Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Cushla McKinney"'
Autor:
Tahzeeb Fatima, Cushla McKinney, Tanya J. Major, Lisa K. Stamp, Nicola Dalbeth, Cory Iverson, Tony R. Merriman, Jeffrey N. Miner
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Abstract Background Ferritin positively associates with serum urate and an interventional study suggests that iron has a role in triggering gout flares. The objective of this study was to further explore the relationship between iron/ferritin and ura
Externí odkaz:
https://doaj.org/article/de1e9a5be8cd4b8193548914acc94f83
Autor:
Humaira Rasheed, Cushla McKinney, Lisa K Stamp, Nicola Dalbeth, Ruth K Topless, Richard Day, Diluk Kannangara, Kenneth Williams, Malcolm Smith, Matthijs Janssen, Tim L Jansen, Leo A Joosten, Timothy R Radstake, Philip L Riches, Anne-Kathrin Tausche, Frederic Lioté, Leo Lu, Eli A Stahl, Hyon K Choi, Alexander So, Tony R Merriman
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147939 (2016)
Deposition of crystallized monosodium urate (MSU) in joints as a result of hyperuricemia is a central risk factor for gout. However other factors must exist that control the progression from hyperuricaemia to gout. A previous genetic association stud
Externí odkaz:
https://doaj.org/article/6f7b6963d1324f409c1f107c1db7ad96
Autor:
Suneeth F Mathew, Caillan Crowe-McAuliffe, Ryan Graves, Tony S Cardno, Cushla McKinney, Elizabeth S Poole, Warren P Tate
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122176 (2015)
HIV-1 utilises -1 programmed ribosomal frameshifting to translate structural and enzymatic domains in a defined proportion required for replication. A slippery sequence, U UUU UUA, and a stem-loop are well-defined RNA features modulating -1 frameshif
Externí odkaz:
https://doaj.org/article/87d15fa289194209897c68af85fac57f
Autor:
María Teruel, Cushla McKinney, Alejandro Balsa, Dora Pascual-Salcedo, Luis Rodriguez-Rodriguez, Ana M Ortiz, Carmen Gómez-Vaquero, Miguel A González-Gay, Malcolm Smith, Torsten Witte, Tony Merriman, Benedicte A Lie, Javier Martin
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68295 (2013)
Given the role of CD247 in the response of the T cells, its entailment in autoimmune diseases and in order to better clarify the role of this gene in RA susceptibility, we aimed to analyze CD247 gene variants previously associated with other autoimmu
Externí odkaz:
https://doaj.org/article/bea5e59dba594d1fa17ff9a0e035068d
Autor:
Ramona A, Eiholzer, Sunali, Mehta, Marina, Kazantseva, Catherine J, Drummond, Cushla, McKinney, Katie, Young, David, Slater, Brianna C, Morten, Kelly A, Avery-Kiejda, Annette, Lasham, Nicholas, Fleming, Helen R, Morrin, Karen, Reader, Janice A, Royds, Michael, Landmann, Simone, Petrich, Roger, Reddel, Lily, Huschtscha, Ahmad, Taha, Noelyn A, Hung, Tania L, Slatter, Antony W, Braithwaite
Publikováno v:
Cancers
Simple Summary We investigated the influence of genetic variants, called single nucleotide polymorphisms (SNP) in the TP53 tumour suppressor gene, on cancer risk, clinical features and TP53 isoform levels. These SNPs were significantly over-represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d8e0160bb47b142578a878619fb7341
https://pubmed.ncbi.nlm.nih.gov/32882831
https://pubmed.ncbi.nlm.nih.gov/32882831
Autor:
Torsten Kleffmann, Puja Bhatia, Cushla McKinney, Tara K. Bartolec, Maree Gould, Anthony J. Cesare, Heather E. Cunliffe, Chandra S. Verma, Kim Parker, Sunali Mehta, Antony W. Braithwaite, Rhodri Harfoot, Michael Algie, Scott B. Cohen, Alistair J. Fisher, Srinivasaraghavan Kannan, Adele G. Woolley
Publikováno v:
Cancers
Volume 12
Issue 2
