cutting AD; Murdoch Childrens Research Institute, Royal Children׳s Hospital, Flemington Road, Parkville 3052, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville 3052, Victoria, Australia., Roeszler KN; Murdoch Childrens Research Institute, Royal Children׳s Hospital, Flemington Road, Parkville 3052, Victoria, Australia., Sinclair AH; Murdoch Childrens Research Institute, Royal Children׳s Hospital, Flemington Road, Parkville 3052, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville 3052, Victoria, Australia., Smith CA; Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, 3168, Australia. Electronic address: Craig.Smith@monash.edu.

Publikováno v: Developmental biology [Dev Biol] 2015 Apr 15; Vol. 400 (2), pp. 224-36. Date of Electronic Publication: 2015 Feb 12.

The potential role of microRNAs in regulating gonadal sex differentiation in the chicken embryo.

Autor: Cutting AD; CSIRO Australian Animal Health Laboratories, Portarlington Road, Geelong, Victoria, Australia., Bannister SC, Doran TJ, Sinclair AH, Tizard MV, Smith CA

Publikováno v: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology [Chromosome Res] 2012 Jan; Vol. 20 (1), pp. 201-13.