Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Cuthbert O. Simpkins"'
Publikováno v:
Trauma Monthly. 22
Background: Arterial cannulation and intra-arterial (IA) fluid and blood resuscitation in the patients with severe shock is an easier approach compared with the intravenous (IV) access if concerns regarding the efficiency and safety of this approach
Autor:
Alex G. Cuenca, Juan Rodriguez, Kyriakos D. Papadopoulos, Everett D. Grimley, Philip A. Efron, Ricardo Ungaro, Lyle L. Moldawer, M Armbruster, Cuthbert O. Simpkins, Dina C. Nacionales
Publikováno v:
Perfusion. 28:160-166
Background: Given that micelles of lipids are colloids, the hypothesis was generated that the rapid administration of large volumes of soybean oil micelles would be an effective perfusion fluid. We also hypothesized that oxygen loading would be enhan
Publikováno v:
Journal of Trauma: Injury, Infection & Critical Care. 63:565-572
BACKGROUND We previously demonstrated that the degradation of a suspension of Jurkat cells in Ringer's lactate (RL) was inhibited by the addition of a 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid/Tris buffer. Given the ability of histidine to b
Publikováno v:
Journal of Surgical Research. 75:30-34
Objective. To elucidate the effect of metallothionein on the permeability of the mitochondrial inner membrane. Background. Metallothionein (MT) is a 6–7-kDa protein which is rapidly produced by stressed cells. MT is induced by cytokines and other f
Autor:
Zhao H-Liao, J.Adrian Tyndall, Rahel Gebrehiwot, Eugene Mensah, Patricia M. Sokolove, Tekum Fonong, Cynthia A. Torrence, Cuthbert O. Simpkins, Samuel C. Balderman
Publikováno v:
Life Sciences. 58:2091-2099
Previously, we reported that the stress-induced protein metallothionein I (MT) modulated the oxygen consumption (VO2) of isolated rat liver mitochondria [Life Sci. 55 221-226, 1994]. We now present confirmation of this finding, and the additional obs
Publikováno v:
Life Sciences. 52:1487-1492
Using absorption spectroscopy, we have found that two highly conserved fragments of heat shock protein 70 reduce cytochrome c. The fragments are SCV and YSCVGVF. YSCVGVF was more potent than SCV at low concentrations (10 −6 − 10 −4 M). At high
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 879(19)
Quantitation of dissolved gases in blood or in other biological media is essential for understanding the dynamics of metabolic processes. Current detection techniques, while enabling rapid and convenient assessment of dissolved gases, provide only di
Publikováno v:
The FASEB Journal. 24
Publikováno v:
Life Sciences. 48:523-530
By observing changes in the absorbance spectrum between 340 and 650 nm, we found that tyrosyltyrosylphenylalanine (TTP) interacts with cutochrome C (CC). TTP caused the characteristic changes of CC reduction, namely, an increased optical density at 5
Publikováno v:
The Journal of trauma. 56(3)
Background: We hypothesized that by studying a suspension of a single cell type in various resuscitation fluids, we could compare their effects on parameters associated with cell death. Methods: Jurkat cells were suspended in resuscitation fluids. Us