Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma - A pilot study 164/rccm.200206-5250C

Autor: Kips, JC, O'Connor, BJ, Langley, SJ, Woodcock, A, Kerstjens, HAM, Postma, DS, Danzig, M, Cuss, F, Pauwels, RA

Publikováno v: American Journal of Respiratory and Critical Care Medicine, 167(12), 1655-1659. AMER THORACIC SOC

Antagonizing the effect of interleukin (IL)-5 is a potential new treatment strategy in allergic disorders. We evaluated the safety, biological activity, and pharmacokinetics of SCH55700, a humanized anti-human IL-5 antibody, in subjects with severe p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::43a2e0c4a5fee2fc9d86dc1402657647
https://research.rug.nl/en/publications/19645c82-3d5e-458d-b2eb-2dda1fbcf428

Inhibition of interleukin-5 with a monoclonal antibody attenuates allergic inflammation.

Autor: Danzig, M., Cuss, F.

Publikováno v: Allergy; Aug97, Vol. 52 Issue 8, p787-794, 8p

Organizational effectiveness: a key to R&D productivity.

Autor: Tollman P; The Boston Consulting Group, Inc., Exchange Place, 31st Floor, Boston, Massachusetts 02109, USA., Panier V; The Boston Consulting Group, Inc., Exchange Place, 31st Floor, Boston, Massachusetts 02109, USA., Dosik D; The Boston Consulting Group, Inc., Exchange Place, 31st Floor, Boston, Massachusetts 02109, USA., Biondi P; Bristol-Myers Squibb Company, 345 Park Avenue, New York, New York 10154, USA., Cuss F; Bristol-Myers Squibb Company, 345 Park Avenue, New York, New York 10154, USA.

Publikováno v: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2016 Jul; Vol. 15 (7), pp. 441-2. Date of Electronic Publication: 2016 Jun 17.

Th2 cytokines and asthma. The role of interleukin-5 in allergic eosinophilic disease.

Autor: Greenfeder, S, Umland, S P, Cuss, F M, Chapman, R W, Egan, R W

Publikováno v: Respiratory Research; 2001, Vol. 2, p71-79, 9p

Francis Cuss.

Autor: Cuss F, Mullard A

Publikováno v: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2015 Oct; Vol. 14 (10), pp. 672-3. Date of Electronic Publication: 2015 Sep 11.