Cancers, Vol 12, Iss 2, p 315 (2020)
Volume 12
Issue 2
Cancers, Vol 12, Iss 2, p 315 (2020)
Elevated levels of nuclear Y-box binding protein 1 (YB-1) are linked to poor prognosis in cancer. It has been proposed that entry into the nucleus requires specific proteasomal cleavage. However, evidence for cleavage is contradictory and high YB-1 l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9085262029790105cb2e73b98fe98c16
Autor:
Megan Chircop, Tara K. Bartolec, Weini Ma, Antony W. Braithwaite, Rhodri Harfoot, Srinivasaraghavan Kannan, Tariq Al-Jabry, Maree Gould, Anthony J. Cesare, Scott B. Cohen, Jessie Zhang, V. Pragathi Masamsetti, Puja Bhatia, Cushla McKinney, Chandra S. Verma, Adele G. Woolley, Sunali Mehta, Luke Henderson, Kim Parker, Torsten Kleffmann, Michael Algie
Publikováno v:
Cancers
Volume 12
Issue 9
Cancers, Vol 12, Iss 2473, p 2473 (2020)
Volume 12
Issue 9
Cancers, Vol 12, Iss 2473, p 2473 (2020)
High levels of the cold shock protein Y-box-binding protein-1, YB-1, are tightly correlated with increased cell proliferation and progression. However, the precise mechanism by which YB-1 regulates proliferation is unknown. Here, we found that YB-1 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304e92f8ffe99c7357c00eb1efd76b7b
https://hdl.handle.net/10356/146593
https://hdl.handle.net/10356/146593
Autor:
Sunali, Mehta, Cushla, McKinney, Michael, Algie, Chandra S, Verma, Srinivasaraghavan, Kannan, Rhodri, Harfoot, Tara K, Bartolec, Puja, Bhatia, Alistair J, Fisher, Maree L, Gould, Kim, Parker, Anthony J, Cesare, Heather E, Cunliffe, Scott B, Cohen, Torsten, Kleffmann, Antony W, Braithwaite, Adele G, Woolley
Publikováno v:
Cancers
Elevated levels of nuclear Y-box binding protein 1 (YB-1) are linked to poor prognosis in cancer. It has been proposed that entry into the nucleus requires specific proteasomal cleavage. However, evidence for cleavage is contradictory and high YB-1 l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e73650dfda3f5e36e3c3bb51d441bc8d
https://pubmed.ncbi.nlm.nih.gov/32013098
https://pubmed.ncbi.nlm.nih.gov/32013098
Autor:
Janice A. Royds, Sunali Mehta, Simone Petrich, Brianna C. Morten, Kelly A. Avery-Kiejda, Helen Morrin, Lily I. Huschtscha, Michael Landmann, Annette Lasham, David Slater, Cushla McKinney, Marina Kazantseva, Ahmad Taha, Noelyn Hung, Karen L Reader, Nicholas I. Fleming, Ramona A Eiholzer, Katie Young, Roger R. Reddel, Antony W. Braithwaite, Catherine J. Drummond, Tania L. Slatter
Publikováno v:
Cancers
Volume 12
Issue 9
Cancers, Vol 12, Iss 2472, p 2472 (2020)
Volume 12
Issue 9
Cancers, Vol 12, Iss 2472, p 2472 (2020)
We investigated the influence of selected TP53 SNPs in exon 4 and intron 4 on cancer risk, clinicopathological features and expression of TP53 isoforms. The intron 4 SNPs were significantly over-represented in cohorts of mixed cancers compared to thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25103f719df0042d8546bd2e84d5a2d
https://doi.org/10.3390/cancers12092472
https://doi.org/10.3390/cancers12092472
Autor:
Lisa K. Stamp, Cushla McKinney, Cory Iverson, Jeffrey N. Miner, Tony R. Merriman, Nicola Dalbeth, Tanya J Major, Tahzeeb Fatima
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Background Ferritin positively associates with serum urate and an interventional study suggests that iron has a role in triggering gout flares. The objective of this study was to further explore the relationship between iron/ferritin and urate/gout.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807a92f72dae691ff61cbf69f8cfdd1a
https://doi.org/10.1186/s13075-018-1668-y
https://doi.org/10.1186/s13075-018-1668-y