International Validation of the Immunoscore Biopsy in Patients With Rectal Cancer Managed by a Watch-and-Wait Strategy.

Autor: El Sissy C; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Cordeliers Research Center, Sorbonne University, University Paris Cité, Paris, France.; Immunomonitoring Platform, Laboratory of Immunology, Assistance Publique-Hôpitaux de Paris (AP-HP), Georges Pompidou European Hospital, Paris, France., Kirilovsky A; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Cordeliers Research Center, Sorbonne University, University Paris Cité, Paris, France.; Immunomonitoring Platform, Laboratory of Immunology, Assistance Publique-Hôpitaux de Paris (AP-HP), Georges Pompidou European Hospital, Paris, France., Lagorce Pagès C; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Cordeliers Research Center, Sorbonne University, University Paris Cité, Paris, France.; Immunomonitoring Platform, Laboratory of Immunology, Assistance Publique-Hôpitaux de Paris (AP-HP), Georges Pompidou European Hospital, Paris, France.; Department of Pathology, AP-HP, Georges Pompidou European Hospital, Paris, France., Marliot F; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Cordeliers Research Center, Sorbonne University, University Paris Cité, Paris, France.; Immunomonitoring Platform, Laboratory of Immunology, Assistance Publique-Hôpitaux de Paris (AP-HP), Georges Pompidou European Hospital, Paris, France., Custers PA; Department of Surgery, Netherlands Cancer Institute, Antoni van Leeuwenhoek, Amsterdam, the Netherlands.; GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands., Dizdarevic E; Department of Oncology, Danish Colorectal Cancer Center South, University Hospital of Southern Denmark, Vejle, Denmark.; Department of Regional Health Research, University of Southern Denmark, Odense, Denmark., Sroussi M; Cordeliers Research Center, Sorbonne University, INSERM, University Paris Cité, SIRIC CARPEM, Paris, France.; Chemistry Biology Innovation Institute, BioChimie Laboratory, ESPCI, UMR8231 CNRS, University PSL, Paris, France., Castillo-Martin M; Department of Pathology, Fundação Champalimaud, Lisbon, Portugal., Haicheur N; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Cordeliers Research Center, Sorbonne University, University Paris Cité, Paris, France.; Immunomonitoring Platform, Laboratory of Immunology, Assistance Publique-Hôpitaux de Paris (AP-HP), Georges Pompidou European Hospital, Paris, France., Dermani M; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Cordeliers Research Center, Sorbonne University, University Paris Cité, Paris, France.; Immunomonitoring Platform, Laboratory of Immunology, Assistance Publique-Hôpitaux de Paris (AP-HP), Georges Pompidou European Hospital, Paris, France., Loche N; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Cordeliers Research Center, Sorbonne University, University Paris Cité, Paris, France.; Immunomonitoring Platform, Laboratory of Immunology, Assistance Publique-Hôpitaux de Paris (AP-HP), Georges Pompidou European Hospital, Paris, France., Buttard B; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Cordeliers Research Center, Sorbonne University, University Paris Cité, Paris, France., Musina AM; Department of Surgical Oncology, Regional Institute of Oncology (IRO), Iasi, Romania.; 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi, Romania., Anitei MG; 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi, Romania.; Surgical Oncology Unit, Regional Institute of Oncology, Iasi, Romania., van den Berg JG; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Broeks A; Core Facility Molecular Pathology and Biobanking, Netherlands Cancer Institute, Amsterdam, the Netherlands., Iseas S; Oncology Unit, Gastroenterology Hospital Carlos Bonorino Udaondo, Buenos Aires, Argentina., Coraglio M; Oncology Unit, Gastroenterology Hospital Carlos Bonorino Udaondo, Buenos Aires, Argentina., Loria FS; GI Clinical Oncology and GI Surgical Oncology, Instituto Alexander Fleming, Buenos Aires, Argentina., Romero A; Department of Clinical Oncology, British Hospital of Buenos Aires, Buenos Aires, Argentina., Laurent-Puig P; Cordeliers Research Center, Sorbonne University, University Paris Cité, INSERM UMR1138, Paris, France.; Department of Biology, Cancer Institute Paris CARPEM, AP-HP, Georges Pompidou European Hospital, Paris, France., de Reyniès A; Cordeliers Research Center, University Paris Cité, INSERM UMRS1138, Paris, France.; AP-HP, SeqOIA Genomic Medicine Laboratory-IT Platform, Paris, France., Fernandez LM; Colorectal Surgery, Digestive Department, Champalimaud Foundation, Lisbon, Portugal., Karoui M; Department of Digestive and Oncologic Surgery, AP-HP, Georges Pompidou European Hospital, Paris, France., Tougeron D; Department of Hepato-Gastro-Enterology and Nutritional Assistance, University Hospital of Poitiers, Poitiers, France., Vaccaro CA; Department of General Surgery, Hospital Italiano, Buenos Aires, Argentina., Santino JP; Department of General Surgery, Hospital Italiano, Buenos Aires, Argentina., Poulsen LØ; Department of Oncology, Danish Colorectal Cancer Center South, University Hospital of Southern Denmark, Vejle, Denmark.; Department of Regional Health Research, University of Southern Denmark, Odense, Denmark., Lindebjerg J; Department of Oncology, Danish Colorectal Cancer Center South, University Hospital of Southern Denmark, Vejle, Denmark.; Department of Regional Health Research, University of Southern Denmark, Odense, Denmark., O'Connor JM; GI Clinical Oncology and GI Surgical Oncology, Instituto Alexander Fleming, Buenos Aires, Argentina., Scripcariu V; 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi, Romania.; Surgical Oncology Unit, Regional Institute of Oncology, Iasi, Romania., Dimofte MG; Department of Surgical Oncology, Regional Institute of Oncology (IRO), Iasi, Romania.; 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi, Romania., Gérard JP; Department of Radiotherapy, Centre Antoine-Lacassagne, Nice, France., Chalabi M; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Figueiredo N; Colorectal Surgery, Digestive Department, Champalimaud Foundation, Lisbon, Portugal., Perez RO; Division of Colorectal Surgery, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil.; Department of Surgical Oncology, Beneficencia Portuguesa Hospital, São Paulo, Brazil.; Angelita and Joaquim Gama Institute, São Paulo, Brazil., Habr-Gama A; Division of Colorectal Surgery, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil.; Department of Surgical Oncology, Beneficencia Portuguesa Hospital, São Paulo, Brazil.; Angelita and Joaquim Gama Institute, São Paulo, Brazil., Galon J; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Cordeliers Research Center, Sorbonne University, University Paris Cité, Paris, France., Hansen TF; Department of Oncology, Danish Colorectal Cancer Center South, University Hospital of Southern Denmark, Vejle, Denmark.; Department of Regional Health Research, University of Southern Denmark, Odense, Denmark., Jensen LH; Department of Oncology, Danish Colorectal Cancer Center South, University Hospital of Southern Denmark, Vejle, Denmark.; Department of Regional Health Research, University of Southern Denmark, Odense, Denmark., Beets G; Department of Surgery, Netherlands Cancer Institute, Antoni van Leeuwenhoek, Amsterdam, the Netherlands.; GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands., Zeitoun G; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Cordeliers Research Center, Sorbonne University, University Paris Cité, Paris, France.; Immunomonitoring Platform, Laboratory of Immunology, Assistance Publique-Hôpitaux de Paris (AP-HP), Georges Pompidou European Hospital, Paris, France., Pagès F; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.; Equipe Labellisée Ligue Contre le Cancer, Paris, France.; Cordeliers Research Center, Sorbonne University, University Paris Cité, Paris, France.; Immunomonitoring Platform, Laboratory of Immunology, Assistance Publique-Hôpitaux de Paris (AP-HP), Georges Pompidou European Hospital, Paris, France.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Jan 01; Vol. 42 (1), pp. 70-80. Date of Electronic Publication: 2023 Oct 03.

Long-term Quality of Life and Functional Outcome of Patients With Rectal Cancer Following a Watch-and-Wait Approach.

Autor: Custers PA; Department of Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands.; GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands., van der Sande ME; Department of Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands.; GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands., Grotenhuis BA; Department of Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands., Peters FP; Department of Radiation Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands.; Department of Radiation Oncology, Leiden University Medical Centre, Leiden, the Netherlands., van Kuijk SMJ; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, Maastricht, the Netherlands., Beets GL; Department of Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands.; GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands., Breukink SO; GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands.; Department of Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands.; NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands.

Publikováno v: JAMA surgery [JAMA Surg] 2023 May 01; Vol. 158 (5), pp. e230146. Date of Electronic Publication: 2023 May 10.

Features on Endoscopy and MRI after Treatment with Contact X-ray Brachytherapy for Rectal Cancer: Explorative Results.

Autor: Custers PA; Department of Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands.; Department of Radiation Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands.; GROW School for Oncology and Developmental Biology, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands., Maas M; Department of Radiology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands., Lambregts DMJ; Department of Radiology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands., Beets-Tan RGH; GROW School for Oncology and Developmental Biology, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands.; Department of Radiology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands., Beets GL; Department of Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands.; GROW School for Oncology and Developmental Biology, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands., Peters FP; Department of Radiation Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands.; Department of Radiation Oncology, Leiden University Medical Centre, P.O. Box 9600, 2300 RC Leiden, The Netherlands., Marijnen CAM; Department of Radiation Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands.; Department of Radiation Oncology, Leiden University Medical Centre, P.O. Box 9600, 2300 RC Leiden, The Netherlands., van Leerdam ME; Department of Gastroenterology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands.; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, P.O. Box 9600, 2300 RC Leiden, The Netherlands., Huibregtse IL; Department of Gastroenterology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands., van Triest B; Department of Radiation Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, P.O. Box 90203, 1006 BE Amsterdam, The Netherlands.

Publikováno v: Cancers [Cancers (Basel)] 2022 Nov 13; Vol. 14 (22). Date of Electronic Publication: 2022 Nov 13.

Selected stage IV rectal cancer patients managed by the watch-and-wait approach after pelvic radiotherapy: a good alternative to total mesorectal excision surgery?

Autor: Custers PA; Department of Surgery, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands.; GROW School for Oncology and Developmental Biology - Maastricht University, Maastricht, The Netherlands., Hupkens BJP; Department of Radiotherapy, Maastricht University Medical Centre (MAASTRO), Maastricht, The Netherlands., Grotenhuis BA; Department of Surgery, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands., Kuhlmann KFD; Department of Surgery, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands., Breukink SO; Department of Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands., Beets GL; Department of Surgery, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands.; GROW School for Oncology and Developmental Biology - Maastricht University, Maastricht, The Netherlands., Melenhorst J; Department of Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.

Publikováno v: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland [Colorectal Dis] 2022 Apr; Vol. 24 (4), pp. 401-410. Date of Electronic Publication: 2022 Jan 21.